Browsing by Subject "Nucleophilic aromatic substitution"
Now showing items 1-3 of 3
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Article
Reactions of selected 3-bromoisothiazole-5-carbonitriles with the secondary dialkylamines pyrrolidine and morpholine
(2014)Readily available 3-bromoisothiazole-5-carbonitriles bearing various C-4 substituents [H, CO2R C[tbnd]N and halogen (Cl or Br)], react with either pyrrolidine or morpholine to give, in most cases, the 3-amino-substituted ...
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Article
Route to benzo- and pyrido-fused 1,2,4-triazinyl radicals via N ′-(Het)aryl- N ′-[2-nitro(het)aryl]hydrazides
(2014)A two-step route to 1,3-disubstituted benzo- and pyrido-fused 1,2,4-triazinyl radicals is presented. The route involves the N′-(2-nitroarylation) of easily prepared N′-(het)arylhydrazides via nucleophilic aromatic substitution ...
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Article
Substitution chemistry of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals
(2016)The reactivity of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals towards nucleophilic substitution or palladium-catalyzed C–C coupling at the C-3/5 positions led to seven new 3,5-disubstituted 4H-1,2,6-thiadiazine ethylene ...