Browsing by Subject "Cancer"

Now showing items 1-20 of 51

    • Article  

      Anxiety, depression and defense mechanisms associated with treatment decisional preferences and quality of life in non-metastatic breast cancer: A 1-year prospective study 

      Hyphantis, T.; Almyroudi, A.; Paika, V.; Degner, L. F.; Carvalho, A. F.; Pavlidis, Nicholas (2013)
      Objective: Treatment decisional preferences impact breast cancer patients' health-related quality of life (HRQoL) and may relate to psychological variables, although many aspects of this relationship remain unknown. This ...
    • Article  

      Bone and soft tissue sarcomas during pregnancy: A narrative review of the literature 

      Zarkavelis, George; Petrakis, Dimitrios; Fotopoulos, George; Mitrou, Sotirios; Pavlidis, Nicholas (2016)
      Bone or soft tissue sarcomas are rarely diagnosed during pregnancy. Until today 137 well documented cases have been reported in the English literature between 1963 and 2014. Thirty-eight pregnant mothers were diagnosed ...
    • Article  

      Cancer and pregnancy: A comprehensive review 

      Voulgaris, E.; Pentheroudakis, George; Pavlidis, Nicholas (2011)
      Background: Pregnancy complicated by cancer is relatively rare but, as women in western societies tend to delay childbearing to the third and fourth decade of life, this phenomenon is going to be encountered more often in ...
    • Article  

      Cancer and pregnancy: Poena magna, not anymore 

      Pentheroudakis, George; Pavlidis, Nicholas (2006)
      Cancer diagnosed during pregnancy constitutes a difficult clinical condition with a devastating impact on the patient's somatic and psychosocial health and possibly on foetal integrity. This circumstance also raises several ...
    • Article  

      Cancer of unknown primary (CUP) 

      Pavlidis, Nicholas; Fizazi, K. (2005)
      Carcinoma of unknown primary (CUP) is one of the 10 most frequent cancers worldwide. It constitutes 3-5% of all human malignancies. Patients with CUP present with metastases without an established primary site. CUP manifests ...
    • Article  

      Cancer of unknown primary site: Missing primary or missing biology? 

      Pentheroudakis, George; Briassoulis, E. Ch; Pavlidis, Nicholas (2007)
      Cancer of unknown primary site (CUP) ranks as the fourth most common cause of cancer deaths and represents both a diagnostic and a management challenge. In CUP, the regression or dormancy of the primary tumor, the development ...
    • Article  

      Cancer prevalence and mortality in centenarians: A systematic review 

      Pavlidis, Nicholas; Stanta, G.; Audisio, R. A. (2012)
      Life expectancy has dramatically expanded, the global population has aged unprecedentedly and the number of centenarians has significantly increased. The analysis of autopsy series, cancer registries data, vital statistics ...
    • Article  

      Coexistence of pregnancy and malignancy 

      Pavlidis, Nicholas (2002)
      Cancer complicating pregnancy is a rare coexistence. The incidence is approximately 1 in 1,000 pregnancies. The most common cancers are those more frequently seen during the reproductive age of a woman. Breast cancer, ...
    • Article  

      A compendium of volatile organic compounds (VOCs) released by human cell lines 

      Filipiak, W.; Mochalski, Paweł; Filipiak, A.; Ager, C.; Cumeras, R.; Davis, C. E.; Agapiou, Agapios; Unterkofler, K.; Troppmair, J. (2016)
      Volatile organic compounds (VOCs) offer unique insights into ongoing biochemical processes in healthy and diseased humans. Yet, their diagnostic use is hampered by the limited understanding of their biochemical or cellular ...
    • Article  

      Depression in cancer: The many biobehavioral pathways driving tumor progression 

      Bortolato, B.; Hyphantis, T.; Valpione, S.; Perini, G.; Maes, M.; Morris, G.; Kubera, M.; Köhler, C. A.; Fernandes, B. S.; Stubbs, B.; Pavlidis, Nicholas; Carvalho, A. F. (2017)
      Major Depressive Disorder (MDD) is common among cancer patients, with prevalence rates up to four-times higher than the general population. Depression confers worse outcomes, including non-adherence to treatment and increased ...
    • Article  

