Browsing by Subject "Oncogenes"

Now showing items 1-5 of 5

    • Article  

      Cancer of unknown primary site: Missing primary or missing biology? 

      Pentheroudakis, George; Briassoulis, E. Ch; Pavlidis, Nicholas (2007)
      Cancer of unknown primary site (CUP) ranks as the fourth most common cause of cancer deaths and represents both a diagnostic and a management challenge. In CUP, the regression or dormancy of the primary tumor, the development ...
    • Doctoral Thesis  Open Access

      The human papillomavirus E7 oncoprotein affects the activity of Oct4 in cervical cancer 

      Panayiotou, Theofano I. (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-12)
      Ο μεταγραφικός παράγοντας Oct4 διαδραματίζει σαφείς ρόλους στην εμβρυ?κή ανάπτυξη και σχετίζεται με την πολυδυναμία των κυττάρων. Πρόσφατα, οι λειτουργίες του έχουν ταυτιστεί και με την καρκινογένεση. Παρόλα αυτά, η ...
    • Article  

      Overexpression of C-myc, ras and C-erb B-2 oncoproteins in carcinoma of unknown primary origin 

      Pavlidis, Nicholas; Briassoulis, E. Ch; Bai, M. C.; Fountzilas, George; Agnantis, Niki J. (1995)
      The role of oncogenes in carcinoma of unknown primary site (CUP) has not yet been elucidated. In the present study the expression of the c-myc p62, ras p21 and c-erb B p185 oncoproteins were studied by a 3-step immunoperoxidase ...
    • Article  

      Perspectives for targeted therapies in cancer of unknown primary site 

      Pentheroudakis, George; Pavlidis, Nicholas (2006)
      Cancer of unknown primary site (CUP) ranks as the fourth most common cause of cancer deaths. Regression of the primary, early development of systemic metastases and resistance to therapy are hallmarks of this heterogeneous ...
    • Article  

      Role of Rb-dependent and Rb-independent functions of papillomavirus E7 oncogene in head and neck cancer 

      Strati, Katerina; Lambert, P. F. (2007)
      Infection with high-risk human papillomaviruses (HPV) and in particular the expression of the viral proteins E6 and E7 have been associated with the etiology of a subset of head and neck squamous cell cancer (HNSCC). ...