Browsing by Author "Christaki, Eirini"
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Assessing Depression in Male and Female Medical Students
Triantafyllou, G.; Triantafyllou, A.; Gavriilaki, E.; Anyfanti, Panagiota; Avagianou, P.-A.; Christaki, Eirini; Lazaridis, Nikolaos; Petidis, K.; Panagos, C.; Nikolaidou, B.; Sachpekidis, C.; Gkioultzis, T.; Doumas, M. (2011)
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Association of Sexual Dysfunction with Global Health-Related Quality of Life in Female Patients with Rheumatic Diseases
Anyfanti, Panagiota; Triantafyllou, A.; Triantafyllou, G.; Gavriilaki, E.; Pyrpasopoulou, A.; Chatzimichailidou, S.; Christaki, Eirini; Glystra, A.; Doumas, Stergios; Aslanidis, S.; Doumas, M. (2011)
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The beginning of personalized medicine in sepsis: Small steps to a bright future
Christaki, Eirini; Giamarellos-Bourboulis, Evangelos J. (2014)There is a growing recognition that there is a need for a more personalized approach towards sepsis care. In most clinical trials investigating novel therapeutic interventions against sepsis, patients have been considered ...
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The complex pathogenesis of bacteremia: From antimicrobial clearance mechanisms to the genetic background of the host
Christaki, Eirini; Giamarellos-Bourboulis, Evangelos J. (2014)Bacteremia develops when bacteria manage to escape the host immune mechanisms or when the otherwise well-orchestrated immune response fails to control bacterial spread due to inherent or acquired immune defects that are ...
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Estimating Prevalence and Predictors of Sexual Dysfunction among Female Medical Students
Triantafyllou, G.; Triantafyllou, A.; Gavriilaki, E.; Anyfanti, Panagiota; Petidis, K.; Gkaliagkousi, E.; Papadopoulos, N.; Christaki, Eirini; Lazaridis, Nikolaos; Nikolaidou, B.; Doumas, M. (2011)
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Estrogen receptor β agonism increases survival in experimentally induced sepsis and ameliorates the genomic sepsis signature: A pharmacogenomic study
Christaki, Eirini; Opal, Steven M.; Jr, James C. Keith; Kessimian, Nubar; Palardy, J. E.; Parejo, N. A.; LaVallie, Edward R.; Racie, L.; Mounts, W.; Malamas, Michael S.; Mewshaw, Richard E.; Harris, Heather A.; Vlasuk, G. P. (2010)Background. Nonsteroidal agonists have been developed that selectively bind to and activate estrogen receptor β (ERβ) rather than estrogen receptor α (ERα). ERβ is expressed equally in both male and female mammals in ...
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Gender Effects on Anxiety Levels in Men with Rheumatic Disorders
Gavriilaki, E.; Triantafyllou, A.; Anyfanti, Panagiota; Avagianou, P.-A.; Triantafyllou, G.; Pyrpasopoulou, A.; Chatzimichailidou, S.; Gkaliagkousi, E.; Petidis, K.; Christaki, Eirini; Doumas, Stergios; Aslanidis, S.; Doumas, M. (2011)
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Hair cortisol concentrations exhibit a positive association with salivary cortisol profiles and are increased in obese prepubertal girls
Papafotiou, C.; Christaki, Eirini; Akker, E. L. T. van den; Wester, V. L.; Apostolakou, Filia; Papassotiriou, Y.; Chrousos, George P.; Pervanidou, P. (2017)Cortisol, a key mediator of the stress response, has been associated with obesity and metabolic syndrome manifestations as early as in childhood. Scalp hair cortisol has been proposed as a reliable index of long-term ...
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Host immune response in sepsis due to ventilator-associated pneumonia: How is it different?
Christaki, Eirini (2009)Current evidence regarding potentially different host response mechanisms in sepsis according to the type of initiating infection is sporadic. It is possible that alterations in cell populations, variations in effector ...
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Immunomodulatory therapy for sepsis: An update
Christaki, Eirini; Anyfanti, Panagiota; Opal, Steven M. (2011)Currently the treatment mainstay of sepsis is early and appropriate antibiotic therapy, accompanied by aggressive fluid administration, the use of vasopressors when needed and the prompt initiation of measures to support ...
