Browsing by Author "Antoniades, Athos"

Now showing items 1-16 of 16

    • Article  

      Abductive logic programming in the clinical management of HIV/AIDS 

      Ray, O.; Antoniades, Athos; Kakas, Antonis C.; Demetriades, Ioannis (2006)
      This paper presents a new Abductive Logic Programming (ALP) approach for assisting clinicians in the selection of antiretroviral drugs for patients infected with Human Immunodeficiency Virus (HIV). The approach is comparable ...
    • Conference Object  

      A binary format for genetic data designed for large whole genome studies that enable both marker and strand based analyses 

      Antoniades, Athos; Loizou, L.; Aristodimou, Aristos; Pattichis, Constantinos S. (2008)
      Recent advances in genotyping technology have enabled large studies with data from thousands of subjects to contain half a million or more of single nucleotide polymorphisms (SNPs) marker per subject. This rapid increase ...
    • Conference Object  

      Clustering subjects in genetic studies with self organizing maps 

      Aristodimou, Aristos; Antoniades, Athos; Pattichis, Constantinos S. (2012)
      Several machine learning techniques have been applied for finding multi-loci associations among Single Nucleotide Polymorphisms (SNPs) and a disease. In this paper it is investigated whether Self Organizing Maps (SOMs) can ...
    • Conference Object  

      A computationally fast measure of epistasis for 2 SNPs and a categorical phenotype 

      Antoniades, Athos; Matthews, P. M.; Pattichis, Constantinos S.; Galwey, N. W. (2010)
      Complex diseases may be caused by interactions or combined effects between multiple genetic and environmental factors. One of the main limitations of testing for interaction between genetic loci in large whole genome studies ...
    • Article  

      A computationally fast measure of epistasis for 2 SNPs and a categorical phenotype. 

      Antoniades, Athos; Matthews, P. M.; Pattichis, Constantinos S.; Galwey, N. W. (2010)
      Complex diseases may be caused by interactions or combined effects between multiple genetic and environmental factors. One of the main limitations of testing for interaction between genetic loci in large whole genome studies ...
    • Doctoral Thesis  Open Access

      Discovering disease associated gene-gene interactions: A two SNP interaction analysis framework 

      Antoniades, Athos (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2011-05)
      Στις πλείστες κληρονομικές ασθένειες η προδιάθεση ατόμον επηρεάζεται από αλληλεπιδράσεις μεταξύ πολλαπλών γενετικών περιοχών και περιβαλλοντικών παραγόντων. Οι παραδοσιακές μέθοδοι γενετικής ανάλυσης έχουν συγκεντρωθεί στη ...
    • Conference Object  

      Discovering genetic polymorphism associated with gene expression levels across the whole genome 

      Antoniades, Athos; Kalvari, Ioanna; Pattichis, Constantinos S.; Jones, N.; Matthews, P. M.; Domenici, E.; Muglia, P. (2009)
      Genetic differences have been shown to contribute to gene expression variability. A complete evaluation of the associations between a whole genome scan with 550k Single Nucleotide Polymorphisms (SNPs) and 54k detectable ...
    • Conference Object  

      The effects of applying cell-suppression and perturbation to aggregated genetic data 

      Antoniades, Athos; Keane, J.; Aristodimou, Aristos; Philipou, Christa; Constantinou, Andreas I.; Georgousopoulos, Christos; Tozzi, Federica; Kyriacou, Kyriacos C.; Hadjisavvas, Andreas; Loizidou, Maria A.; Demetriou, Christiana A.; Pattichis, Constantinos S. (2012)
      The key test for confidence in any association discovered within the medical domain is replication testing. That is, the ability of the association to be detected in independent populations. At the same time, in order to ...
    • Article  

      Introductory editorial to the special issue on systems medicine for the delivery of better healthcare services 

      Antoniades, Athos; Pattichis, Constantinos S.; Schizas, Christos N.; Bamidis, Panagiotis D. (2017)
    • Conference Object  

      Linked2Safety: A secure linked data medical information space for semantically-interconnecting EHRs advancing patients' safety in medical research 

