• Article  

      The application of HIV molecular epidemiology to public health 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Magiorkinis, Gkikas; Hodges-Mameletzis, I.; Hatzakis, A. (2016)
      HIV is responsible for one of the largest viral pandemics in human history. Despite a concerted global response for prevention and treatment, the virus persists. Thus, urgent public health action, utilizing novel interventions, ...
    • Article  

      Assessing the secular trends in the transmission of HIV in Greece 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Masgala, Aikaterini; Paraskeva, D. (2005)
      Objective: To evaluate the current trends in HIV transmission in Greece. Methods: A retrospective study of HIV infected individuals reported to the Hellenic Center for Infectious Diseases Control (HCIDC) was conducted. ...
    • Article  

      Big events in Greece and HIV infection among people who inject drugs 

      Nikolopoulos, Georgios K.; Sypsa, V.; Bonovas, Stefanos; Paraskeva, D.; Malliori-Minerva, Melpomeni; Hatzakis, A.; Friedman, Samuel R. (2015)
      Big Events are processes like macroeconomic transitions that have lowered social well-being in various settings in the past. Greece has been hit by the global crisis and experienced an HIV outbreak among people who inject ...
    • Article  

      Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme 

      Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)
      Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...
    • Article  

      Economic recession and emergence of an HIV-1 outbreak among drug injectors in Athens metropolitan area: A longitudinal study 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Fotiou, Anastasios; Tsiara, Chrissa G.; Paraskeva, D.; Sypsa, V.; Lazanas, Marios; Gargalianos, Panagiotis; Psichogiou, M.; Skoutelis, A.; Wiessing, L.; Friedman, Samuel R.; Jarlais, Don C. Des; Terzidou, M.; Kremastinou, Jenny; Malliori-Minerva, Melpomeni; Hatzakis, A. (2013)
      Background: During 2011, a dramatic increase (1600%) of reported HIV-1 infections among injecting drug users (IDUs) was noted in Athens, Greece. We herein assess the potential causal pathways associated with this outbreak. ...
    • Article  

      Enhanced HIV-1 surveillance using molecular epidemiology to study and monitor HIV-1 outbreaks among intravenous drug users (IDUs) in Athens and Bucharest 

      Paraskeva, D.; Paraschiv, S.; Sypsa, V.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Magiorkinis, Gkikas; Psichogiou, M.; Flampouris, Andreas; Mardarescu, Mariana; Niculescu, I.; Batan, Ionelia; Malliori-Minerva, Melpomeni; Otelea, D.; Hatzakis, A. (2015)
      Background: A significant increase in HIV-1 diagnoses was reported among Injecting Drug Users (IDUs) in the Athens (17-fold) and Bucharest (9-fold) metropolitan areas starting 2011. Methods: Molecular analyses were conducted ...
    • Article  

      Epidemiology of aids defining conditions in Greece 

      Masgala, Aikaterini; Nikolopoulos, Georgios K.; Tsantes, Argirio E.; Paraskeva, D. (2004)
      Objective: To examine the secular trends of all AIDS opportunistic infections to occur first (Ols) in Greece, by year, by gender and by mode of transmission. Methods: The study included all AIDS defining conditions reported ...
    • Article  

      Estimating HIV incidence and number of undiagnosed individuals living with HIV in the European union/ European economic area, 2015 

      Pharris, Anastasia; Quinten, C.; Noori, T.; Amato-Gauci, A. J.; Sighem, A. van; Schmid, D.; Rueckerl, I.; Zangerle, R.; Sasse, A.; Beckhoven, D. van; Denauw, F.; Varleva, T.; Georgieva, V.; Blazic, T. N.; Pavlic, J.; Begovac, J.; Koliou, M.; Hadjihannas, L.; Demetriou, A.; Maly, M.; Šikolová, V.; Cowan, Susan; Fouchard, J.; Rüütel, K.; Pääsukene, A. L.; Liitsola, K.; Salminen, M.; Brummer-Korvenkontio, H.; Cazein, F.; Pillonel, J.; Lot, F.; Comboroure, J.-C.; Gunsenheimer-Bartmeyer, Barbara; Heiden, M. A. Der; Kupfer, G.; Marcus, U.; Nikolopoulos, Georgios K.; Paraskeva, D.; Konte, Vasileia; Dudas, M.; Szalay, K.; Briem, H.; Sigmundsdottir, G.; Igoe, D.; O’Donnell, K.; Hurley, C.; Lyons, F.; Suligoi, B.; Caraglia, A.; Konova, S.; Erne, S.; Caplinskiene, I.; Fischer, A.; Hoffmann, P.; Melillo, J. M.; Melillo, T.; Coul, Eline Op de; David, S.; Blystad, H.; Myrberg, A. J.; Rosinska, M.; Wawer, I.; Mansinho, K.; Martins, H. C.; Melillo, T.; Mardarescu, Mariana; Truska, P.; Mikas, J.; Klavs, I.; Diaz, Alejandro; Nuñez, O.; Castillo, O.; Avdicova, Maria; Sonnerborg, A.; Kirwan, P.; Chau, C.; Okala, S.; Brown, A.; Delpech, Valerie (2016)
      Since 2011, human immunodeficiency virus (HIV) incidence appears unchanged in the European Union/ European Economic Area with between 29,000 and 33,000 new cases reported annually up to 2015. Despite evidence that HIV ...
    • Article  

