Browsing by Subject "genome"

Now showing items 1-2 of 2

    • Article  

      Balanced translocations for the analysis of imprinted regions of the mouse genome. 

      Ferguson-Smith, A. C.; Tevendale, M.; Georgiades, Pantelis; Grandjean, V. (2001)
      Experimental studies that investigate the functional and mechanistic properties of an imprinted locus require material in which the two parental chromosome homologs can be easily distinguished. The use of animals with ...
    • Article  

      A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity 

      Marión, R. M.; Strati, Katerina; Li, H.; Murga, M.; Blanco, R.; Ortega, S.; Fernandez-Capetillo, O.; Serrano, M.; Blasco, M. A. (2009)
      The reprogramming of differentiated cells to pluripotent cells (induced pluripotent stem (iPS) cells) is known to be an inefficient process. We recently reported that cells with short telomeres cannot be reprogrammed to ...