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Tamoxifen-induced severe hypertriglyceridemia and pancreatitis

dc.contributor.authorElisaf, Moses S.en
dc.contributor.authorNakou, K.en
dc.contributor.authorLiamis, G.en
dc.contributor.authorPavlidis, Nicholasen
dc.creatorElisaf, Moses S.en
dc.creatorNakou, K.en
dc.creatorLiamis, G.en
dc.creatorPavlidis, Nicholasen
dc.date.accessioned2018-06-22T09:52:59Z
dc.date.available2018-06-22T09:52:59Z
dc.date.issued2000
dc.identifier.urihttps://gnosis.library.ucy.ac.cy/handle/7/41602
dc.description.abstractTamoxifen exhibits favorable effects on the lipid and lipoprotein profile since it decreases the total and LDL cholesterol levels as well as the Lp(a) levels. Additionally, a small increase in serum triglycerides is commonly found after tamoxifen administration. However, severe hypertriglyceridemia which can sometimes be associated with life-threatening complications is occasionally noticed. Herein, we describe a patient who developed tamoxifen-induced severe hypertriglyceridemia and pancreatitis. An analysis of the underlying pathogenetic mechanisms as well as a review of the relevant literature is also provided.en
dc.language.isoengen
dc.sourceAnnals of Oncologyen
dc.subjectArticleen
dc.subjectAntineoplastic agentsen
dc.subjectCyclophosphamideen
dc.subjectFluorouracilen
dc.subjectHumanen
dc.subjectMethotrexateen
dc.subjectAdulten
dc.subjectBreast canceren
dc.subjectBreast neoplasmsen
dc.subjectFemaleen
dc.subjectPriority journalen
dc.subjectAbdominal painen
dc.subjectAntineoplastic combined chemotherapy protocolsen
dc.subjectCisplatinen
dc.subjectCase reporten
dc.subjectGemfibrozilen
dc.subjectTriacylglycerolen
dc.subjectAmylase blood levelen
dc.subjectDrug mechanismen
dc.subjectHormonalen
dc.subjectMiddle ageen
dc.subjectCholesterolen
dc.subjectCholesterol blood levelen
dc.subjectTamoxifenen
dc.subjectTriacylglycerol blood levelen
dc.subjectLipiden
dc.subjectLipoproteinen
dc.subjectAmylaseen
dc.subjectHypertriglyceridemiaen
dc.subjectPancreatitisen
dc.subjectPethidineen
dc.titleTamoxifen-induced severe hypertriglyceridemia and pancreatitisen
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1023/A:1008309613082
dc.description.volume11
dc.description.issue8
dc.description.startingpage1067
dc.description.endingpage1069
dc.author.facultyΙατρική Σχολή / Medical School
dc.author.departmentΙατρική Σχολή / Medical School
dc.type.uhtypeArticleen
dc.contributor.orcidPavlidis, Nicholas [0000-0002-2195-9961]
dc.contributor.orcidElisaf, Moses S. [0000-0003-0505-078X]
dc.gnosis.orcid0000-0002-2195-9961
dc.gnosis.orcid0000-0003-0505-078X


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