• Article  

      Abnormal functional activation and maturation of fronto-striato-temporal and cerebellar regions during sustained attention in autism spectrum disorder 

      Christakou, A.; Giampietro, V.; Brammer, Michael; Smith, A. B.; Robertson, D. M.; Rubia, K.; Bailey, Anthony J.; Baron-Cohen, Simon; Bolton, P. F.; Bullmore, Edward T.; Carrington, S.; Chakrabarti, B.; Daly, Eileen M.; Deoni, Sean C. L.; Ecker, C.; Happé, Francesca; Henty, Julian; Jezzard, Peter; Johnston, Patrick; Jones, D. K.; Lombardo, Michael V.; Madden, A.; Mullins, D.; Murphy, Declan G. M.; Pasco, Greg; Sadek, Susan A.; Spain, D.; Steward, R.; Suckling, John; Wheelwright, Sally J.; Williams, Steven C. R. (2014)
      Objective: Sustained attention problems are common in people with autism spectrum disorder (ASD) and may have significant implications for the diagnosis and management of ASD and associated comorbidities. Furthermore, ASD ...
    • Article  

      Are power calculations useful? A multicentre neuroimaging study 

      Suckling, John; Henty, Julian; Ecker, C.; Deoni, Sean C. L.; Lombardo, Michael V.; Baron-Cohen, Simon; Jezzard, Peter; Barnes, Anna; Chakrabarti, B.; Ooi, Cinly; Lai, Meng-Chuan; Williams, Steven C. R.; Murphy, Declan G. M.; Bullmore, Edward T. (2014)
      There are now many reports of imaging experiments with small cohorts of typical participants that precede large-scale, often multicentre studies of psychiatric and neurological disorders. Data from these calibration ...
    • Article  

      Association between the probability of autism spectrum disorder and normative sex-related phenotypic diversity in brain structure 

      Ecker, C.; Andrews, Derek Sayre; Gudbrandsen, Christina M.; Marquand, Andre F.; Ginestet, Cedric E.; Daly, Eileen M.; Murphy, Clodagh M.; Lai, Meng-Chuan; Lombardo, Michael V.; Ruigrok, Amber N. V.; Bullmore, Edward T.; Suckling, John; Williams, Steven C. R.; Baron-Cohen, Simon; Craig, Michael C.; Murphy, Declan G. M. (2017)
      IMPORTANCE Autism spectrum disorder (ASD) is 2 to 5 times more common in male individuals than in female individuals. While the male preponderant prevalence of ASD might partially be explained by sex differences in clinical ...
    • Article  

      Decreased centrality of cortical volume covariance networks in autism spectrum disorders 

      Balardin, J. B.; Comfort, W. E.; Daly, Eileen M.; Murphy, Clodagh M.; Andrews, Derek Sayre; Murphy, Declan G. M.; Ecker, C.; Sato, J. R.; Bailey, Anthony J.; Baron-Cohen, Simon; Bolton, P. F.; Bullmore, Edward T.; Carrington, S.; Catani, Marco; Chakrabarti, B.; Craig, Michael C.; Daly, Eileen M.; Deoni, Sean C. L.; Happé, Francesca; Henty, Julian; Jezzard, Peter; Johnston, Patrick; Jones, D. K.; Lai, Meng-Chuan; Lombardo, Michael V.; Madden, A.; Mullins, D.; Murphy, Clodagh M.; Murphy, Declan G. M.; Pasco, Greg; Ruigrok, Amber N. V.; Sadek, Susan A.; Spain, D.; Stewart, R.; Suckling, John; Wheelwright, Sally J.; Williams, Steven C. R.; Wilson, C. E.; MRC AIMS Consortium (2015)
      Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by atypical structural and functional brain connectivity. Complex network analysis has been mainly used to describe altered ...
    • Article  

      In Vivo Evidence of Reduced Integrity of the Gray-White Matter Boundary in Autism Spectrum Disorder 

      Andrews, Derek Sayre; Avino, Thomas A.; Gudbrandsen, Maria; Daly, Eileen M.; Marquand, Andre F.; Murphy, Clodagh M.; Lai, Meng-Chuan; Lombardo, Michael V.; Ruigrok, Amber N. V.; Williams, Steven C. R.; Bullmore, Edward T.; Suckling, John; Baron-Cohen, Simon; Craig, Michael C.; Murphy, Declan G. M.; Ecker, Christine (2017)
      Atypical cortical organization and reduced integrity of the gray-white matter boundary have been reported by postmortem studies in individuals with autism spectrum disorder (ASD). However, there are no in vivo studies that ...
    • Article  

      Neural self-representation in autistic women and association with ‘compensatory camouflaging’: 

      Lai, Meng-Chuan; Lombardo, Michael V.; Chakrabarti, Bhismadev; Ruigrok, Amber NV; Bullmore, Edward T.; Suckling, John; Auyeung, Bonnie; Happé, Francesca; Szatmari, Peter; Baron-Cohen, Simon (2019)
      Prior work has revealed sex/gender-dependent autistic characteristics across behavioural and neural/biological domains. It remains unclear whether and how neura...
    • Article  

      Organizational effects of fetal testosterone on human corpus callosum size and asymmetry 

      Chura, Lindsay R.; Lombardo, Michael V.; Ashwin, Emma; Auyeung, Bonnie; Chakrabarti, B.; Bullmore, Edward T.; Baron-Cohen, Simon (2010)
      Previous theory and research in animals has identified the critical role that fetal testosterone (FT) plays in organizing sexually dimorphic brain development. However, to date there are no studies in humans directly testing ...
    • Article  

      Sex-specific impact of prenatal androgens on social brain default mode subsystems 

      Lombardo, Michael V.; Auyeung, Bonnie; Pramparo, Tiziano; Courraud, Jérémie; Holt, Rosemary J.; Waldman, Jack; Ruigrok, Amber N. V.; Mooney, Natasha; Bethlehem, Richard A. I.; Lai, Meng-Chuan; Kundu, Prantik; Bullmore, Edward T.; Mandel, Jean-Louis; Piton, Amélie; Baron-Cohen, Simon; Quartier, Angélique (2018)
      Early-onset neurodevelopmental conditions (e.g., autism) affect males more frequently than females. Androgens may play a role in this male-bias by sex-differentially impacting early prenatal brain development, particularly ...
    • Article  

      Shared neural circuits for mentalizing about the self and others 

      Lombardo, Michael V.; Chakrabarti, B.; Bullmore, Edward T.; Wheelwright, Sally J.; Sadek, Susan A.; Suckling, John; Baron-Cohen, Simon; Bailey, Anthony J.; Bolton, P. F.; Carrington, S.; Daly, Eileen M.; Deoni, Sean C. L.; Ecker, C.; Happé, Francesca; Henty, Julian; Jezzard, Peter; Johnston, Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy, Clodagh M.; Murphy, Declan G. M.; Pasco, Greg; Spain, D.; Stewart, R.; Williams, Steven C. R. (2010)
      Although many examples exist for shared neural representations of self and other, it is unknown how such shared representations interact with the rest of the brain. Furthermore, do high-level inference-based shared mentalizing ...