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Studies on the survival of simultaneous canine renal and segmental pancreatic allografts
(1982)
Prolonged survival of the vascularized free-draining intraperitoneal pancreatic segmental allografts (FDPS) has been observed previously in immunosuppressed beagle littermates matched for low mixed lymphocyte culture (MLC) ...
Responses of canine lymphocytes to allogeneic and autologous islets of Langerhans in mixed cell cultures
(1981)
Because successful allotransplantation of islets of Langerhans isolated by collagenase digestion has been difficult in many animal species, we asked whether isolated islet preparations might have tissue specific determinants ...
In vitro generation of human mixed lymphocyte culture suppressor cells: I. Cellular characterization and specificity
(1980)
The mixed leukocyte culture (MLC) of peripheral blood lymphocytes (PBLs) from two prospective kidney transplant recipients and their respective donors, produced a primed cell population that functioned as suppressors. The ...
Kidney transplantation by use of splenectomy and transfusions, cadaver haplotype matching, suppressor cell assays, and T-cell monitoring
(1981)
We attempted to modulate several determinants of the host immunologic profile to improve kidney transplant survival: (1) genotype matching of the cadaver donor with the recipient, (2) assessment in recipients of living ...
Long-term follow-up of renal transplant recipients using immunologic monitoring
(1979)
Since 1972, we have transplanted a total of 79 patients at the Minneapolis VA Hospital, 75 of which were monitored using at least one of several immune assays both pre- and postoperatively. The present report is on a longer ...
Factors affecting the autologous mixed lymphocyte reaction in kidney transplantation
(1983)
In long-term well adapted kidney transplant recipients we have found a close correlation between the T helper (T(H)):T suppressor/cytotoxic (T(S/C)) subset ratios and the presence of T cells that respond in the autologous ...