      Evaluation of the limiting antigen avidity EIA (LAg) in people who inject drugs in Greece 

      Nikolopoulos, Georgios K.; Katsoulidou, Antigoni; Kantzanou, Maria; Rokka, C.; Tsiara, Chrissa G.; Sypsa, V.; Paraskeva, D.; Psichogiou, M.; Friedman, Samuel R.; Hatzakis, A. (2017)
      This analysis assessed the utility of the limiting antigen avidity assay (LAg). Samples of people who inject drugs (PWID) in Greece with documented duration of HIV-1 infection were tested by LAg. A LAg-normalized optical ...
    • Article  

      The global spread of HIV-1 subtype B epidemic 

      Magiorkinis, Gkikas; Angelis, K.; Mamais, I.; Katzourakis, A.; Hatzakis, A.; Albert, J.; Lawyer, G.; Hamouda, O.; Struck, D.; Vercauteren, J.; Wensing, A.; Alexiev, I.; Åsjö, B.; Balotta, C.; Gomez, P.; Camacho, R. J.; Coughlan, S.; Griskevicius, A.; Grossman, Z.; Horban, A.; Kostrikis, L. G.; Lepej, S. J.; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paredes, R.; Pollack, S. M.; Puchhammer-Stöckl, E.; Schmit, J. C.; Sonnerborg, A.; Staneková, D.; Stanojevic, M.; Stylianou, D. C.; Boucher, C. A. B.; Nikolopoulos, Georgios K.; Vasylyeva, T. I.; Friedman, Samuel R.; Vijver, D. van de; Angarano, G.; Chaix, M. L.; Luca, A. de; Korn, K.; Loveday, C.; Soriano, V.; Yerly, S.; Zazzi, M.; Vandamme, A. M.; Paraskeva, D. (2016)
      Human immunodeficiency virus type 1 (HIV-1) was discovered in the early 1980s when the virus had already established a pandemic. For at least three decades the epidemic in the Western World has been dominated by subtype B ...
    • Article  

      HBV-DNA levels predict overall mortality in HIV/HBV coinfected individuals 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Psichogiou, M.; Hatzakis, A. (2016)
      The coinfection of Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) has been associated with increased death rates. However, the relevant research has mostly relied on serologic HBV testing [HBV surface antigen ...
    • Article  

      HIV epidemiology in Greece 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzakis, A. (2008)
      Greece has experienced early the effect of HIV/AIDS on morbidity and mortality. The era of highly active antiretroviral therapy has alleviated many of the consequences of the epidemic, however, HIV infection remains an ...
    • Article  

      HIV-1 outbreak among injecting drug users in Greece, 2011: A preliminary report 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Paraskeva, D.; Antoniadou, Anastasia; Lazanas, Marios; Gargalianos, Panagiotis; Psychogiou, M.; Malliori-Minerva, Melpomeni; Kremastinou, Jenny; Hatzakis, A. (2011)
      A significant increase (more than 10-fold) in the number of newly diagnosed HIV-1 infections among injecting drug users (IDUs) was observed in Greece during the first seven months of 2011. Molecular epidemiology results ...
    • Article  

      HIV/HBV co-infection and rate of antiretroviral treatment change after highly active antiretroviral treatment initiation in a cohort of HIV-infected patients in Greece 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2010)
      The current study investigated the impact of human immunodeficiency virus (HIV)/hepatitis B virus (HBV) co-infection on the rate of change of antiretroviral drugs after the initiation of highly active antiretroviral treatment ...
    • Article  

