Browsing by Author "Pentheroudakis, George"
Now showing items 21-40 of 104
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Cavitating squamous cell lung carcinoma-distinct entity or not? Analysis of radiologic, histologic, and clinical features
Pentheroudakis, George; Kostadima, Lida; Fountzilas, George; Kalogera-Fountzila, Anna; Klouvas, G. D.; Kalofonos, H. P.; Pavlidis, Nicholas (2004)Introduction: Patients with cavitating squamous lung carcinoma (cSLC) are believed to harbor aggressive, chemoresistant disease with distinct features and fare poorly. We retrospectively analyzed radiologic, histologic, ...
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Cervical lymph node metastases of squamous cell carcinoma from an unknown primary site: A favourable prognosis subset of patients with CUP
Pavlidis, Nicholas; Pentheroudakis, George; Plataniotis, G. (2009)Squamous cervical cancer of unknown primary site (SQCCUP) presents in patients as neck lymph nodes involved by squamous carcinoma in the absence of identifiable primary in the head, neck or lung. This CUP subset affects ...
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Chemotherapy for patients with two favourable subsets of unknown primary carcinoma: Active, but how effective?
Pentheroudakis, George; Briassoulis, E. Ch; Karavasilis, V.; Fountzilas, George; Xeros, N.; Samelis, G.; Samantas, E.; Pavlidis, Nicholas (2005)Carcinoma of unknown primary (CUP) is characterized by dismal patient survival. The outcome of patients with two favourable risk CUP subsets was studied. Eighty patients diagnosed with either midline lymph node metastases ...
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Colorectal cancer screening awareness in European primary care
Mauri, D.; Pentheroudakis, George; Milousis, A.; Xilomenos, A.; Panagoulopoulou, E.; Bristianou, M.; Zacharias, G.; Christidis, D.; Mustou, E. A.; Gkinosati, A.; Pavlidis, Nicholas (2006)Background: Adjustment for stage at diagnosis markedly reduces USA versus European colorectal cancer survival differences and a screening bias was therefore suspected. Moreover, little is known about colorectal cancer ...
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Comparative survival with diverse chemotherapy regimens for cancer of unknown primary site: Multiple-treatments meta-analysis
Golfinopoulos, Vassilis; Pentheroudakis, George; Salanti, G.; Nearchou, A. D.; Ioannidis, J. P. A.; Pavlidis, Nicholas (2009)Objectives: To synthesize the evidence from randomized controlled trials concerning systemic treatment regimens for patients with cancer of unknown primary site (CUP). Data sources: PubMed and the Cochrane Library Central ...
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Development of a low grade lymphoma in the mastoid bone in a patient with atypical Cogan's syndrome: A case report
Kalogeropoulos, C.; Karachalios, D.; Pentheroudakis, George; Tsikou-Papafrangou, A.; Abou-Asabeh, L.; Argyropoulou, Maria I.; Drosos, Alexandros A.; Pavlidis, Nicholas (2015)Cogan's syndrome is a rare disorder characterized by ocular and audiovestibular manifestations in its typical form and caries a wide variety of atypical manifestations. It is considered as an autoimmune disease. We present ...
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Disseminated intravascular coagulation (DIC) and non-small cell lung cancer (NSCLC): Report of a case and review of the literature
Voulgaris, E.; Pentheroudakis, George; Vassou, A.; Pavlidis, Nicholas (2009)The clinical manifestation of disseminated intravascular coagulation (DIC) as paraneoplastic phenomenon is common in patients with lung cancer (especially in those with non small cell lung cancer).Surprisingly, only few ...
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Docetaxel and carboplatin combination chemotherapy as outpatient palliative therapy in carcinoma of unknown primary: A multicentre Hellenic Cooperative Oncology Group phase II study
Pentheroudakis, George; Briassoulis, E. Ch; Kalofonos, H. P.; Fountzilas, George; Economopoulos, T.; Samelis, G.; Koutras, A. K.; Karina, M.; Xiros, N.; Samantas, E.; Bamias, A. T.; Pavlidis, Nicholas (2008)Introduction. Taxane/platinum combinations exhibit synergistic cytotoxicity and activity against a broad range of solid tumours. We sought to optimise the regimen as a suitable outpatient palliative treatment for cancer ...
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Docetaxel-induced enterocolitis: A serious and potentially fatal adverse event
Boussios, Stergios; Pentheroudakis, George; Kamina, S.; Katsanos, K.; Pavlidis, Nicholas (2011)
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Donor-derived breast cancer in a bone marrow transplantation recipient
Golfinopoulos, Vassilis; Pentheroudakis, George; Kamakari, S.; Metaxa-Mariatou, V.; Pavlidis, Nicholas (2009)We present the case of a young lady who had been treated for acute myelocytic leukemia at the age of 14 by means of allogeneic bone marrow transplantation, the donor being her sister. At the age of 28 she underwent modified ...
