• Article  

      Big events in Greece and HIV infection among people who inject drugs 

      Nikolopoulos, Georgios K.; Sypsa, V.; Bonovas, Stefanos; Paraskeva, D.; Malliori-Minerva, Melpomeni; Hatzakis, A.; Friedman, Samuel R. (2015)
      Big Events are processes like macroeconomic transitions that have lowered social well-being in various settings in the past. Greece has been hit by the global crisis and experienced an HIV outbreak among people who inject ...
    • Article  

      Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme 

      Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)
      Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...
    • Article  

      Developing Measures of Pathways that May Link Macro Social/Structural Changes with HIV Epidemiology 

      Pouget, E. R.; Sandoval, M.; Nikolopoulos, Georgios K.; Mateu-Gelabert, Pedro; Rossi, D.; Smyrnov, P.; Jones, Yolanda; Friedman, Samuel R. (2016)
      Macro-social/structural events (“big events”) such as wars, disasters, and large-scale changes in policies can affect HIV transmission by making risk behaviors more or less likely or by changing risk contexts. The purpose ...
    • Article  

      Economic recession and emergence of an HIV-1 outbreak among drug injectors in Athens metropolitan area: A longitudinal study 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Fotiou, Anastasios; Tsiara, Chrissa G.; Paraskeva, D.; Sypsa, V.; Lazanas, Marios; Gargalianos, Panagiotis; Psichogiou, M.; Skoutelis, A.; Wiessing, L.; Friedman, Samuel R.; Jarlais, Don C. Des; Terzidou, M.; Kremastinou, Jenny; Malliori-Minerva, Melpomeni; Hatzakis, A. (2013)
      Background: During 2011, a dramatic increase (1600%) of reported HIV-1 infections among injecting drug users (IDUs) was noted in Athens, Greece. We herein assess the potential causal pathways associated with this outbreak. ...
    • Article  

      Evaluation of the limiting antigen avidity EIA (LAg) in people who inject drugs in Greece 

      Nikolopoulos, Georgios K.; Katsoulidou, Antigoni; Kantzanou, Maria; Rokka, C.; Tsiara, Chrissa G.; Sypsa, V.; Paraskeva, D.; Psichogiou, M.; Friedman, Samuel R.; Hatzakis, A. (2017)
      This analysis assessed the utility of the limiting antigen avidity assay (LAg). Samples of people who inject drugs (PWID) in Greece with documented duration of HIV-1 infection were tested by LAg. A LAg-normalized optical ...
    • Article  

      The global spread of HIV-1 subtype B epidemic 

      Magiorkinis, Gkikas; Angelis, K.; Mamais, I.; Katzourakis, A.; Hatzakis, A.; Albert, J.; Lawyer, G.; Hamouda, O.; Struck, D.; Vercauteren, J.; Wensing, A.; Alexiev, I.; Åsjö, B.; Balotta, C.; Gomez, P.; Camacho, R. J.; Coughlan, S.; Griskevicius, A.; Grossman, Z.; Horban, A.; Kostrikis, L. G.; Lepej, S. J.; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paredes, R.; Pollack, S. M.; Puchhammer-Stöckl, E.; Schmit, J. C.; Sonnerborg, A.; Staneková, D.; Stanojevic, M.; Stylianou, D. C.; Boucher, C. A. B.; Nikolopoulos, Georgios K.; Vasylyeva, T. I.; Friedman, Samuel R.; Vijver, D. van de; Angarano, G.; Chaix, M. L.; Luca, A. de; Korn, K.; Loveday, C.; Soriano, V.; Yerly, S.; Zazzi, M.; Vandamme, A. M.; Paraskeva, D. (2016)
      Human immunodeficiency virus type 1 (HIV-1) was discovered in the early 1980s when the virus had already established a pandemic. For at least three decades the epidemic in the Western World has been dominated by subtype B ...
    • Article  

      Homelessness and other risk factors for HIV infection in the current outbreak among injection drug users in Athens, Greece 

      Sypsa, V.; Paraskeva, D.; Malliori-Minerva, Melpomeni; Nikolopoulos, Georgios K.; Panopoulos, A.; Kantzanou, Maria; Katsoulidou, Antigoni; Psichogiou, M.; Fotiou, Anastasios; Pharris, Anastasia; Laar, M. J. van de; Wiessing, L.; Jarlais, Don C. Des; Friedman, Samuel R.; Hatzakis, A. (2015)
      Objectives: We examined HIV prevalence and risk factors among injection drug users (IDUs) in Athens, Greece, during an HIV outbreak. Methods: We used respondent-driven sampling (RDS) to recruit 1404 IDUs to the Aristotle ...
    • Article  

