dc.contributor.author | Papaparaskeva, Georgia | en |
dc.contributor.author | Voutouri, Chrysovalantis | en |
dc.contributor.author | Gkretsi, Vasiliki | en |
dc.contributor.author | Achilleos, Mariliz | en |
dc.contributor.author | Safarik, Ivo | en |
dc.contributor.author | Pospiskova, Kristyna | en |
dc.contributor.author | Stylianopoulos, Triantafyllos | en |
dc.contributor.author | Krasia‐Christoforou, Theodora | en |
dc.creator | Papaparaskeva, Georgia | en |
dc.creator | Voutouri, Chrysovalantis | en |
dc.creator | Gkretsi, Vasiliki | en |
dc.creator | Achilleos, Mariliz | en |
dc.creator | Safarik, Ivo | en |
dc.creator | Pospiskova, Kristyna | en |
dc.creator | Stylianopoulos, Triantafyllos | en |
dc.creator | Krasia‐Christoforou, Theodora | en |
dc.date.accessioned | 2021-01-27T10:17:29Z | |
dc.date.available | 2021-01-27T10:17:29Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1439-2054 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/63697 | |
dc.description.abstract | Double-hydrophilic, semi-interpenetrating (semi-IPN) hydrogels are synthesized by encapsulating hydrophilic polyvinylpyrrolidone (PVP) linear chains in structure-defined 1,2-bis-(2-iodoethoxy)ethane (BIEE)-crosslinked (poly(2-(dimethylamino)ethyl methacrylate) (pDMAEMA) hydrogels. A series of semi-IPN double-hydrophilic hydrogels are prepared in which the pDMAEMA/BIEE content is kept the same and only the PVP content is varied, from 0 up to 33 wt%. The mechanical properties of the water-swollen hydrogels are experimentally evaluated under unconfined compressive loading conditions, while a nonlinear hyperelastic constitutive equation is used to predict their mechanical response. No significant difference is found in the mechanical response of the semi-IPN PVP/pDMAEMA/BIEE hydrogel containing 5 wt% PVP compared to the pDMAEMA/BIEE analog, however, for greater loading percentages (15 and 33 wt% of PVP), the semi-IPN hydrogels exhibit less stiffness/higher ductility. Furthermore, in vitro biocompatibility studies are carried out for the pDMAEMA/BIEE and the semi-IPN PVP/pDMAEMA/BIEE, indicating that both the formulations exhibit no toxicity in cultured cells. | en |
dc.language.iso | en | en |
dc.source | Macromolecular Materials and Engineering | en |
dc.source.uri | https://onlinelibrary.wiley.com/doi/abs/10.1002/mame.201700643 | |
dc.title | Tuning the Mechanical Properties of BIEE-Crosslinked Semi-Interpenetrating, Double-Hydrophilic Hydrogels | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1002/mame.201700643 | |
dc.description.volume | 303 | |
dc.description.issue | 6 | |
dc.author.faculty | Πολυτεχνική Σχολή / Faculty of Engineering | |
dc.author.department | Τμήμα Μηχανικών Μηχανολογίας και Κατασκευαστικής / Department of Mechanical and Manufacturing Engineering | |
dc.type.uhtype | Article | en |
dc.contributor.orcid | Stylianopoulos, Triantafyllos [0000-0002-3093-1696] | |
dc.contributor.orcid | Krasia‐Christoforou, Theodora [0000-0002-9915-491X] | |
dc.contributor.orcid | Voutouri, Chrysovalantis [0000-0003-3172-9489] | |
dc.contributor.orcid | Gkretsi, Vasiliki [0000-0002-3671-4078] | |
dc.gnosis.orcid | 0000-0002-3093-1696|0000-0002-9915-491X | |
dc.gnosis.orcid | 0000-0003-3172-9489 | |
dc.gnosis.orcid | 0000-0002-3671-4078 | |