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The Impact of Sexual Dysfunction on Quality of Life in Male and Female Patients with Musculoskeletal Disorders
Triantafyllou, A.; Gavriilaki, E.; Triantafyllou, G.; Anyfanti, Panagiota; Pyrpasopoulou, A.; Petidis, K.; Chatzimichailidou, S.; Gkaliagkousi, E.; Nikolaidou, B.; Christaki, Eirini; Doumas, Stergios; Aslanidis, S.; Doumas, M. (2011)
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Influenza Virus—Host Co-evolution. A Predator-Prey Relationship?
Voskarides, Konstantinos; Christaki, Eirini; Nikolopoulos, Georgios K. (2018)Influenza virus continues to cause yearly seasonal epidemics worldwide and periodically pandemics. Although influenza virus infection and its epidemiology have been extensively studied, a new pandemic is likely. One of the ...
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Is the mortality rate for septic shock really decreasing?
Christaki, Eirini; Opal, Steven M. (2008)Survival rates for patients in septic shock have gradually improved in critical care units worldwide over the last 25 years. Further improvement will be predicated on the discovery of new therapies to disrupt the underlying ...
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The kinetics of T regulatory cells in shock: Beyond sepsis
Christaki, Eirini; Patrozou, E. (2010)During the past decade, there have been an increasing number of studies investigating the precise role of T regulatory cells in human disease. First recognized for their ability to prevent autoimmunity, T regulatory cells ...
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Microbiology of acute bacterial skin and skin-structure infections in Greece: A proposed clinical prediction score for the causative pathogen
Christaki, Eirini (2019)Although clinical definitions of acute bacterial skin and skin-structure infection (ABSSSI) are now well established, guidance of the prediction of likely pathogens based on evidence is missing. This was a large survey of ...
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A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia
Christaki, Eirini; Opal, Steven M.; Jr, James C. Keith; Kessimian, Nubar; Palardy, J. E.; Parejo, N. A.; Tan, X. Y.; Piche-Nicholas, N.; Tchistiakova, L.; Vlasuk, G. P.; Shields, K. M.; Feldman, Jeffrey L.; LaVallie, Edward R.; Arai, Maya; Mounts, W.; Pittman, D. D. (2011)The RAGE (receptor for advanced glycation end products) is believed to play a role in sepsis by perpetuating inflammation. The interaction of RAGE with a variety of host-derived ligands that accumulate during stress and ...
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New technologies in predicting, preventing and controlling emerging infectious diseases
Christaki, Eirini (2015)Surveillance of emerging infectious diseases is vital for the early identification of public health threats. Emergence of novel infections is linked to human factors such as population density, travel and trade and ecological ...
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NK and NKT cell depletion alters the outcome of experimental pneumococcal pneumonia: Relationship with regulation of interferon- γ production
Christaki, Eirini; Diza, Evdoxia; Giamarellos-Bourboulis, Evangelos J.; Papadopoulou, Nikoletta; Pistiki, Aikaterini; Droggiti, Dionysia-Irini; Georgitsi, Marianna; Machova, Alzbeta; Lambrelli, Dimitra; Malisiovas, Nicolaos; Nikolaidis, Pavlos; Opal, Steven M. (2014)Background. Natural killer (NK) and natural killer T (NKT) cells contribute to the innate host defense but their role in bacterial sepsis remains controversial. Methods. C57BL/6 mice were infected intratracheally with 5 × ...
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NK and NKT Cell Depletion Alters the Outcome of Experimental Pneumococcal Pneumonia: Relationship with Regulation of Interferon-gamma Production
Christaki, Eirini; Diza, Evdoxia; Giamarellos-Bourboulis, Evangelos J.; Papadopoulou, Nikoletta; Pistiki, Aikaterini; Droggiti, Dionysia-Irini; Georgitsi, Marianna; Machova, Alzbeta; Lambrelli, Dimitra; Malisiovas, Nicolaos; Nikolaidis, Pavlos; Opal, Steven M. (2015)Background. Natural killer (NK) and natural killer T (NKT) cells contribute to the innate host defense but their role in bacterial sepsis remains controversial. Methods. C57BL/6 mice were infected intratracheally with 5 x ...
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Personalized medicine in sepsis: The coming of age
Christaki, Eirini (2013)"a there is both the need to discover specific and clinically useful biomarkers in order to diagnose sepsis, define the hosta s immune status, monitor treatment and define prognosis and to develop medications that would ...