• Article  

      Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells 

      Antoniades, Ioanna; Stylianou, Panayiota; Christodoulou, Neophytos; Skourides, Paris A. (2017)
      We previously identified focal adhesion kinase (FAK) as an important regulator of ciliogenesis in multiciliated cells. FAK and other focal adhesion (FA) proteins associate with the basal bodies and their striated rootlets ...
    • Article  

      Atomic Force Microscopy Probing of Cancer Cells and Tumor Microenvironment Components 

      Stylianou, A.; Stylianopoulos, T. (2016)
      Cancer cells have different characteristics from normal cells in terms of morphology, cell–cell interactions, cytoskeleton organization, cell growth rates, and cell-extracellular matrix interactions. Although the clarification ...
    • Article  

      Bandwidth and Directivity Enhancement of Loop Antenna by Nonperiodic Distribution of Mu-Negative Metamaterial Unit Cells 

      Rezaeieh, S. A.; Antoniades, Marcos A.; Abbosh, A. M. (2016)
      The theory, design, analysis, and verification of a wideband and unidirectional loop antenna loaded with mu-negative (MNG) metamaterial unit cells is presented. It is shown that by nonperiodic positioning of MNG unit cells ...
    • Conference Object  

      Breaking the walls: Scene partitioning and portal creation 

      Lerner, A.; Chrysanthou, Yiorgos L.; Cohen-Or, D. (IEEE Computer Society, 2003)
      In this paper, we revisit the cells-and-portals visibility methods, originally developed for the special case of architectural interiors. We define an effectiveness measure for a cells-and-portals partitioning, and introduce ...
    • Article  

      Comparing intracellular stability and targeting of sulfobetaine quantum dots with other surface chemistries in live cells 

      Muro, E.; Fragola, A.; Pons, T.; Lequeux, N.; Ioannou, Androulla; Skourides, Paris A.; Dubertret, B. (2012)
      The in vivo labeling of intracellular components with quantum dots (QDs) is very limited because of QD aggregation in the cell cytoplasm and/or QD confinement into lysosomal compartments. In order to improve intracellular ...
    • Article  

      Data-Driven Thread Execution on Heterogeneous Processors 

      Arandi, Samer; Matheou, George; Kyriacou, Costas; Evripidou, Paraskevas (2017)
      In this paper we report our experience in implementing and evaluating the Data-Driven Multithreading (DDM) model on a heterogeneous multi-core processor. DDM is a non-blocking multithreading model that decouples the ...
    • Conference Object  

      Detection of cell nuclei in breast biopsies using receptive fields 

      Schnorrenberg, F.; Pattichis, Constantinos S.; Kyriacou, Kyriacos C.; Schizas, Christos N. (IEEE, 1994)
      A biopsy analysis support system, called BASS, is introduced. The system uses an unsupervised object detection loop involving center-surround receptive fields, and a nonlinearity to mark the location of cell nuclei in an ...
    • Conference Object  

      The effects of applying cell-suppression and perturbation to aggregated genetic data 

      Antoniades, Athos; Keane, J.; Aristodimou, Aristos; Philipou, Christa; Constantinou, Andreas I.; Georgousopoulos, Christos; Tozzi, Federica; Kyriacou, Kyriacos C.; Hadjisavvas, Andreas; Loizidou, Maria A.; Demetriou, Christiana A.; Pattichis, Constantinos S. (2012)
      The key test for confidence in any association discovered within the medical domain is replication testing. That is, the ability of the association to be detected in independent populations. At the same time, in order to ...
    • Article  

      Efficient cells-and-portals partitioning 

      Lerner, A.; Chrysanthou, Yiorgos L.; Cohen-Or, D. (2006)
      In this paper we revisit the cells-and-portals visibility methods, originally developed for the special case of architectural interiors. We define an effectiveness measure for a cells-and-portals partition, and introduce ...
    • Article  

      Enhanced radio resource management algorithms for efficient MBMS service provision in UTRAN 

      Christophorou, C.; Pitsillides, Andreas; Lundborg, T. (2011)
      As currently specified by 3GPP, Multimedia Broadcast Multicast Service (MBMS) bearer services can be provided within a cell either by Point-to-Point (P-t-P) or Point-to-Multipoint (P-t-M) transmission mode, but not both ...
    • Conference Object  

