Browsing by Author "Hatzakis, A."

Now showing items 1-20 of 25

    • Article  

      Antiretrovirals for HIV exposure prophylaxis 

      Nikolopoulos, Georgios K.; Tsiodras, Sotirios; Bonovas, Stefanos; Hatzakis, A. (2012)
      Infection with Human Immunodeficiency Virus (HIV) remains a global public health problem. Although the epidemic has not been completely controlled, there was considerable progress in HIV prevention and treatment during the ...
    • Article  

      Apoptosis and hepatitis C virus infection in renal transplant recipients 

      Delladetsima, I.; Psichogiou, M.; Alexandrou, P.; Nikolopoulos, Georgios K.; Revenas, K.; Hatzakis, A.; Boletis, J. (2008)
      Hepatocellular injury in renal transplant recipients with hepatitis C virus (HCV) infection remains unclear. The suppressed immune response, in combination with increased viremia levels, provides a unique setting for the ...
    • Article  

      The application of HIV molecular epidemiology to public health 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Magiorkinis, Gkikas; Hodges-Mameletzis, I.; Hatzakis, A. (2016)
      HIV is responsible for one of the largest viral pandemics in human history. Despite a concerted global response for prevention and treatment, the virus persists. Thus, urgent public health action, utilizing novel interventions, ...
    • Article  

      Big events in Greece and HIV infection among people who inject drugs 

      Nikolopoulos, Georgios K.; Sypsa, V.; Bonovas, Stefanos; Paraskeva, D.; Malliori-Minerva, Melpomeni; Hatzakis, A.; Friedman, Samuel R. (2015)
      Big Events are processes like macroeconomic transitions that have lowered social well-being in various settings in the past. Greece has been hit by the global crisis and experienced an HIV outbreak among people who inject ...
    • Article  

      Condom effectiveness in reducing heterosexual HIV transmission: a systematic review and meta-analysis of studies on HIV serodiscordant couples 

      Giannou, Foteini K.; Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Talias, M.; Benetou, Vasiliki; Kantzanou, Maria; Bonovas, Stefanos; Hatzakis, A. (2016)
      Objective: This systematic review and meta-analysis aimed to reassess the effectiveness of condoms in reducing heterosexual transmission of HIV. Methods: Medline, Scopus, and the ISI Web of Science databases were searched ...
    • Article  

      Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme 

      Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)
      Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...
    • Article  

      Economic recession and emergence of an HIV-1 outbreak among drug injectors in Athens metropolitan area: A longitudinal study 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Fotiou, Anastasios; Tsiara, Chrissa G.; Paraskeva, D.; Sypsa, V.; Lazanas, Marios; Gargalianos, Panagiotis; Psichogiou, M.; Skoutelis, A.; Wiessing, L.; Friedman, Samuel R.; Jarlais, Don C. Des; Terzidou, M.; Kremastinou, Jenny; Malliori-Minerva, Melpomeni; Hatzakis, A. (2013)
      Background: During 2011, a dramatic increase (1600%) of reported HIV-1 infections among injecting drug users (IDUs) was noted in Athens, Greece. We herein assess the potential causal pathways associated with this outbreak. ...
    • Article  

      Effect of hepatitis C virus on immunological and virological responses in HIV-infected patients initiating highly active antiretroviral therapy: A meta-analysis 

      Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Dimou, Niki L.; Bagos, Pantelis G.; Saroglou, G.; Velonakis, E.; Hatzakis, A. (2013)
      Co-infection of human immunodeficiency virus (HIV) with hepatitis C virus (HCV) is rather common. In the era of highly active antiretroviral therapy (HAART), viral hepatitis could result in adverse outcomes in HIV+ patients. ...
    • Article  

      Enhanced HIV-1 surveillance using molecular epidemiology to study and monitor HIV-1 outbreaks among intravenous drug users (IDUs) in Athens and Bucharest 

      Paraskeva, D.; Paraschiv, S.; Sypsa, V.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Magiorkinis, Gkikas; Psichogiou, M.; Flampouris, Andreas; Mardarescu, Mariana; Niculescu, I.; Batan, Ionelia; Malliori-Minerva, Melpomeni; Otelea, D.; Hatzakis, A. (2015)
      Background: A significant increase in HIV-1 diagnoses was reported among Injecting Drug Users (IDUs) in the Athens (17-fold) and Bucharest (9-fold) metropolitan areas starting 2011. Methods: Molecular analyses were conducted ...
    • Article  

      Evaluation of the limiting antigen avidity EIA (LAg) in people who inject drugs in Greece 

      Nikolopoulos, Georgios K.; Katsoulidou, Antigoni; Kantzanou, Maria; Rokka, C.; Tsiara, Chrissa G.; Sypsa, V.; Paraskeva, D.; Psichogiou, M.; Friedman, Samuel R.; Hatzakis, A. (2017)
      This analysis assessed the utility of the limiting antigen avidity assay (LAg). Samples of people who inject drugs (PWID) in Greece with documented duration of HIV-1 infection were tested by LAg. A LAg-normalized optical ...
    • Article  

