Browsing by Subject "neovascularization (pathology)"
Now showing items 1-4 of 4
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Article
Role of vascular normalization in benefit from metronomic chemotherapy
(2017)Metronomic dosing of chemotherapy - defined as frequent administration at lower doses - has been shown to be more efficacious than maximum tolerated dose treatment in preclinical studies, and is currently being tested in ...
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Article
The Solid Mechanics of Cancer and Strategies for Improved Therapy
(2017)Tumor progression and response to treatment is determined in large part by the generation of mechanical stresses that stem from both the solid and the fluid phase of the tumor. Furthermore, elevated solid stress levels can ...
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Article
A Validated Multiscale In-Silico Model for Mechano-sensitive Tumour Angiogenesis and Growth
(2017)Vascularisation is a key feature of cancer growth, invasion and metastasis. To better understand the governing biophysical processes and their relative importance, it is instructive to develop physiologically representative ...
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Article
Why one-size-fits-all vaso-modulatory interventions fail to control glioma invasion: In silico insights
(2016)Gliomas are highly invasive brain tumours characterised by poor prognosis and limited response to therapy. There is an ongoing debate on the therapeutic potential of vaso-modulatory interventions against glioma invasion. ...