Browsing by Subject "theoretical model"
Now showing items 1-15 of 15
-
Article
Cationic nanoparticles have superior transvascular flux into solid tumors: Insights from a mathematical model
(2013)Despite their great promise, only a few nanoparticle formulations have been approved for clinical use in oncology. The failure of nano-scale drugs to enhance cancer therapy is in large part due to inefficient delivery. To ...
-
Article
Comparison of three-jet events in pp̄ collisions at √s = 1.8 TeV to predictions from a next-to-leading order QCD calculation
(2005)The properties of three-jet events with total transverse energy greater than 320 GeV and individual jet energy greater than 20 GeV have been analyzed and compared to absolute predictions from a next-to-leading order (NLO) ...
-
Article
Fluctuations in biological and bioinspired electron-transfer reactions
(2010)Central to theories of electron transfer (ET) is the idea that nuclear motion generates a transition state that enables electron flow to proceed, but nuclear motion also induces fluctuations in the donor-acceptor (DA) ...
-
Article
Island species richness increases with habitat diversity
(2009)Species richness is commonly thought to increase with habitat diversity. However, a recent theoretical model aiming to unify niche and island biogeography theories predicted a hump-shaped relationship between richness and ...
-
Article
Long-range charge transport in single G-quadruplex DNA molecules
(2014)DNA and DNA-based polymers are of interest in molecular electronics because of their versatile and programmable structures. However, transport measurements have produced a range of seemingly contradictory results due to ...
-
Article
Prediction of blood:air and fat:Air partition coefficients of volatile organic compounds for the interpretation of data in breath gas analysis
(2016)In this article, a database of blood:air and fat:air partition coefficients (λ b:a and λ f:a) is reported for estimating 1678 volatile organic compounds recently reported to appear in the volatilome of the healthy human. ...
-
Article
Remodeling of extracellular matrix due to solid stress accumulation during tumor growth
(2015)Solid stresses emerge as the expanding tumor displaces and deforms the surrounding normal tissue, and also as a result of intratumoral component interplay. Among other things, solid stresses are known to induce extensive ...
-
Article
The role of mechanical forces in tumor growth and therapy
(2014)Tumors generate physical forces during growth and progression. These physical forces are able to compress blood and lymphatic vessels, reducing perfusion rates and creating hypoxia. When exerted directly on cancer cells, ...
-
Article
Role of vascular normalization in benefit from metronomic chemotherapy
(2017)Metronomic dosing of chemotherapy - defined as frequent administration at lower doses - has been shown to be more efficacious than maximum tolerated dose treatment in preclinical studies, and is currently being tested in ...
-
Book Chapter
Skill shortages and structural unemployment in Britain: a (mis) matching approach
(Cambridge University Press, 1991)Invokes microeconomic evidence on the nature of British unemployment and its causes, and investigates the thesis that much of its increase during the late 1970s and early 1980s can be attributed to the mismatch of different ...
-
Article
The Solid Mechanics of Cancer and Strategies for Improved Therapy
(2017)Tumor progression and response to treatment is determined in large part by the generation of mechanical stresses that stem from both the solid and the fluid phase of the tumor. Furthermore, elevated solid stress levels can ...
-
Article
Tensile mechanical properties and hydraulic permeabilities of electrospun cellulose acetate fiber meshes.
(2012)The mechanical properties and hydraulic permeabilities of biomaterial scaffolds play a crucial role in their efficacy as tissue engineering platforms, separation processors, and drug delivery vehicles. In this study, ...
-
Article
The trapped human experiment
(2011)This experiment observed the evolution of metabolite plumes from a human trapped in a simulation of a collapsed building. Ten participants took it in turns over five days to lie in a simulation of a collapsed building and ...
-
Article
Unemployment consequences of an aging population: An application of insider-outsider theory
(1989)
-
Article
Vibrational control of electron-transfer reactions: A feasibility study for the fast coherent transfer regime
(2015)Molecular vibrations and electron-vibrational interactions are central to the control of biomolecular electron and energy-transfer rates. The vibrational control of molecular electron-transfer reactions by infrared pulses ...