      Antoniades, Athos; Georgousopoulos, Christos; Forgo, N.; Aristodimou, Aristos; Tozzi, Federica; Hasapis, Panagiotis; Perakis, Konstantinos; Bouras, Thanassis D.; Alexandrou, Dimitrios Al; Kamateri, E.; Panopoulou, E.; Tarabanis, K.; Pattichis, Constantinos S. (2012)
      Electronic Health Records (EHRs) contain an increasing wealth of medical information. They have the potential to help significantly in advancing medical research, as well as improve health policies, providing society with ...
    • Article  

      Medical content searching, retrieving, and sharing over the internet: Lessons learned from the meducator through a scenario-based evaluation 

      Antoniades, Athos; Nicolaidou, I.; Spachos, D.; Mylläri, J.; Giordano, D.; Dafli, E.; Mitsopoulou, E.; Schizas, Christos N.; Pattichis, Constantinos S.; Nikolaidou, M.; Bamidis, Panagiotis D. (2015)
      Background: The mEducator Best Practice Network (BPN) implemented and extended standards and reference models in e-learning to develop innovative frameworks as well as solutions that enable specialized state-of-the-art ...
    • Conference Object  

      Molecular clustering via knowledge mining from biomedical scientific corpora 

      Hasapis, Panagiotis; Ntalaperas, Dimitrios; Kannas, Christos C.; Aristodimou, Aristos; Alexandrou, Dimitrios Al; Bouras, Thanassis D.; Georgousopoulos, Christos; Antoniades, Athos; Pattichis, Constantinos S.; Constantinou, Andreas I. (2013)
      In this paper, an architecture is presented that allows the extraction of argumentation clauses that might exist in publications, in order to perform molecular clustering on referenced molecules. Grammar rules are defined ...
    • Conference Object  

      Molecular clustering via knowledge mining from biomedical scientific corporaAAA 

      Hasapis, Panagiotis; Ntalaperas, Dimitrios; Kannas, Christos C.; Aristodimou, Aristos; Alexandrou, Dimitrios Al; Bouras, Thanassis D.; Georgousopoulos, Christos; Antoniades, Athos; Pattichis, Constantinos S.; Constantinou, Andreas I. (2013)
      In this paper, an architecture is presented that allows the extraction of argumentation clauses that might exist in publications, in order to perform molecular clustering on referenced molecules. Grammar rules are defined ...
    • Article  

      Nature and consequences of biological reductionism for the immunological study of infectious diseases 

      Rivas, A. L.; Leitner, G.; Jankowski, M. D.; Hoogesteijn, A. L.; Iandiorio, M. J.; Chatzipanagiotou, S.; Ioannidis, A.; Blum, S. E.; Piccinini, R.; Antoniades, Athos; Fazio, J. C.; Apidianakis, Yiorgos; Fair, J. M.; Van Regenmortel, M. H. V. (2017)
      Evolution has conserved "economic" systems that perform many functions, faster or better, with less. For example, three to five leukocyte types protect from thousands of pathogens. To achieve so much with so little, ...
    • Article  

      Type 2 diabetes susceptibility in the Greek-Cypriot population: Replication of associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 polymorphisms 

      Votsi, C.; Toufexis, C.; Michailidou, K.; Antoniades, Athos; Skordis, Nicos A.; Karaolis, Minas A.; Pattichis, Constantinos S.; Christodoulou, Kyproula (2017)
      Type 2 diabetes (T2D) has been the subject of numerous genetic studies in recent years which revealed associations of the disease with a large number of susceptibility loci. We hereby initiate the evaluation of T2D ...
    • Article  

      A virtual emergency telemedicine serious game in medical training: A quantitative, professional feedback-informed evaluation study 

      Nicolaidou, I.; Antoniades, Athos; Constantinou, Renos; Marangos, C.; Kyriacou, Efthyvoulos C.; Bamidis, Panagiotis D.; Dafli, E.; Pattichis, Constantinos S. (2015)
      Background: Serious games involving virtual patients in medical education can provide a controlled setting within which players can learn in an engaging way, while avoiding the risks associated with real patients. Moreover, ...