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Molecular subtypes and emerging therapeutic opportunities
(Future Medicine, 2011)
Comparative Immunohistochemical Study of Ras-P21 Oncoprotein in Adenomatous Hyperplasia and Adenocarcinoma of the Prostate-Gland
(1994)
The present study assessed the immunohistochemical expression of ras p21 oncoprotein in 41 cases of benign and cancerous lesions of the prostate gland and correlated p21 expression with survival of patients operated for ...
Trastuzumab beyond progression in HER2-positive advanced breast cancer: The Royal Marsden experience
(2011)
BACKGROUND: Recent UK clinical guidance advises against continuing trastuzumab (T) beyond disease progression (PD) in the absence of brain metastases in patients with HER-2 positive (+ ve) advanced breast cancer. We have ...
Advanced soft-tissue sarcoma and treatment options: Critical appraisal of trabectedin
(2016)
Soft-tissue sarcomas (STS) are a heterogeneous group of rare solid tumors of mesenchymal origin. This paper reviews the current status of systemic treatment in advanced and metastatic soft tissue sarcomas, with an emphasis ...
Synovial Sarcoma of the Thyroid Gland, Diagnostic Pitfalls and Clinical Management
(2018)
BACKGROUND/AIM: Synovial sarcoma is a soft tissue sarcoma that tends to affect young adults. There are few reports on primary synovial sarcoma of the thyroid and the aim of this study was to document the clinical and ...
Trabectedin in advanced synovial sarcomas: A multicenter retrospective study from four European institutions and the Italian Rare Cancer Network
(2015)
Treatment options for patients with metastatic synovial sarcoma are limited. Over recent years, trabectedin has emerged as an effective agent for patients with advanced soft tissue sarcomas resistant to anthracyclines and ...