Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Title
Now showing items 377-396 of 677
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Article
Magnetic resonance spectroscopy of live drosophila melanogaster using magic angle spinning
(2010)High-Resolution Magic Angle Spinning (HRMAS) proton magnetic resonance spectroscopy (1H-MRS) is a novel non-destructive technique that improves spectral line-widths and allows high-resolution spectra to be obtained from ...
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Article
Magnetic resonance spectroscopy of live Drosophila melanogaster using magic angle spinning.
(2010)High-Resolution Magic Angle Spinning (HRMAS) proton magnetic resonance spectroscopy ((1)H-MRS) is a novel non-destructive technique that improves spectral line-widths and allows high-resolution spectra to be obtained from ...
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Article
Making the Connection: Ciliary Adhesion Complexes Anchor Basal Bodies to the Actin Cytoskeleton
(2014)Cilia have been associated with diverse developmental and physiological processes, and defects in cilia underlie a number of genetic conditions. Several lines of evidence support a critical role of the actin cytoskeleton ...
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Article
A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis
(2013)Background: The unfolded protein response (UPR) is a major signalling cascade acting in the quality control of protein folding in the endoplasmic reticulum (ER). The cascade is known to play an accessory role in a range ...
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Article
Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapy
(1999)The role of the thymus in HIV-1 pathogenesis remains unclear. We developed an assay to quantify the number of recent thymic emigrants in blood based on the detection of a major excisional DNA byproduct (termed α1 circle) ...
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Article
Medullary cystic kidney disease type 1: Mutational analysis in 37 genes based on haplotype sharing
(2006)Medullary cystic kidney disease type 1 (MCKD1) is an autosomal dominant, tubulo-interstitial nephropathy that causes renal salt wasting and end-stage renal failure in the fourth to seventh decade of life. MCKD1 was localized ...
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Article
Medullary cystic kidney disease with hyperuricemia and gout in a large Cypriot family: No allelism with nephronophthisis type 1
(1998)We describe a large Cypriot family with an interstitial type of nephropathy, inherited as an autosomal dominant trait that led to end stage renal failure between 51 to 78 years of age (mean 62.2 years). Twenty-three people ...
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Article
Meet the editorial board members
(2015)
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Article
Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila
(2009)Visualizing developing organ formation as well as progession and treatment of disease often heavily relies on the ability to optically interrogate molecular and functional changes in intact living organisms. Most existing ...
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Article
Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila.
(2009)Visualizing developing organ formation as well as progession and treatment of disease often heavily relies on the ability to optically interrogate molecular and functional changes in intact living organisms. Most existing ...
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Article
Metabolic output defines Escherichia coli as a health-promoting microbe against intestinal Pseudomonas aeruginosa
(2019)Gut microbiota acts as a barrier against intestinal pathogens, but species-specific protection of the host from infection remains relatively unexplored. Although lactobacilli and bifidobacteria produce beneficial lactic ...
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Article
A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines
(2000)Estrogen replacement therapy has been correlated with an increased risk of developing breast or endometrial cancer. 4-Hydroxyequilenin (4-OHEN) is a catechol metabolite of equilenin which is a minor component of the estrogen ...
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Book Chapter
Methods of Calpain Inhibition to Determine the Role of Calpains in Embryo Development in Amphibians
(Springer, 2019)Calpains are a family of calcium-dependent intracellular cysteine proteases that regulate important physiological processes by substrate cleavage. Despite the fact that the role of calpains in cell migration and other ...
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Article
MicroRNAs: A newly described class of encoded molecules that play a role in health and disease
(2010)14(4): 236-240.
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Article
A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy
(2012)Heparin binding epidermal growth factor (HBEGF) is expressed in podocytes and was shown to play a role in glomerular physiology. MicroRNA binding sites on the 3′UTR of HBEGF were predicted using miRWalk algorithm and ...
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Article
Mitochondrial sequences of the extinct Cypriot pygmy hippopotamus confirm its phylogenetic placement
(Oxford Academic, 2021-11-19)The Cypriot pygmy hippopotamus is an extinct Mediterranean species that inhabited the island of Cyprus during the Late Pleistocene. This iconic species last appears at the archaeological site of Akrotiri Aetokremnos, dated ...
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Book
Model organisms in inflammation and cancer
(Frontiers Media SA, 2014)
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Article
Model-based tumor growth dynamics and therapy response in a mouse model of de novo carcinogenesis
(2015)Tumorigenesis is a complex, multistep process that depends on numerous alterations within the cell and contribution from the surrounding stroma. The ability to model macroscopic tumor evolution with high fidelity may ...
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Article
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Article
Modelling the role of alien species and fisheries in an Eastern Mediterranean insular shelf ecosystem
(2019)We developed a trophic mass-balance model to describe the structure and functioning of the insular shelf ecosystem of the Republic of Cyprus and assess the impact of fishing and alien species during the mid-2010s. A total ...