Browsing by Author "Dardiotis, Efthimios"

Now showing items 1-17 of 17

    • Article  

      Apolipoprotein ε4 allele is associated with frailty syndrome: results from the hellenic longitudinal investigation of ageing and diet study 

      Mourtzi, Niki; Ntanasi, Eva; Yannakoulia, Mary; Kosmidis, Mary; Anastasiou, Costas; Dardiotis, Efthimios; Hadjigeorgiou, Giorgos; Sakka, Paraskevi; Scarmeas, Nikolaos (2019)
      Apolipoprotein (APOE) ε4 allele has been associated with a number of age-related diseases but previous studies failed to identify any link with Frailty syndrome. The aim of the present study is to investigate the association ...
    • Article  

      AQP4 tag SNPs in patients with intracerebral hemorrhage in Greek and Polish population 

      Dardiotis, Efthimios; Siokas, Vasileios; Marogianni, Chrysa; Aloizou, Athina-Maria; Sokratous, Maria; Paterakis, Konstantinos; Dardioti, Maria; Grigoriadis, Savas; Brotis, Alexandros; Kapsalaki, Eftychia; Fountas, Kostas; Jagiella, Jeremiasz; Hadjigeorgiou, Georgios M. (2019)
      BACKROUND: A relatively small number of genetic variants are implicated to pathophysiology of intracerebral hemorrhage (ICH). Aquaporin-4 (AQP4) has been reported to be implicated in the pathophysiological processes of ICH ...
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      Associations between the mediterranean diet and sleep in older adults: Results from the hellenic longitudinal investigation of aging and diet study 

      Mamalaki, Eirini; Anastasiou, Costas A.; Ntanasi, Eva; Tsapanou, Angeliki; Kosmidis, Mary H.; Dardiotis, Efthimios; Hadjigeorgiou, Giorgos M.; Sakka, Paraskevi; Scarmeas, Nikolaos; Yannakoulia, Mary (2018)
      18: 1543-1548.
    • Article  

      Associations between the Mediterranean diet and sleep in the elderly 

      Mamalaki, Eirini; Anastasiou, Costas; Kosmidis, Mary; Dardiotis, Efthimios; Hadjigeorgiou, Giorgos; Sakka, Paraskevi; Scarmeas, Nikolaos; Yannakoulia, Mary (2018)
    • Article  

      BDNF rs6265 (Val66Met) Polymorphism as a Risk Factor for Blepharospasm 

      Siokas, Vasileios; Kardaras, Dimitrios; Aloizou, Athina-Maria; Asproudis, Ioannis; Boboridis, Konstadinos G.; Papageorgiou, Eleni; Hadjigeorgiou, Georgios M.; Tsironi, Evangelia E.; Dardiotis, Efthimios (2019)
      A few genetic variants are implicated in the development of blepharospasm (BSP). The precise role of the rs6265 on the brain-derived neurotrophic factor (BDNF) gene on BSP remains controversial. The effect of rs6265 on BSP ...
    • Article  

      CpG Island Methylation Patterns in Relapsing-Remitting Multiple Sclerosis 

      Sokratous, Maria; Dardiotis, Efthimios; Bellou, Eleni; Tsouris, Zisis; Michalopoulou, Amalia; Dardioti, Maria; Siokas, Vasileios; Rikos, Dimitrios; Tsatsakis, Aristidis; Kovatsi, Leda; Bogdanos, Dimitrios P.; Hadjigeorgiou, Georgios M. (2018)
      DNA methylation may predispose to multiple sclerosis (MS), as aberrant methylation in the promoter regions across the genome seems to underlie several processes of MS. We have currently determined the methylation status ...
    • Article  

      Dementia Prevalence in Greece: The Hellenic Longitudinal Investigation of Aging and Diet (HELIAD) 

      Kosmidis, Mary H.; Vlachos, George S.; Anastasiou, Costas A.; Yannakoulia, Mary; Dardiotis, Efthimios; Hadjigeorgiou, Georgios; Sakka, Paraskevi; Ntanasi, Eva; Scarmeas, Nikolaos (2018)
      INTRODUCTION: Study of the epidemiology of dementia to gain insight into putative predisposing and prophylactic factors is the first step toward establishing effective preventive and therapeutic strategies for this ...
    • Article  

      Differential effects of completed and incomplete pregnancies on the risk of Alzheimer disease 

