• Article  

      Cationic nanoparticles have superior transvascular flux into solid tumors: Insights from a mathematical model 

      Stylianopoulos, T.; Soteriou, K.; Fukumura, D.; Jain, R. K. (2013)
      Despite their great promise, only a few nanoparticle formulations have been approved for clinical use in oncology. The failure of nano-scale drugs to enhance cancer therapy is in large part due to inefficient delivery. To ...
    • Conference Object  

      CORONA: A coordinate and routing system for nanonetworks 

      Tsioliaridou, A.; Liaskos, Christos K.; Ioannidis, S.; Pitsillides, Andreas (Association for Computing Machinery, Inc, 2015)
      The present paper introduces a joint coordinate and routing system (CORONA) which can be deployed dynamically on a 2D ad-hoc nanonetwork. User-selected nodes are used as anchor-points at the setup phase. All nodes then ...
    • Article  

      Delivery of molecular and nanoscale medicine to tumors: Transport barriers and strategies 

      Chauhan, V. P.; Stylianopoulos, T.; Boucher, Y.; Jain, R. K. (2011)
      Tumors are similar to organs, with unique physiology giving rise to an unusual set of transport barriers to drug delivery. Cancer therapy is limited by nonuniform drug delivery via blood vessels, inhomogeneous drug transport ...
    • Article  

      Deposition and nanotribological characterization of Sub-100-nm thick protective Ti-based coatings for miniature applications 

      Polychronopoulou, K.; Lee, J.; Tsotsos, C.; Demas, N. G.; Meschewski, R. L.; Rebholz, Claus; Polycarpou, A. A. (2011)
      Ti-based protective thin films with thicknesses below 100 nm, intended for miniature applications were deposited using physical vapor deposition magnetron sputtering. X-ray diffraction (XRD), scanning electron microscopy, ...
    • Conference Object  

      Design rules for cancer nanomedicines 

      Stylianopoulos, T.; Soteriou, K.; Fukumura, D.; Jain, R. K. (Affiliation: Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, CyprusAffiliation: Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United StatesCorrespondence Address: Stylianopoulos, T.Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus, 2012)
      The use of nanotechnology has offered new hope for cancer detection, prevention and treatment. Nanoparticle formulations are advantageous over conventional chemotherapy because they can incorporate multiple diagnostic and ...
    • Article  

      Lightweight, self-tuning data dissemination for dense nanonetworks 

      Tsioliaridou, A.; Liaskos, Christos K.; Ioannidis, S.; Pitsillides, Andreas (2015)
      A nanonetwork comprises a high number of autonomous nodes with wireless connectivity, assembled at micro-to-nanoscale. In general, manufacturing and cost considerations imply that nanonetworking approaches should have ...
    • Article  

      Nanostructure and doping stimulated phase separation in high-ZT Mg2Si0.55Sn0.4Ge0.05 compounds 

      Polymeris, G. S.; Vlachos, N.; Khan, A. U.; Hatzikraniotis, E.; Lioutas, C. B.; Delimitis, A.; Pavlidou, E.; Paraskevopoulos, K. M.; Kyratsi, Theodora (2015)
      A study was attempted on the structural properties across all relevant length-scales for Mg2(Si,Sn,Ge)-type solid solutions of the formula Mg2Si0.55- ySn0.40Ge0.05(Bi,Sb)y. The study focuses on three families of samples, ...