Browsing by Subject "tumor suppressor protein"

Now showing items 1-3 of 3

    • Article  

      The Ink4/Arf locus is a barrier for iPS cell reprogramming 

      Li, H.; Collado, M.; Villasante, A.; Strati, Katerina; Ortega, S.; Cãamero, M.; Blasco, M. A.; Serrano, M. (2009)
      The mechanisms involved in the reprogramming of differentiated cells into induced pluripotent stem (iPS) cells by the three transcription factors Oct4 (also known as Pou5f1), Klf4 and Sox2 remain poorly understood. The ...
    • Article  

      Shared mechanisms in stemness and carcinogenesis: Lessons from oncogenic viruses 

      Iacovides, D.; Michael, S.; Achilleos, Charis; Strati, Katerina (2013)
      A rise in technologies for epigenetic reprogramming of cells to pluripotency, highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared ...
    • Article  

      Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis 

      Papageorgis, P.; Ozturk, S.; Lambert, A. W.; Neophytou, Christiana M.; Tzatsos, Alexandros; Wong, C. K.; Thiagalingam, S.; Constantinou, Andreas I. (2015)
      Introduction: Basal-like breast cancer (BLBC) is an aggressive subtype often characterized by distant metastasis, poor patient prognosis, and limited treatment options. Therefore, the discovery of alternative targets to ...