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Mitoxantrone (novantrone*) as single agent and in combination chemotherapy in the treatment of advanced breast cancer
(1983)
Nineteen out of 62 evaluable patients with advanced breast cancer achieved an objective tumour response to mitoxantrone (31%) given in a dose of 12-14 mg/m2 by i.v. infusion repeated at 3-weekly intervals. The response ...
The clinical picture of primary Sjogren's syndrome: A retrospective study
(1982)
The clinical and laboratory features of 47 patients with primary Sjogren's syndrome, confirmed by lip biopsy, were analyzed in this study. The majority of our patients had the classical signs and symptoms of Sjogren's ...
Mitoxantrone: An active new agent in the treatment of advanced breast cancer
(1984)
Sixty-five patients with advanced breast carcinoma were treated with mitoxantrone, an anthracenedione with structural similarities to adriamycin. The series included 26 patients who had received no prior chemotherapy. ...
Immunization of patients with sjögren's syndrome with pneumococcal polysaccharide vaccine
(1980)
Thirty‐two patients with Sjögren's syndrome were randomly selected to receive either multivalent pneumococcal polysaccharide vaccine or saline placebo in a double‐blind study. Among placebo treated patients, levels of ...
Correlative histologic and serologic findings of sicca syndrome in patients with systemic lupus erythematosus
(1980)
We prospectively evaluated 24 patients with systemic lupus erythematosus for clinical, histologic, and serologic evidence of sicca syndrome. Abnormalities suggestive of sicca syndrome in patients with systemic lupus were ...
Is androgen substitution necessary in hypogonadal patients when they are treated with chemotherapy for malignant diseases?
(1989)
A patient with hypogonadotropic hypogonadism owing to endogenous gonadotropin releasing hormone deficiency, who developed Hodgkin's disease is described. Chemotherapy administration caused prolonged and life‐threatening ...