• Article  

      Apoptosis and hepatitis C virus infection in renal transplant recipients 

      Delladetsima, I.; Psichogiou, M.; Alexandrou, P.; Nikolopoulos, Georgios K.; Revenas, K.; Hatzakis, A.; Boletis, J. (2008)
      Hepatocellular injury in renal transplant recipients with hepatitis C virus (HCV) infection remains unclear. The suppressed immune response, in combination with increased viremia levels, provides a unique setting for the ...
    • Article  

      Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme 

      Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)
      Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...
    • Article  

      Economic recession and emergence of an HIV-1 outbreak among drug injectors in Athens metropolitan area: A longitudinal study 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Fotiou, Anastasios; Tsiara, Chrissa G.; Paraskeva, D.; Sypsa, V.; Lazanas, Marios; Gargalianos, Panagiotis; Psichogiou, M.; Skoutelis, A.; Wiessing, L.; Friedman, Samuel R.; Jarlais, Don C. Des; Terzidou, M.; Kremastinou, Jenny; Malliori-Minerva, Melpomeni; Hatzakis, A. (2013)
      Background: During 2011, a dramatic increase (1600%) of reported HIV-1 infections among injecting drug users (IDUs) was noted in Athens, Greece. We herein assess the potential causal pathways associated with this outbreak. ...
    • Article  

      Enhanced HIV-1 surveillance using molecular epidemiology to study and monitor HIV-1 outbreaks among intravenous drug users (IDUs) in Athens and Bucharest 

      Paraskeva, D.; Paraschiv, S.; Sypsa, V.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Magiorkinis, Gkikas; Psichogiou, M.; Flampouris, Andreas; Mardarescu, Mariana; Niculescu, I.; Batan, Ionelia; Malliori-Minerva, Melpomeni; Otelea, D.; Hatzakis, A. (2015)
      Background: A significant increase in HIV-1 diagnoses was reported among Injecting Drug Users (IDUs) in the Athens (17-fold) and Bucharest (9-fold) metropolitan areas starting 2011. Methods: Molecular analyses were conducted ...
    • Article  

      Evaluation of the limiting antigen avidity EIA (LAg) in people who inject drugs in Greece 

      Nikolopoulos, Georgios K.; Katsoulidou, Antigoni; Kantzanou, Maria; Rokka, C.; Tsiara, Chrissa G.; Sypsa, V.; Paraskeva, D.; Psichogiou, M.; Friedman, Samuel R.; Hatzakis, A. (2017)
      This analysis assessed the utility of the limiting antigen avidity assay (LAg). Samples of people who inject drugs (PWID) in Greece with documented duration of HIV-1 infection were tested by LAg. A LAg-normalized optical ...
    • Article  

      HBV-DNA levels predict overall mortality in HIV/HBV coinfected individuals 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Psichogiou, M.; Hatzakis, A. (2016)
      The coinfection of Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) has been associated with increased death rates. However, the relevant research has mostly relied on serologic HBV testing [HBV surface antigen ...
    • Article  

      Homelessness and other risk factors for HIV infection in the current outbreak among injection drug users in Athens, Greece 

      Sypsa, V.; Paraskeva, D.; Malliori-Minerva, Melpomeni; Nikolopoulos, Georgios K.; Panopoulos, A.; Kantzanou, Maria; Katsoulidou, Antigoni; Psichogiou, M.; Fotiou, Anastasios; Pharris, Anastasia; Laar, M. J. van de; Wiessing, L.; Jarlais, Don C. Des; Friedman, Samuel R.; Hatzakis, A. (2015)
      Objectives: We examined HIV prevalence and risk factors among injection drug users (IDUs) in Athens, Greece, during an HIV outbreak. Methods: We used respondent-driven sampling (RDS) to recruit 1404 IDUs to the Aristotle ...
    • Article  

      A network intervention that locates and intervenes with recently HIV-infected persons: The Transmission Reduction Intervention Project (TRIP) 

      Nikolopoulos, Georgios K.; Pavlitina, E.; Muth, Stephen Q.; Schneider, J. A.; Psichogiou, M.; Williams, L. D.; Paraskeva, D.; Sypsa, V.; Magiorkinis, Gkikas; Smyrnov, P.; Korobchuk, Anya; Vasylyeva, T. I.; Skaathun, B.; Malliori-Minerva, Melpomeni; Kafetzopoulos, Evangelos; Hatzakis, A.; Friedman, Samuel R. (2016)
      Early treatment, soon after infection, reduces HIV transmissions and benefits patients. The Transmission Reduction Intervention Project (TRIP) evaluated a network intervention to detect individuals recently infected (in ...
    • Article  

      Prevalence of drug resistance among HIV-1 treatment-naive patients in Greece during 2003–2015: Transmitted drug resistance is due to onward transmissions 

      Paraskeva, D.; Kostaki, Evangelia-Georgia; Magiorkinis, Gkikas; Gargalianos, Panagiotis; Xylomenos, G.; Magiorkinis, Emmanouil; Lazanas, Marios; Chini, M.; Nikolopoulos, Georgios K.; Skoutelis, A.; Papastamopoulos, V.; Antoniadou, Anastasia; Papadopoulos, A.; Psichogiou, M.; Daikos, Georgios L.; Oikonomopoulou, M.; Zavitsanou, A.; Chrysos, Georgios; Paparizos, V.; Kourkounti, S.; Sambatakou, H.; Sipsas, N. V.; Lada, M.; Panagopoulos, P.; Maltezos, E.; Drimis, S.; Hatzakis, A. (2017)
      Background The prevalence of HIV-1 drug resistance among treatment-naïve patients ranges between 8.3% and 15% in Europe and North America. Previous studies showed that subtypes A and B were the most prevalent in the Greek ...
    • Article  

      Rapid Decline in HIV Incidence among Persons Who Inject Drugs during a Fast-Track Combination Prevention Program after an HIV Outbreak in Athens 

      Sypsa, V.; Psichogiou, M.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Paraskeva, D.; Micha, Katerina; Malliori-Minerva, Melpomeni; Pharris, Anastasia; Wiessing, L.; Donoghoe, Martin; Friedman, Samuel R.; Jarlais, Don Des; Daikos, Georgios L.; Hatzakis, A. (2017)
      Background. A "seek-test-treat" intervention (ARISTOTLE) was implemented in response to an outbreak of human immunodeficiency virus (HIV) infection among persons who inject drugs (PWID) in Athens. We assess trends in HIV ...
    • Article  

      Socially-Integrated Transdisciplinary HIV Prevention 

      Friedman, Samuel R.; Jr, M. J. Downing; Smyrnov, P.; Nikolopoulos, Georgios K.; Schneider, J. A.; Livak, B.; Magiorkinis, Gkikas; Slobodianyk, L.; Vasylyeva, T. I.; Paraskeva, D.; Psichogiou, M.; Sypsa, V.; Malliori-Minerva, Melpomeni; Hatzakis, A. (2014)
      Current ideas about HIV prevention include a mixture of primarily biomedical interventions, socio-mechanical interventions such as sterile syringe and condom distribution, and behavioral interventions. This article presents ...