Browsing by Author "Kalogirou, Andreas S."
Now showing items 21-40 of 44
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Reaction of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine with benzyltriethylammonium chloride
Kalogirou, Andreas S.; Manoli, Maria; Koutentis, Panayiotis A. (2018)3,4,4,5-Tetrachloro-4H-1,2,6-thiadiazine was reacted with BnEt3NCl (10 mol%) to give perchloro-9-thia-1,5,8,10-tetraazaspiro[5.5]undeca-1,4,7,10-tetraene (up to 18% yield), 4,5,6-trichloropyrimidine-2-carbonitrile (up to ...
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The reaction of 4,5-dichloro-1,2,3-dithiazolium chloride with dimethylsulfonium dicyanomethylide: an improved synthesis of (4-chloro-1,2,3-dithiazolylidene)malononitrile
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2009)4,5-Dichloro-1,2,3-dithiazolium chloride 6 (Appel salt) reacts with dimethylsulfonium dicyanomethylide 11 to give 5-(4-chloro-1,2,3-dithiazolylidene)malononitrile 1 and a mixture of E/Z isomers of 3-(4-chloro-5H-1,2,3-di ...
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The reaction of 4,5-Dichloro-1,2,3-dithiazolium chloride with sulfimides: A new synthesis of N-Aryl-1,2,3-dithiazolimines
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2009)N-Aryl-S,S-dimethylsulfimides 3 (Ar = 4-NO2C6H4), 4 (Ar = Ph) and 5 (Ar = 4- Tol) react with Appel salt 1 to give the corresponding N-aryl-(4-chloro-5H-1, 2,3- dithiazolylidene)benzenamines 8 (Ar = 4-NO2C6H4), 9 (Ar = Ph) ...
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Reactions of Polychlorinated Pyrimidines with DABCO
Kalogirou, Andreas S.; Koutentis, Panayiotis A. (2019)The reaction of 2,4,5,6-tetrachloropyrimidine (4) and 4,5,6-trichloropyrimidine-2-carbonitrile (1) with DABCO (1 equiv.), in MeCN, at ca. 20 °
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Reactions of selected 3-bromoisothiazole-5-carbonitriles with the secondary dialkylamines pyrrolidine and morpholine
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2014)Readily available 3-bromoisothiazole-5-carbonitriles bearing various C-4 substituents [H, CO2R C[tbnd]N and halogen (Cl or Br)], react with either pyrrolidine or morpholine to give, in most cases, the 3-amino-substituted ...
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Regioselective geminal dichloride reactivity of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine: Access to 4,4-dioxo- and dithio-ketals
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2016)Treatment of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine (2) with selected alkanols, arenols and thiols led to regiospecific substitution of both geminal C-4 chlorines resulting in the formation of ketal or thioketal ...
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Ring transformation of (4-chloro-5H-1,2,3-dithiazol-5-ylidene)acetonitriles to 3-haloisothiazole-5-carbonitriles
Kalogirou, Andreas S.; Christoforou, Irene C.; Ioannidou, Heraklidia A.; Manos, Manolis J.; Koutentis, Panayiotis Andreas (2014)Ring transformation of readily prepared (4-chloro-5H-1,2,3-dithiazol-5- ylidene)acetonitriles afford 3-haloisothiazole-5-carbonitriles in good to excellent yields. The transformation can be mediated using HBr (g), HCl (g) ...
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Ring transformations of 2-hydroxy-(4-chloro-5H-1,2,3-dithiazol-5-ylideneamino)arenes
Kalogirou, Andreas S.; Michaelidou, Sophia S.; Koyioni, Maria G.; Koutentis, Panayiotis Andreas (2015)Abstract The cyclisation reactions of 2-(4-chloro-5H-1,2,3-dithiazol-5-ylidene-amino)phenol (5a), 3-(4-chloro-5H-1,2,3-dithiazol-5-ylideneamino)pyridin-2-ol (5b) and 2-(4-chloro-5H-1,2,3-dithiazol-5-ylideneamino)pyridin-3-ol ...
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RRegioselective geminal dichloride reactivity of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine: access to 4,4-dioxo- and dithio-ketals
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2016)
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Silver mediated direct C-H arylation of 3-bromoisothiazole-5-carbonitrile
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2014)Palladium catalyzed direct C-H arylation of 3-bromoisothiazole-5-carbonitrile with aryl/hetaryl iodides in the presence of AgF gave 13 4-aryl/hetaryl-3-bromoisothiazole-5-carbonitriles. The scope of this arylation was ...
