Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Title
Now showing items 548-567 of 677
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Article
Samba, a Xenopus hnRNP expressed in neural and neural crest tissues
(2009)RNA binding proteins regulate gene expression at the posttranscriptional level and play important roles in embryonic development. Here, we report the cloning and expression of Samba, a Xenopus hnRNP that is maternally ...
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Article
Screening for Familial Mediterranean Fever M694V and V726A mutations in the Greek population.
(2009)Familial Mediterranean Fever (FMF) is an autosomal recessive genetic disease that primarily affects populations surrounding the Mediterranean basin. FMF patients suffer from recurrent episodes of fever accompanied by ...
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Article
Screening for mutations in kidney-related genes using SURVEYOR nuclease for cleavage at heteroduplex mismatches
(2009)SURVEYOR is a new mismatch-specific plant DNA endonuclease that is very efficient for mutation scanning in heteroduplex DNA. It is much faster, cheaper, more sensitive, and easier to perform than other "traditional" mutation ...
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Article
Screening of the PKD1 duplicated region reveals multiple single nucleotide polymorphisms and a de novo mutation in Hellenic polycystic kidney disease families.
(2000)Mutations in the PKD1 gene account for approximately 85% of cases with autosomal dominant polycystic kidney disease (ADPKD1
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Article
Selection of cancer chemopreventive agents based on inhibition of topoisomerase II activity
(2000)The present study was undertaken to determine if in vitro inhibition of one or both of the two most dominant mammalian DNA topoisomerases (topos) is common among chemopreventive agents. To determine if an agent was a topo ...
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Article
Selective activation of TNFR1 and NF-ΚB inhibition by a novel biyouyanagin analogue promotes apoptosis in acute leukemia cells
(2016)Background: Acquired resistance towards apoptosis is a hallmark of cancer. Elimination of cells bearing activated oncogenes or stimulation of tumor suppressor mediators may provide a selection pressure to overcome resistance. ...
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Article
Separation of the complexes formed between the regulatory and catalytic subunits of cyclic adenosine monophosphate-dependent protein kinase and topoisomerase I activity in preovulatory follicle-enriched immature rat ovaries
(1989)Our previous studies have shown that the regulatory subunits of the type II form of cAMP-dependent protein kinase (R‖) present in soluble extracts of immature rat ovaries elute from diethylaminoethyl-cellulose as three ...
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Article
Sequence evidence for common ancestry of eukaryotic endomembrane coatomers
(2016)Eukaryotic cells are defined by compartments through which the trafficking of macromolecules is mediated by large complexes, such as the nuclear pore, transport vesicles and intraflagellar transport. The assembly and ...
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Article
A sequence polymorphism in the 3′-nontranslated region of the proα1 chain of type I procollagen
(1990)
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Article
Serum total homocysteine, folate, 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C→T genotype and subclinical atherosclerosis
(2009)Objective : To determine the relationship of serum total homocysteine (tHcy), serum folate and 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C→T genotype with ultrasonic arterial wall measurements associated with ...
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Article
A serum-free and defined medium for the culture of mammalian postimplantation embryos
(2015)Whole embryo culture (WEC) of postimplantation rodent embryos is widely used for the study of mammalian embryogenesis and developmental toxicity testing. Its major advantage is that it allows direct access to embryos for ...
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Article
Sex determination of scopoli's shearwater (calonectris diomedea) juveniles: A combined molecular and morphometric approach
(2013)The absence of juvenile sexual dimorphism in birds often impedes sex determination using external morphology. We examined sex ratio variation in Scopoli's Shearwater (Calonectris diomedea) fledglings (n = 135) on a Strofades ...
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Article
Shared mechanisms in stemness and carcinogenesis: Lessons from oncogenic viruses
(2013)A rise in technologies for epigenetic reprogramming of cells to pluripotency, highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared ...
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Article
Short communication: Molecular epidemiology of HIV type 1 infection in northern Greece (2009-2010): Evidence of a transmission cluster of HIV Type 1 Subtype A1 drug-resistant strains among men who have sex with men
(2014)A prospective molecular epidemiology study of HIV-1 infection was conducted in newly diagnosed and antiretroviral-naive patients in Northern Greece between 2009 and 2010 using a predefined enrolling strategy. Phylogenetic ...
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Article
Signaling mechanisms controlling cell fate and embryonic patterning
(2012)During development, signaling pathways specify cell fates by activating transcriptional programs in response to extracellular signals. Extensive studies in the past 30 years have revealed that surprisingly fewpathways exist ...
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Article
Significant pairwise co-occurrence patterns are not the rule in the majority of biotic communities
(2012)Our aim was to investigate species co-occurrence patterns in a large number of published biotic communities, in order to document to what extent species associations can be found in presence-absence matrices. We also aim ...
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Article
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27
(2004)Polycomb group (PcG) complexes 2 and 3 are involved in transcriptional silencing. These complexes contain a histone lysine methyltransferase (HKMT) activity that targets different lysine residues on histones H1 or H3 in ...
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Article
A simple mechanochemical model for calcium signalling in embryonic epithelial cells
(2019)Calcium signalling is one of the most important mechanisms of information propagation in the body. In embryogenesis the interplay between calcium signalling and mechanical forces is critical to the healthy development of ...
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Article
Simple null model analysis subsumes a new species co-occurrence index: A comment on Mainali et al. (2022)
(Wiley, 2022-10-02)Recently, Mainali et al. (2022, termed MSSF henceforth) proposed a new index of pair-wise species co-occurrence based on the log odds ratio α of conditional occurrence probability. Under the assumption that the total numbers ...
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Book Chapter
Single and multiplexed fluorescent in situ hybridization using quantum dots nanocrystals in Xenopus
(Springer New York, 2015)The photostability and narrow emission spectra of quantum dots (QDs) make them ideal candidates for whole-mount fluorescent in situ hybridization. Here we describe a method for non-amplified, single and multiplexed whole-mount ...