      The global spread of HIV-1 subtype B epidemic 

      Magiorkinis, Gkikas; Angelis, K.; Mamais, I.; Katzourakis, A.; Hatzakis, A.; Albert, J.; Lawyer, G.; Hamouda, O.; Struck, D.; Vercauteren, J.; Wensing, A.; Alexiev, I.; Åsjö, B.; Balotta, C.; Gomez, P.; Camacho, R. J.; Coughlan, S.; Griskevicius, A.; Grossman, Z.; Horban, A.; Kostrikis, L. G.; Lepej, S. J.; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paredes, R.; Pollack, S. M.; Puchhammer-Stöckl, E.; Schmit, J. C.; Sonnerborg, A.; Staneková, D.; Stanojevic, M.; Stylianou, D. C.; Boucher, C. A. B.; Nikolopoulos, Georgios K.; Vasylyeva, T. I.; Friedman, Samuel R.; Vijver, D. van de; Angarano, G.; Chaix, M. L.; Luca, A. de; Korn, K.; Loveday, C.; Soriano, V.; Yerly, S.; Zazzi, M.; Vandamme, A. M.; Paraskeva, D. (2016)
      Human immunodeficiency virus type 1 (HIV-1) was discovered in the early 1980s when the virus had already established a pandemic. For at least three decades the epidemic in the Western World has been dominated by subtype B ...
    • Article  

      HBV-DNA levels predict overall mortality in HIV/HBV coinfected individuals 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Psichogiou, M.; Hatzakis, A. (2016)
      The coinfection of Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) has been associated with increased death rates. However, the relevant research has mostly relied on serologic HBV testing [HBV surface antigen ...
    • Article  

      HIV epidemiology in Greece 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzakis, A. (2008)
      Greece has experienced early the effect of HIV/AIDS on morbidity and mortality. The era of highly active antiretroviral therapy has alleviated many of the consequences of the epidemic, however, HIV infection remains an ...
    • Article  

      HIV-1 outbreak among injecting drug users in Greece, 2011: A preliminary report 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Paraskeva, D.; Antoniadou, Anastasia; Lazanas, Marios; Gargalianos, Panagiotis; Psychogiou, M.; Malliori-Minerva, Melpomeni; Kremastinou, Jenny; Hatzakis, A. (2011)
      A significant increase (more than 10-fold) in the number of newly diagnosed HIV-1 infections among injecting drug users (IDUs) was observed in Greece during the first seven months of 2011. Molecular epidemiology results ...
    • Article  

      HIV/HBV co-infection and rate of antiretroviral treatment change after highly active antiretroviral treatment initiation in a cohort of HIV-infected patients in Greece 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2010)
      The current study investigated the impact of human immunodeficiency virus (HIV)/hepatitis B virus (HBV) co-infection on the rate of change of antiretroviral drugs after the initiation of highly active antiretroviral treatment ...
    • Article  

      Homelessness and other risk factors for HIV infection in the current outbreak among injection drug users in Athens, Greece 

      Sypsa, V.; Paraskeva, D.; Malliori-Minerva, Melpomeni; Nikolopoulos, Georgios K.; Panopoulos, A.; Kantzanou, Maria; Katsoulidou, Antigoni; Psichogiou, M.; Fotiou, Anastasios; Pharris, Anastasia; Laar, M. J. van de; Wiessing, L.; Jarlais, Don C. Des; Friedman, Samuel R.; Hatzakis, A. (2015)
      Objectives: We examined HIV prevalence and risk factors among injection drug users (IDUs) in Athens, Greece, during an HIV outbreak. Methods: We used respondent-driven sampling (RDS) to recruit 1404 IDUs to the Aristotle ...
    • Article  

      Impact of hepatitis B virus infection on the progression of AIDS and mortality in HIV-infected individuals: A cohort study and meta-analysis 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2009)
      Background. The effect of hepatitis B virus (HBV) infection on the natural history of human immunodeficiency virus (HIV) disease remains uncertain. Therefore, a retrospective cohort study was conducted to examine the ...
    • Article  

      Impact of HIV type 1 DNA levels on spontaneous disease progression: A meta-analysis 

      Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Goujard, Cecile; Katzenstein, Terese L.; Minga, Albert K.; Rouzioux, C.; Hatzakis, A. (2012)
      Several studies have reported the prognostic strength of HIV-1 DNA with variable results however. The aims of the current study were to estimate more accurately the ability of HIV-1 DNA to predict progression of HIV-1 ...
    • Article  

      Increasing prevalence of HIV-1 subtype a in Greece: Estimating epidemic history and origin 

      Paraskeva, D.; Magiorkinis, Emmanouil; Magiorkinis, Gkikas; Sypsa, V.; Paparizos, V.; Lazanas, Marios; Gargalianos, Panagiotis; Antoniadou, Anastasia; Panos, G.; Chrysos, Georgios; Sambatakou, H.; Karafoulidou, Anastasia; Skoutelis, A.; Kordossis, Theodoros; Koratzanis, Georgios; Theodoridou, M.; Daikos, Georgios L.; Nikolopoulos, Georgios K.; Pybus, O. G.; Hatzakis, A. (2007)
      Background. In North America and Europe, human immunodeficiency virus (HIV)-1 infection has typically been dominated by subtype B transmission. More recently, however, non-B subtypes have been increasingly reported in ...
    • Article  

      National income inequality and declining GDP growth rates are associated with increases in HIV diagnoses among people who inject drugs in Europe: A panel data analysis 

      Nikolopoulos, Georgios K.; Fotiou, Anastasios; Kanavou, Eleftheria; Richardson, C.; Detsis, Marios; Pharris, Anastasia; Suk, J. E.; Semenza, J. C.; Costa-Storti, Claudia; Paraskeva, D.; Sypsa, V.; Malliori-Minerva, Melpomeni; Friedman, Samuel R.; Hatzakis, A. (2015)
      Background: There is sparse evidence that demonstrates the association between macro-environmental processes and drug-related HIV epidemics. The present study explores the relationship between economic, socio-economic, ...