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Cytotoxic activity of interferon-treated macrophages studied by various inhibitors
(1978)
The ability of interferon-treated macrophages to kill or inhibit the growth of tumor cells is markedly influenced by the local environment. The macrophage cytotoxic effector system is regulated by serum and other environmental ...
Macrophage activation and antitumor activity of a Brucella abortus ether extract, Bru-Pel
(1978)
Bru-Pel and Brucella abortus lipopolysaccharide (LPS) were tested for both macrophage activation and antitumor activity in an artificial metastasis model. Resting macrophages were rendered nonspecifically tumoricidal for ...
Effect of maleic anhydride-divinyl ether copolymers on experimental M109 metastases and macrophage tumoricidal function
(1978)
Pyran copolymer (NSC-46015) was compared with five maleic anhydride-divinyl ether copolymers (MVEs) of narrow molecular weight range both for the ability to render macrophages nonspecifically tumoricidal and to retard the ...
Effects of adriamycin and cyclophosphamide treatment on induction of macrophage cytotoxic function in mice
(1979)
The effects of i.p. and s.c. Adriamycin and cyclophosphamide treatment of BALB/c x DBA/2F1 mice were studied alone and in combination with immunotherapeutic agents, pyran copolymer and Bacillus Calmette-Guérin, on macrophage ...
Regulation of macrophage tumoricidal function: a role for prostaglandins of the E series
(1978)
Exogenously added prostaglandins E1 and E2, but not F2alpha, inhibited the tumoricidal activity of interferon-activated macrophages of mice. A role for adenosine 3',5'-monophosphate (cyclic AMP) in modulating macrophage ...