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Spectroscopic characterization of C-4 substituted 3,5-dichloro-4H-1,2,6-thiadiazines
Theodorou, E.; Ioannidou, Heraklidia A.; Ioannou, Theodosia A.; Kalogirou, Andreas S.; Constantinides, Christos P.; Manoli, Maria; Koutentis, Panayiotis Andreas; Hayes, Sophia C. (2015)Three 3,5-dichloro-4H-1,2,6-thiadiazines, which differ according to the electron withdrawing nature of their substituent at C-4: (a) 3,5-dichloro-4-methylene-4H-1,2,6-thiadiazine (5a), (b) 3,5-dichloro-4H-1,2,6-thiadiazin-4-one ...
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Spectroscopic characterization of C-4 substituted 3,5-dichloro-4H-1,2,6-thiadiazines1
Theodorou, Eleni; Ioannidou, Heraklidia A.; Ioannou, Theodosia A.; Kalogirou, Andreas S.; Constantinides, Christos P.; Manoli, Maria; Koutentis, Panayiotis Andreas; Hayes, Sophia C. (2015)
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Structure‐Defined 3D Nanocomposite Polymer Networks: Versatile Heterogeneous Catalytic Platforms in Organic Synthesis
Kalogirou, Andreas S.; Achilleos, Mariliz; Procopiou, Constantina; Tanasǎ, Eugenia; Koutentis, Panayiotis Andreas; Krasia‐Christoforou, Theodora (2016)
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Substitution chemistry of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2016)The reactivity of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals towards nucleophilic substitution or palladium-catalyzed C–C coupling at the C-3/5 positions led to seven new 3,5-disubstituted 4H-1,2,6-thiadiazine ethylene ...
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Substitution chemistry of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals[ONLINE]
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2016)
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Symmetrical polymer systems prepared using a degradable bifunctional atom transfer radical polymerization initiator: Synthesis, characterization, and cleavage
Elladiou, Marios; Kalogirou, Andreas S.; Patrickios, Costas S. (2017)Linear (co)polymers and dimethacrylate-end-linked polymer networks of methyl methacrylate with 2-(dimethylamino)ethyl methacrylate, cleavable in the middle of the polymer chain, either under thermolysis or alkaline hydrolysis ...
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Synthesis and photophysical studies of a low-symmetry tribenzoisothiazoloporphyrazine
Molina, D.; El-Khouly, M. E.; Ioannou, Savvas; Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas; Sastre-Santos, A. (2016)A new low-symmetry tetraazaporphyrin has been synthesized and characterized by 1H NMR, electronic spectroscopies and high resolution mass spectrometry. The photophysical behavior of the newly synthesized low-symmetry zinc ...
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Synthesis and Reactivity of 3′,5′-Dichloro-1H-spiro(quinazoline-2,4′-[1,2,6]thiadiazin)-4(3H)-ones
Kalogirou, Andreas S.; Kourtellaris, Andreas; Koutentis, Panayiotis A. (2019)A three-step synthesis of 3?,5?-dichloro-1H-spiro(quinazo-line-2,4?-[1,2,6]thiadiazin)-4(3H)-ones starting from 3,4,4,5-tetra-chloro-4H-1,2,6-thiadiazine is presented. The latter reacts with 2-aminobenzonitriles to give ...
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Synthesis of 2-(4H-1,2,6-thiadiazin-4-ylidene)malononitriles
Kalogirou, Andreas S.; Koutentis, Panayiotis Andreas (2014)The base-free TiCl4-mediated condensation of 3,5-disubstituted-4H-1,2,6-thiadiazin-4-ones 8 with malononitrile affords 20 difficult to access (3,5-disubstituted-4H-1,2,6-thiadiazin-4-ylidene)malononitriles 7. The reaction ...
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Synthesis of 2-Cyanopyrimidines
Kalogirou, Andreas S.; Koutentis, Panayiotis A. (2019)4,6-Dichloro-2-(methylthio)pyrimidine (7) was converted to 4-chloro-6-methoxy-2-(methylthio)pyrimidine (15) and 4,6-dimethoxy-2-(methylthio)pyrimidine (14). Chlorination of the latter with N-chlorosuccinimide (NCS) affords ...