• Article  

      Delta-like and Gtl2 are reciprocally expressed differentially methylated linked imprinted genes on mouse chromosome 12 

      Takada, S.; Tevendale, M.; Baker, J.; Georgiades, Pantelis; Campbell, E.; Freeman, T.; Johnson, M. H.; Paulsen, M.; Ferguson-Smith, A. C. (2000)
      The distal portion of mouse chromosome 12 is imprinted. To date, however, Gtl2 is the only imprinted gene identified on chromosome 12. Gtl2 encodes multiple alternatively spliced transcripts with no apparent open reading ...
    • Doctoral Thesis  Open Access

      Identification and characterization of fetal specific methylated regions for non-invasive prenatal diagnosis 

      Ioannides, Marios S. (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2014-12)
      Η προγεννητική διάγνωση έχει ως σκοπό τη διάγνωση των πιο κοινών εμβρυικών ανευπλοειδιών και ανωμαλιών. Σήμερα, ο μη επεμβατικός έλεγχος προσφέρεται σε όλες τις κυήσεις παρέχοντας ένα ρίσκο κινδύνου εμφάνισης των πιο ...
    • Article  

      The Polycomb Group Protein SUZ12 regulates histone H3 lysine 9 methylation and HP1α distribution 

      De La Cruz, C. C.; Kirmizis, Antonis; Simon, M. D.; Isono, K. -I; Koseki, H.; Panning, B. (2007)
      Regulation of histone methylation is critical for proper gene expression and chromosome function. Suppressor of Zeste 12 (SUZ12) is a requisite member of the EED/EZH2 histone methyltransferase complexes, and is required ...