Browsing by Subject "telomere"
Now showing items 1-2 of 2
-
Article
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
(2009)The reprogramming of differentiated cells to pluripotent cells (induced pluripotent stem (iPS) cells) is known to be an inefficient process. We recently reported that cells with short telomeres cannot be reprogrammed to ...
-
Article
Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells
(2009)Telomere shortening is associated with organismal aging. iPS cells have been recently derived from old patients