      Identifying, linking, and treating people who inject drugs and were recently infected with HIV in the context of a network-based intervention 

      Nikolopoulos, Georgios K.; Psichogiou, Mina; Giallouros, George; Pantavou, Katerina; Pavlitina, Eirini; Papadopoulou, Martha; Williams, Leslie D.; Hadjikou, Andria; Kakalou, Eleni; Skoutelis, Athanasios; Protopapas, Konstantinos; Antoniadou, Anastasia; Boulmetis, George; Paraskevis, Dimitrios; Hatzakis, Angelos; Friedman, Samuel R. (2019)
      Identifying and linking people to care soon after HIV infection could limit viral transmission and protect their health. This work aims at describing the continuum of care among recently HIV-infected people who inject drugs ...
    • Article  

      Immediate impact of Hurricane Sandy on people who inject drugs in New York City 

      Pouget, E. R.; Sandoval, M.; Nikolopoulos, Georgios K.; Friedman, Samuel R. (2015)
      Over the eight months following Hurricane Sandy, of October 2012, we interviewed 300 people who inject drugs in New York City. During the week after the storm, 28% rescued others or volunteered with aid groups; 60% experienced ...
    • Article  

      Interpersonal Attacks on the Dignity of Members of HIV Key Populations: A Descriptive and Exploratory Study 

      Friedman, Samuel R.; Pouget, E. R.; Sandoval, M.; Rossi, D.; Mateu-Gelabert, Pedro; Nikolopoulos, Georgios K.; Schneider, J. A.; Smyrnov, P.; Stall, R. D. (2017)
      Attacks on peoples’ dignity help to produce and maintain stigmatization and interpersonal hostility. As part of an effort to develop innovative measures of possible pathways between structural interventions or socially-disruptive ...
    • Article  

      Measuring Altruistic and Solidaristic Orientations Toward Others among People Who Inject Drugs 

      Friedman, Samuel R.; Pouget, E. R.; Sandoval, M.; Jones, Yolanda; Nikolopoulos, Georgios K.; Mateu-Gelabert, Pedro (2015)
      The altruism and/or solidarity of people who inject drugs helps protect sex and drug partners from HIV. Research has been hindered by lack of measures. We developed and administered scales to assess them to 300 people who ...
    • Article  

      Molecular Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)–Infected Individuals in a Network-Based Intervention (Transmission Reduction Intervention Project): Phylogenetics Identify HIV-1–Infected Individuals With Social Links 

      Nikolopoulos, Georgios K.; Kostaki, Evangelia-Georgia; Pavlitina, Eirini; Williams, Leslie; Magiorkinis, Gkikas; Schneider, John; Skaathun, Britt; Morgan, Ethan; Psichogiou, Mina; Daikos, Georgios L.; Sypsa, Vana; Smyrnov, Pavlo; Korobchuk, Ania; Malliori, Meni; Hatzakis, Angelos; Friedman, Samuel R.; Paraskevis, Dimitrios (2018)
      We analyzed associations between HIV-1 transmission links, as estimated by phylogenetic analyses, and social networks. We found that 43.8% of people who inject
    • Article  

      Molecular investigation of HIV-1 cross-group transmissions during an outbreak among people who inject drugs (2011-2014) in Athens, Greece 

      Nikolopoulos, Georgios K.; Paraskevis, Dimitrios; Sypsa, Vana; Psichogiou, Mina; Pantavou, Katerina; Kostaki, Evangelia; Karamitros, Timokratis; Paraskeva, Dimitra; Schneider, John; Malliori, Melpomeni; Friedman, Samuel R.; Des Jarlais, Don C.; Daikos, Georgios L.; Hatzakis, Angelos (2018)
      New diagnoses of HIV-1 infection among people who inject drugs (PWID) rocketed in Athens, Greece between 2011 and 2014 (HIV-1 outbreak). Our aim was to identify, during that period, potential cross-group transmissions ...
    • Article  

      National income inequality and declining GDP growth rates are associated with increases in HIV diagnoses among people who inject drugs in Europe: A panel data analysis 

