Browsing by Subject "Autism spectrum disorder"

Now showing items 1-7 of 7

    • Article  

      Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers 

      Pramparo, Tiziano; Lombardo,Michael V.; Campbell, Kathleen; Barnes, Cynthia Carter; Marinero, S.; Solso, S.; Young, Julia; Mayo, Maisi; Dale, Anders; Ahrens-Barbeau, Clelia; Murray, Sarah S.; Lopez, Linda; Lewis, Nathan E.; Pierce, Karen; Courchesne, Eric (2015)
      Genetic mechanisms underlying abnormal early neural development in toddlers with Autism Spectrum Disorder (ASD) remain uncertain due to the impossibility of direct brain gene expression measurement during critical periods ...
    • Article  

      The EU-AIMS Longitudinal European Autism Project (LEAP): Clinical characterisation 

      Charman, T.; Loth, Eva; Tillmann, Julian; Crawley, Daisy; Wooldridge, C.; Goyard, David; Ahmad, Jumana; Auyeung, Bonnie; Ambrosino, Sara; Banaschewski, Tobias; Baron-Cohen,Simon; Baumeister, Sarah; Beckmann, Christian; Bölte, Sven; Bourgeron, Thomas; Bours, Carsten; Brammer, Michael; Brandeis, Daniel; Brogna, Claudia; De Bruijn, Y.; Chakrabarti,B.; Cornelissen, Ineke; Acqua, Flavio Dell; Dumas, G.; Durston, Sarah; Ecker,C.; Faulkner, J.; Frouin, Vincent; Garces, Pilar; Ham, Lindsay M.; Hayward, Hannah; Hipp, Joerg; Holt, R. J.; Isaksson, Johan; Johnson, Mark H.; Jones, Emily J. H.; Kundu, Prantik; Lai,Meng-Chuan; D'Ardhuy, X. L.; Lombardo,Michael V.; Lythgoe, David J.; Mandl, Rene; Mason, Luke; Meyer-Lindenberg, Andreas; Moessnang, Carolin; Mueller, Nico; O'Dwyer, Laurence; Oldehinkel, Marianne; Oranje, Bob; Pandina, Gahan J.; Persico, Antonio M.; Ruggeri, B.; Ruigrok,Amber N. V.; Sabet, Jessica; Sacco, Roberto; Caceres, Antonia San Jose; Simonoff, Emily; Toro, Roberto; Tost, Heike; Waldman, Jack; Williams,Steven C. R.; Zwiers, Marcel P.; Spooren, Will; Murphy,Declan G. M.; Buitelaar, Jan K. (2017)
      Background: The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). The current paper describes ...
    • Article  

      Frontal networks in adults with autism spectrum disorder 

      Catani, Marco; Dell’Acqua, Flavio; Budisavljevic, Sanja; Howells, Henrietta; Schotten, Thiebaut De; Froudist-Walsh, Sean; D'Anna, Lucio; Thompson, A.; Sandrone, Stefano; Bullmore,Edward T.; Suckling,John; Baron-Cohen,Simon; Lombardo,Michael V.; Wheelwright,Sally J.; Chakrabarti,B.; Lai,Meng-Chuan; Ruigrok,Amber N. V.; Leemans, Alexander; Ecker,C.; Craig, Michael C.; Murphy,Declan G. M.; Bailey, Anthony J.; Bolton, P. F.; Carrington, S.; Daly,Eileen M.; Deoni,Sean C. L.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Ruigrok,Amber N. V.; Sadek,Susan A.; Spain,D.; Stewart, R.; Williams,Steven C. R. (2016)
      It has been postulated that autism spectrum disorder is underpinned by an 'atypical connectivity' involving higher-order association brain regions. To test this hypothesis in a large cohort of adults with autism spectrum ...
    • Article  

      The neuropsychology of male adults with high-functioning autism or asperger syndrome 

      Wilson, C. E.; Happé,Francesca; Wheelwright,Sally J.; Ecker,C.; Lombardo,Michael V.; Johnston,Patrick; Daly,Eileen M.; Murphy,Clodagh M.; Spain,D.; Lai,Meng-Chuan; Chakrabarti,B.; Sauter, Disa A.; Baron-Cohen,Simon; Murphy,Declan G. M. (2014)
      Autism Spectrum Disorder (ASD) is diagnosed on the basis of behavioral symptoms, but cognitive abilities may also be useful in characterizing individuals with ASD. One hundred seventy-eight high-functioning male adults, ...
    • Article  

      Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? 

      Cadman, T.; Spain,D.; Johnston,Patrick; Russell, A.; Mataix-Cols, D.; Craig, Michael C.; Deeley, Q.; Robertson, D. M.; Murphy,Clodagh M.; Gillan, N.; Wilson, C. E.; Mendez, M.; Ecker,C.; Daly,Eileen M.; Findon, J.; Glaser, K.; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Chakrabarti,B.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Steward, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R.; Happé,Francesca; Murphy,Clodagh M. (2015)
      Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD ...
    • Article  

      On the brain structure heterogeneity of autism: Parsing out acquisition site effects with significance-weighted principal component analysis 

      Martinez-Murcia, Francisco; Lai,Meng-Chuan; Górriz, Juan Manuel; Ramirez, Javier; Young, Adam M. H.; Deoni,Sean C. L.; Ecker,C.; Lombardo,Michael V.; MRC AIMS Consortium; Baron-Cohen,Simon; Murphy,Declan G. M.; Bullmore,Edward T.; Suckling,John; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Catani, Marco; Chakrabarti,B.; Craig, Michael C.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lai,Meng-Chuan; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Ruigrok,Amber N. V.; Sadek,Susan A.; Spain,D.; Stewart, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R. (2017)
      Neuroimaging studies have reported structural and physiological differences that could help understand the causes and development of Autism Spectrum Disorder (ASD). Many of them rely on multisite designs, with the recruitment ...
    • Article  

      Relationship between cortical gyrification, white matter connectivity, and autism spectrum disorder 

      Ecker,C.; Andrews, Derek Sayre; Dell’Acqua, Flavio; Daly,Eileen M.; Murphy,Clodagh M.; Catani, Marco; Schotten, Thiebaut De; Baron-Cohen,Simon; Lai,Meng-Chuan; Lombardo,Michael V.; Bullmore,Edward T.; Suckling,John; Williams,Steven C. R.; Jones, D. K.; Chiocchetti, A.; Murphy,Declan G. M. (2016)
      Autism spectrum disorder (ASD) is a complex neurodevelopmental condition, which is accompanied by differences in gray matter neuroanatomy and white matter connectivity. However, it is unknown whether these differences are ...