      Enhanced UMTS simulation-based planning in office scenarios 

      Cabral, O.; Velez, F. J.; Hadjipollas, George; Stylianou, Marios; Antoniou, Josephina; Vassiliou, Vasos; Pitsillides, Andreas (Institute of Electrical and Electronics Engineers Inc., 2006)
      Enhanced UMTS traffic characterisation parameters have been addressed for the offices scenario. By using a system level simulator, results concerning QoS measures as packet delay, blocking and handover failure probabilities ...
    • Article  

      Gain Enhancement of Wideband Metamaterial-Loaded Loop Antenna with Tightly Coupled Arc-Shaped Directors 

      Ahdi Rezaeieh, S.; Antoniades, Marcos A.; Abbosh, A. M. (2017)
      A wideband and unidirectional loop antenna with enhanced and stable gain is presented. To reduce the size of the antenna, the loop is loaded with three mu-negative (MNG) metamaterial unit-cells. The proposed unit-cells ...
    • Article  

      Lopsided vortex cells in rotating Bose-Einstein condensates 

      Theodorakis, Stavros (2015)
      The amplitude |Ψ| of the wavefunction of a repulsive Bose-Einstein condensate in a two-dimensional axisymmetric harmonic trap decreases as we go from the center of the condensate towards its edge. Consequently the wavefunction ...
    • Conference Object  

      Mechanical stress regulates tissue oxygenation, cancer cell proliferation and drug delivery during progression of solid tumors 

      Mpekris, F.; Angeli, S.; Pirentis, A. P.; Stylianopoulos, T. (Springer Verlag, 2016)
      Oxygen supply plays a central role in cancer cell proliferation. While vascular density increases at the early stages of carcinogenesis, mechanical solid stresses developed during growth compress tumor blood vessels and, ...
    • Article  

      New antimony(III) halide complexes with dithiocarbamate ligands derived from thiuram degradation: The effect of the molecule's close contacts on in vitro cytotoxic activity 

      Urgut, O. S.; Ozturk, I. I.; Banti, Christina N.; Kourkoumelis, Nikolaos; Manoli, Maria; Tasiopoulos, Anastasios J.; Hadjikakou, Sotiris K. (2016)
      Antimony(III) halide complexes of the formulae {[SbBr(Me2DTC)2]n} (1), {[SbI(Me2DTC)2]n} (2) and {[(Me2DTC)2Sb(μ2-I)Sb(Me2DTC)2]+.I3-} (3) (Me2DTC = dimethyldithiocarbomate) were synthesized from SbX3, (X = Br or I) and ...
    • Conference Object  

      A new approach for efficient MBMS service provision in UTRAN 

      Christophorou, C.; Pitsillides, Andreas (2008)
      As currently specified by 3GPP, MBMS services can be provided in a cell either by Point-to-Point (PtP) or Point-to-Multipoint (PtM) transmission mode, but not both at the same time. With PtP transmission mode, one Dedicated ...
    • Conference Object  

      The performance vulnerability of architectural and non-architectural arrays to permanent faults 

      Hardy, D.; Sideris, I.; Ladas, N.; Sazeides, Yiannakis (2012)
      This paper presents a first-order analytical model for determining the performance degradation caused by permanently faulty cells in architectural and non-architectural arrays. We refer to this degradation as the performance ...
    • Conference Object  

      Portable parallel implementation of two novel mathematical biology algorithms in ZPL 

      Dikaiakos, Marios D.; Manoussaki, Daphne; Lin, Calvin; Woodward, Diana E. (ACM, 1995)
      This paper shows that mathematical models of biological pattern formation are ideally suited to data parallelism. We present two new algorithms, one for simulating the dynamic structure of fibroblasts, and the other for ...
    • Doctoral Thesis  Open Access

      The potential role of miR-548c-5p in regulating FOXC2 transcription in differentiating human podocytes 

      Christofides, Andrea T. (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2019-12)
      Τα ποδοκύτταρα είναι διαφοροποιημένα επιθηλιακά σπειραματικά κύτταρα και αποτελούν μέρος του φραγμού σπειραματικής διήθησης στο σπείραμα κάθε νεφρώνα. Ο πρώτος μοριακός δείκτης που εμφανίζεται στα ποδοκύτταρα είναι ο ...
    • Article  

      Solid Stress Facilitates Fibroblasts Activation to Promote Pancreatic Cancer Cell Migration 

      Kalli, M.; Papageorgis, P.; Gkretsi, V.; Stylianopoulos, T. (2018)
      Pancreatic fibroblasts are continuously gaining ground as an important component of tumor microenvironment that dynamically interact with cancer cells to promote tumor progression. In addition, these tumor-infiltrated ...