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Donor-derived breast cancer in a bone marrow transplantation recipient (Breast Cancer Research and Treatment DOI: 10.1007/s10549-008-9922-7
Golfinopoulos, Vassilis; Pentheroudakis, George; Kamakari, S.; Metaxa-Mariatou, V.; Pavlidis, Nicholas (2009)
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Elderly patients with squamous lung carcinoma: Faring better or worse?
Pentheroudakis, George; Neanidis, K.; Kostadima, Lida; Fountzilas, George; Pavlidis, Nicholas (2006)Introduction: Nonsmall cell lung cancer is increasingly diagnosed at an advanced age and squamous cell carcinoma is the commonest histological type encountered in older patients. The clinical course, management, and outcome ...
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ESMO consensus conferences: Another source of ESMO clinical practice guidelines
Pavlidis, Nicholas; Stahel, R. A.; Pentheroudakis, George; Cervantes, A. (2012)
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The ESMO guideline strategy: An identity statement and reflections on improvement
Pentheroudakis, George; Cardoso, Fatima; Arnold, D.; Sessa, Cristiana; Peters, S.; Horwich, A.; Pavlidis, Nicholas; Stahel, R. A.; Cervantes, A. (2015)Guidelines should provide recommendations on the optimal management of a patient in specific clinical circumstances based on the scientific evidence. ESMO, as Europe's leading society in medical oncology produces a range ...
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Exploring the biology of cancer of unknown primary: Breakthroughs and drawbacks
Kamposioras, K.; Pentheroudakis, George; Pavlidis, Nicholas (2013)Background: Cancer of unknown primary (CUP) ranks among the ten most common malignancies worldwide. Cancer of unknown primary presents as disseminated disease, has a dismal prognosis and remains a diagnosis of exclusion. ...
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Gastrointestinal, urologic and lung malignancies during pregnancy.
Pentheroudakis, George; Pavlidis, Nicholas (2008)
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Gene expression of estrogen receptor, progesterone receptor and microtubule-associated protein Tau in high-risk early breast cancer: A quest for molecular predictors of treatment benefit in the context of a Hellenic Cooperative Oncology Group trial
Pentheroudakis, George; Kalogeras, K. T.; Wirtz, R. M.; Grimani, I.; Zografos, G.; Gogas, H.; Stropp, U.; Pectasides, Dimitrios; Skarlos, Dimosthenis V.; Hennig, G.; Samantas, E.; Bafaloukos, Dimitrios; Papakostas, P.; Kalofonos, H. P.; Pavlidis, Nicholas; Fountzilas, George (2009)Background Estrogen receptor (ER) and progesterone receptor (PgR) protein expression carry weak prognostic and moderate predictive utility for the outcome of early breast cancer patients on adjuvant chemohormonotherapy. ...
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Global microRNA profiling in favorable prognosis subgroups of cancer of unknown primary (CUP) demonstrates no significant expression differences with metastases of matched known primary tumors
Pentheroudakis, George; Spector, Y.; Krikelis, D.; Kotoula, V.; Meiri, E.; Malamou-Mitsi, Vassiliki D.; Fountzilas, George; Sanden, M.; Pavlidis, Nicholas; Benjamin, H.; Aharonov, R. (2013)No data exist on biologic differences between Cancer of unknown primary (CUP) and metastatic solid tumors of known primary site. We assigned a primary tissue of origin in 40 favorable CUP patients (A: serous peritoneal ...
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Global profiling of EGFR gene mutation, amplification, regulation and tissue protein expression in unknown primary carcinomas: To target or not to target?
Dova, L.; Pentheroudakis, George; Georgiou, I.; Malamou-Mitsi, Vassiliki D.; Vartholomatos, G.; Fountzilas, George; Kolaitis, N.; Kitsou, E.; Pavlidis, Nicholas (2007)Introduction: Epidermal growth factor receptor (EGFR) signalling contributes to malignant transformation and survival. We studied molecular predictors of benefit from EGFR-modulating therapies in patients with cancer of ...
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Heterogeneity in cancer guidelines: Should we eradicate or tolerate?
Pentheroudakis, George; Stahel, R. A.; Hansen, H.; Pavlidis, Nicholas (2008)Background: Heterogeneity in aspects of development, structure and context of oncology guidelines was not evaluated. We analysed and critically examined its implications. Materials and methods: Nine cancer clinical practice ...