      Diagnostic and therapeutic management of cancer of an unknown primary 

      Pavlidis, Nicholas; Briassoulis, E. Ch; Hainsworth, J.; Greco, F. A. (2003)
      Metastatic Cancer of Unknown Primary Site (CUP) accounts for approximately 3% of all malignant neoplasms and is therefore one of the 10 most frequent cancer diagnoses in man. Patients with CUP present with metastatic disease ...
    • Article  

      The ESMO guideline strategy: An identity statement and reflections on improvement 

      Pentheroudakis, George; Cardoso, Fatima; Arnold, D.; Sessa, Cristiana; Peters, S.; Horwich, A.; Pavlidis, Nicholas; Stahel, R. A.; Cervantes, A. (2015)
      Guidelines should provide recommendations on the optimal management of a patient in specific clinical circumstances based on the scientific evidence. ESMO, as Europe's leading society in medical oncology produces a range ...
    • Article  

      ESMO minimum clinical recommendations - The beginning of a process 

      Stahel, R. A.; Purkalne, Gunta; Herrstedt, J.; Jelic, S.; Fervers, B.; Kloke, O.; Mellstedt, H.; Pavlidis, Nicholas; Jost, Lorenz M. (2001)
    • Article  

      ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of cancers of unknown primary site (CUP) 

      Briassoulis, E. Ch; Ch, F. Tolis; Pavlidis, Nicholas (2001)
    • Article  

      Essential drugs for cancer chemotherapy 

      Advani, S.; Friedman, M. A.; Henderson, I. C.; Levy, L. M.; Pavlidis, Nicholas; Tattersall, M. H. N.; Couper, M. R.; Dunne, J. F.; Korobchuk, Anya; Stjernsward, J. (1994)
      The WHO recommendation on essential drugs for cancer chemotherapy has been updated. General principles on the proper role of cancer chemotherapeutic agents in relation to efficacy and on the classification of tumours with ...
    • Article  

      Exploring the nano-surface of collagenous and other fibrotic tissues with AFM 

      Stylianou, A.; Gkretsi, V.; Patrickios, Costas S.; Stylianopoulos, Triantafyllos (2017)
      Atomic force microscope (AFM) is a powerful and invaluable tool for imaging and probing the mechanical properties of biological samples at the nanometric scale. The importance of nano-scale characterization and nanomechanics ...
    • Article  

      Exploring the nano-surface of collagenous and other fibrotic tissues with AFM 

      Stylianou, A.; Gkretsi, V.; Patrickios, C. S.; Stylianopoulos, T. (2017)
      Atomic force microscope (AFM) is a powerful and invaluable tool for imaging and probing the mechanical properties of biological samples at the nanometric scale. The importance of nano-scale characterization and nanomechanics ...
    • Article  

      Heterogeneity in cancer guidelines: Should we eradicate or tolerate? 

      Pentheroudakis, George; Stahel, R. A.; Hansen, H.; Pavlidis, Nicholas (2008)
      Background: Heterogeneity in aspects of development, structure and context of oncology guidelines was not evaluated. We analysed and critically examined its implications. Materials and methods: Nine cancer clinical practice ...
    • Doctoral Thesis  Open Access

      In vitro investigation of the role of Ras Suppressor-1 (RSU-1) and Integrin-Linked kinase (ILK) in glioma progression and invasion 

      Louca, Maria A. (Πανεπιστήμιο Κύπρου, Πολυτεχνική Σχολή / University of Cyprus, Faculty of Engineering, 2019-12)
      Το πολύμορφο γλοιοβλάστωμα (Glioblastoma multiforme-GBM) είναι ο πιο επιθετικός τύπος καρκίνου του εγκεφάλου λόγω της ικανότητας των κυττάρων του να διεισδύουν σε γειτονικούς ιστούς. H μέση επιβίωση για τους ασθενείς είναι ...
    • Article  

      Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 

      Oppedisano, F.; Catto, M.; Koutentis, Panayiotis Andreas; Nicolotti, O.; Pochini, L.; Koyioni, Maria G.; Introcaso, A.; Michaelidou, Sophia S.; Carotti, A.; Indiveri, C. (2012)
      The ASCT2 transport system catalyses a sodium-dependent antiport of glutamine and other neutral amino acids which is involved in amino acid metabolism. A library of 1,2,3-dithiazoles was designed, synthesized and evaluated ...