Browsing by Subject "stroma cell"
Now showing items 1-5 of 5
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Atomic Force Microscopy Probing of Cancer Cells and Tumor Microenvironment Components
(2016)Cancer cells have different characteristics from normal cells in terms of morphology, cell–cell interactions, cytoskeleton organization, cell growth rates, and cell-extracellular matrix interactions. Although the clarification ...
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Defining the role of solid stress and matrix stiffness in cancer cell proliferation and metastasis
(2018)Solid tumors are characterized by an abnormal stroma that contributes to the development of biomechanical abnormalities in the tumor microenvironment. In particular, these abnormalities include an increase in matrix stiffness ...
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Novel spatiotemporal glycome changes in the murine placenta during placentation based on BS-I lectin binding patterns
(2013)Although spatiotemporal changes of the glycome (full set of glycans, otherwise known as saccharides or carbohydrates) during placenta formation (placentation) are functionally and clinically important, they are poorly ...
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Remodeling components of the tumor microenvironment to enhance cancer therapy
(2015)Solid tumor pathophysiology is characterized by an abnormal microenvironment that guides tumor progression and poses barriers to the efficacy of cancer therapies. Most common among tumor types are abnormalities in the ...
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Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo- and nanotherapy
(2017)Targeting the rich extracellular matrix of desmoplastic tumors has been successfully shown to normalize collagen and hyaluronan levels and re-engineer intratumoral mechanical forces, improving tumor perfusion and chemotherapy. ...