      Homelessness and other risk factors for HIV infection in the current outbreak among injection drug users in Athens, Greece 

      Sypsa, V.; Paraskeva, D.; Malliori-Minerva, Melpomeni; Nikolopoulos, Georgios K.; Panopoulos, A.; Kantzanou, Maria; Katsoulidou, Antigoni; Psichogiou, M.; Fotiou, Anastasios; Pharris, Anastasia; Laar, M. J. van de; Wiessing, L.; Jarlais, Don C. Des; Friedman, Samuel R.; Hatzakis, A. (2015)
      Objectives: We examined HIV prevalence and risk factors among injection drug users (IDUs) in Athens, Greece, during an HIV outbreak. Methods: We used respondent-driven sampling (RDS) to recruit 1404 IDUs to the Aristotle ...
    • Article  

      The human immunodeficiency virus continuum of care in European Union Countries in 2013: Data and Challenges 

      Gourlay, Annabelle; Noori, T.; Pharris, Anastasia; Avdicova, Maria; Costagliola, Dominique; Cowan, Susan; Croxford, Sara; Monforte, A. D'arminio; Amo, Julia del; Delpech, Valerie; Diaz, Alejandro; Girardi, Enrico; Gunsenheimer-Bartmeyer, Barbara; Hernando, Victoria; Jose, Sophie; Leierer, Gisela; Nikolopoulos, Georgios K.; Obel, N.; Coul, E. Op De; Paraskeva, D.; Reiss, P.; Sabin, C.; Sasse, A.; Schmid, D.; Sonnerborg, A.; Spina, A.; Suligoi, B.; Supervie, V.; Touloumi, G.; Beckhoven, D. Van; Sighem, A. Van; Vourli, G.; Zangerle, R.; Porter, K. (2017)
      Background. The Joint United Nations Programme on HIV/AIDS (UNAIDS) has set a "90-90-90" target to curb the human immunodeficiency virus (HIV) epidemic by 2020, but methods used to assess whether countries have reached ...
    • Article  

      Impact of hepatitis B virus infection on the progression of AIDS and mortality in HIV-infected individuals: A cohort study and meta-analysis 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2009)
      Background. The effect of hepatitis B virus (HBV) infection on the natural history of human immunodeficiency virus (HIV) disease remains uncertain. Therefore, a retrospective cohort study was conducted to examine the ...
    • Article  

      Increasing prevalence of HIV-1 subtype a in Greece: Estimating epidemic history and origin 

      Paraskeva, D.; Magiorkinis, Emmanouil; Magiorkinis, Gkikas; Sypsa, V.; Paparizos, V.; Lazanas, Marios; Gargalianos, Panagiotis; Antoniadou, Anastasia; Panos, G.; Chrysos, Georgios; Sambatakou, H.; Karafoulidou, Anastasia; Skoutelis, A.; Kordossis, Theodoros; Koratzanis, Georgios; Theodoridou, M.; Daikos, Georgios L.; Nikolopoulos, Georgios K.; Pybus, O. G.; Hatzakis, A. (2007)
      Background. In North America and Europe, human immunodeficiency virus (HIV)-1 infection has typically been dominated by subtype B transmission. More recently, however, non-B subtypes have been increasingly reported in ...
    • Article  

      Migration and HIV epidemic in Greece 

      Nikolopoulos, Georgios K.; Arvanitis, Michail; Masgala, Aikaterini; Paraskeva, D. (2005)
      Background: Over the last decade, Greece has experienced a massive influx of migrants from countries in South Eastern/Central Europe, the Middle East, Asia and Africa. This study aimed to estimate the percentage and the ...
    • Article  

      National income inequality and declining GDP growth rates are associated with increases in HIV diagnoses among people who inject drugs in Europe: A panel data analysis 

      Nikolopoulos, Georgios K.; Fotiou, Anastasios; Kanavou, Eleftheria; Richardson, C.; Detsis, Marios; Pharris, Anastasia; Suk, J. E.; Semenza, J. C.; Costa-Storti, Claudia; Paraskeva, D.; Sypsa, V.; Malliori-Minerva, Melpomeni; Friedman, Samuel R.; Hatzakis, A. (2015)
      Background: There is sparse evidence that demonstrates the association between macro-environmental processes and drug-related HIV epidemics. The present study explores the relationship between economic, socio-economic, ...