Cancer of unknown primary (CUP) is a well-recognized clinical disorder where the primary site cannot be identified after a standard diagnostic approach and it accounts for 3-5 % of all tumors. CUP is distinguished into two ...

Currently, most of the neurodegenerative diseases lack effective therapeutic drugs. The present burden of these diseases on society highlights the need to develop novel approaches for their treatment. The detection of novel ...

General considerations Esophageal stenosis can be congenital or acquired Congenital esophageal stenosis is either related to abnormal differentiation during the development of the esophagus and the trachea or is due to ...

General considerations In this condition the patients need either hemodialysis or peritoneal dialysis to treat terminal renal insufficiency In our experience catheter longevity is superior after laparoscopic implantation ...

Triple-negative breast cancers comprise a heterogeneous group of tumors with varying prognosis, but the majority are of high histological grade and have a poor prognosis. Although there is considerable overlap between ...

This detailed, practical textbook focuses on immune mediated disorders of the nervous system with particular focus on systemic autoimmune disorders. Divided into three sections, the first discusses the neuroanatomical and ...

The term placebo refers to any intervention with no therapeutic effect that is used as a control in randomized controlled trials (RCTs). Placebo can produce a beneficial effect that cannot be attributed to the properties ...

21.1 General considerations Hypertrophy of the pyloric muscle causes gastric outlet obstruction Incidence 1:250 live births, most common in Caucasian populations 4:1 male-to-female ratio Family history often positive, ...