      Nikolopoulos, Georgios K.; Fotiou, Anastasios; Kanavou, Eleftheria; Richardson, C.; Detsis, Marios; Pharris, Anastasia; Suk, J. E.; Semenza, J. C.; Costa-Storti, Claudia; Paraskeva, D.; Sypsa, V.; Malliori-Minerva, Melpomeni; Friedman, Samuel R.; Hatzakis, A. (2015)
      Background: There is sparse evidence that demonstrates the association between macro-environmental processes and drug-related HIV epidemics. The present study explores the relationship between economic, socio-economic, ...
    • Article  

      Near Full-length Genomic Sequencing and Molecular Analysis of HIV-Infected Individuals in a Network-based Intervention (TRIP) in Athens, Greece: Evidence that Transmissions Occur More Frequently from those with High HIV-RNA 

      Nikolopoulos, Georgios K.; Kostaki, Evangelia-Georgia; Frampton, Daniel; Paraskevis, Dimitrios; Pantavou, Katerina; Ferns, Bridget; Raffle, Jade; Grant, Paul; Kozlakidis, Zisis; Hadjikou, Andria; Pavlitina, Eirini; Williams, Leslie D.; Hatzakis, Angelos; Friedman, Samuel R.; Nastouli, Eleni (2018)
      BACKGROUND: TRIP (Transmission Reduction Intervention Project) was a network-based, contact tracing approach to locate and link to care, mostly people who inject drugs (PWID) with recent HIV infection. OBJECTIVE: We ...
    • Article  

      Network characteristics of people who inject drugs within a new HIV epidemic following austerity in Athens, Greece 

      Tsang, M. A.; Schneider, J. A.; Sypsa, V.; Schumm, P.; Nikolopoulos, Georgios K.; Paraskeva, D.; Friedman, Samuel R.; Malliori-Minerva, Melpomeni; Hatzakis, A. (2015)
      Background: Greece experienced an unprecedented increase in HIV cases among drug injectors in 2011 after economic crisis. Network-level factors are increasingly understood to drive HIV transmission in emerging epidemics. ...
    • Article  

      A network intervention that locates and intervenes with recently HIV-infected persons: The Transmission Reduction Intervention Project (TRIP) 

      Nikolopoulos, Georgios K.; Pavlitina, E.; Muth, Stephen Q.; Schneider, J. A.; Psichogiou, M.; Williams, L. D.; Paraskeva, D.; Sypsa, V.; Magiorkinis, Gkikas; Smyrnov, P.; Korobchuk, Anya; Vasylyeva, T. I.; Skaathun, B.; Malliori-Minerva, Melpomeni; Kafetzopoulos, Evangelos; Hatzakis, A.; Friedman, Samuel R. (2016)
      Early treatment, soon after infection, reduces HIV transmissions and benefits patients. The Transmission Reduction Intervention Project (TRIP) evaluated a network intervention to detect individuals recently infected (in ...
    • Article  

      A Network Intervention to Locate Newly HIV Infected Persons Within MSM Networks in Chicago 

      Morgan, Ethan; Skaathun, Britt; Nikolopoulos, Georgios K.; Paraskevis, Dimitrios; Williams, Leslie D.; Smyrnov, Pavlo; Friedman, Samuel R.; Schneider, John A. (2019)
      Individuals with recent/acute HIV-infection have an increased likelihood of disease transmission. To evaluate effectiveness of identifying recent infections, we compared networks of recently and long-term HIV-infected ...
    • Article  

      Network Research Experiences in New York and Eastern Europe: Lessons for the Southern US in Understanding HIV Transmission Dynamics 

      Nikolopoulos, Georgios; Friedman, Samuel R.; Williams, Leslie; Young, April M.; Teubl, Jennifer; Paraskevis, Dimitrios; Kostaki, Evangelia; Latkin, Carl; German, Danielle; Mateu-Gelabert, Pedro; Guarino, Honoria; Vasylyeva, Tetyana I.; Skaathun, Britt; Schneider, John; Korobchuk, Ania; Smyrnov, Pavlo (2018)
      This paper presents an overview of different kinds of risk and social network methods and the kinds of research questions each can address.
    • Article  

      People with high HIV viral load within risk networks: who are these people and who refers them best? 

      Nikolopoulos, Georgios K.; Korobchuk, Anna; Davtyan, Hayk; Denisiuk, Olga; Zachariah, Rony; Paraskevis, Dimitrios; Skaathun, Britt; Schneider, John; Vasylyeva, Tetyana I.; Williams, Leslie D.; Smyrnov, Pavlo; Friedman, Samuel R. (2019)
      Introduction: Viral load is one of the most important determinants for HIV transmission. Identification of people with high viral load (PHVL) can be effective in limiting onward HIV transmission. In order to improve the ...