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A method for large-scale, high-yield isolation of canine pancreatic islets of Langerhans
(1982)
A modified collagenase digestion method is described for the isolation of large numbers of islets from the canine pancreas ( 3500 islets/g). The islets isolated by this technique remained viable and released insulin in ...
Intraperitoneal segmental pancreatic allografts with unligated duct in dogs: The role of histocompatibility for long-term survival
(1981)
In the present work we performed pancreatic transplantation in beagles with defined histocompatibilities in order to study (A) immunogenetic factors affecting pancreatic allograft survival and (B) the functional and ...
Studies on the survival of simultaneous canine renal and segmental pancreatic allografts
(1982)
Prolonged survival of the vascularized free-draining intraperitoneal pancreatic segmental allografts (FDPS) has been observed previously in immunosuppressed beagle littermates matched for low mixed lymphocyte culture (MLC) ...
Responses of canine lymphocytes to allogeneic and autologous islets of Langerhans in mixed cell cultures
(1981)
Because successful allotransplantation of islets of Langerhans isolated by collagenase digestion has been difficult in many animal species, we asked whether isolated islet preparations might have tissue specific determinants ...
Long-term study of vascularized free-draining intraperitoneal pancreatic segmental allografts in beagle dogs
(1981)
The purpose of the present study was to evaluate the significance of immunogenetic factors on the survival of pancreatic allografts in beagle dogs. Donors and recipients were leukocyte antigen (DLA)-typed and mixed lymphocyte ...
Long-term follow-up of canine segmental pancreatic autografts
(1985)
The functional and morphologic characteristics of free-draining, pancreatic segmental autografts (FDPS) were studied in 8 beagle dogs that had survived longer than 4 yr. After pancreatectomy, animals received FDPS autografts ...
Responses of canine lymphocytes to allogeneic and autologous islets of Langerhans in mixed cell cultures
(1981)
Collagenase-isolated islets might possess specific antigens that might lead to unique alloimmune reactions following islet transplantation. In this report, we have examined lymphocyte immune recognition in vitro, i.e., the ...