      Jang, Hyesue; Bae, Jong Bin; Dardiotis, Efthimios; Scarmeas, Nikolaos; Sachdev, Perminder S.; Lipnicki, Darren M.; Han, Ji Won; Kim, Tae Hui; Kwak, Kyung Phil; Kim, Bong Jo; Kim, Shin Gyeom; Kim, Jeong Lan; Moon, Seok Woo; Park, Joon Hyuk; Ryu, Seung-Ho; Youn, Jong Chul; Lee, Dong Young; Lee, Dong Woo; Lee, Seok Bum; Lee, Jung Jae; Jhoo, Jin Hyeong; Yannakoulia, Mary; Kosmidis, Mary H.; Hadjigeorgiou, Giorgos M.; Sakka, Paraskevi; Kim, Ki Woong (2018)
      OBJECTIVE: To investigate the effects of completed pregnancy with childbirth and incomplete pregnancy without childbirth on the late-life cognition and the risk of Alzheimer disease (AD) in women. METHODS: Using the pooled ...
    • Article  

      Genetic polymorphisms in amyotrophic lateral sclerosis: Evidence for implication in detoxification pathways of environmental toxicants 

      Dardiotis, Efthimios; Siokas, Vasileios; Sokratous, Maria; Tsouris, Zisis; Michalopoulou, Amalia; Andravizou, Athina; Dastamani, Metaxia; Ralli, Styliani; Vinceti, Marco; Tsatsakis, Aristidis; Hadjigeorgiou, Georgios M. (2018)
    • Article  

      Higher probability of prodromal Parkinson disease is related to lower cognitive performance 

      Bougea, Anastasia; Maraki, Maria I.; Yannakoulia, Mary; Stamelou, Maria; Xiromerisiou, Georgia; Kosmidis, Mary H.; Ntanasi, Eva; Dardiotis, Efthimios; Hadjigeorgiou, Georgios M.; Sakka, Paraskevi; Anastasiou, Costas A.; Stefanis, Leonidas; Scarmeas, Nikolaos (2019)
      Objective Given the limited information on cognitive function before Parkinson disease (PD) clinical onset in the general population, we sought to assess prodromal PD (pPD) probability and relate it to detailed ...
    • Article  

      Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease 

      Maraki, Maria I.; Yannakoulia, Mary; Stamelou, Maria; Stefanis, Leonidas; Xiromerisiou, Georgia; Kosmidis, Mary H.; Dardiotis, Efthimios; Hadjigeorgiou, Georgios M.; Sakka, Paraskevi; Anastasiou, Costas A.; Simopoulou, Eleni; Scarmeas, Nikolaos (2019)
      Background The International Parkinson and Movement Disorder Society recently introduced a methodology for probability score calculation for prodromal PD. Objectives To assess the probability of prodromal PD in an older ...
    • Article  

      Mediterranean Lifestyle in Relation to Cognitive Health: Results from the HELIAD Study 

      Anastasiou, Costas A.; Yannakoulia, Mary; Kontogianni, Meropi D.; Kosmidis, Mary H.; Mamalaki, Eirini; Dardiotis, Efthimios; Hadjigeorgiou, Giorgos; Sakka, Paraskevi; Tsapanou, Angeliki; Lykou, Anastasia; Scarmeas, Nikolaos (2018)
      Many lifestyle factors have been linked to cognitive function but little is known about their combined effect. An overall lifestyle pattern for people living in the Mediterranean basin has been proposed, including diet, ...
    • Article  

      Precision Medicine and Global Health: The Good, the Bad, and the Ugly 

      Mentis, Alexios-Fotios A.; Pantelidi, Kleoniki; Dardiotis, Efthimios; Hadjigeorgiou, Georgios M.; Petinaki, Efthimia (2018)
    • Article  

      Replication study of GWAS risk loci in Greek multiple sclerosis patients 

      Hadjigeorgiou, Georgios M.; Kountra, Persia-Maria; Koutsis, Georgios; Tsimourtou, Vana; Siokas, Vasileios; Dardioti, Maria; Rikos, Dimitrios; Marogianni, Chrysoula; Aloizou, Athina-Maria; Karadima, Georgia; Ralli, Styliani; Grigoriadis, Nikolaos; Bogdanos, Dimitrios; Panas, Marios; Dardiotis, Efthimios (2019)
      To validate in an ethnically homogeneous Greek multiple sclerosis (MS) cohort, genetic risk factors for the disease, identified through a number of previous multi-ethnic genome-wide association studies (GWAS).
    • Article  

      Sleep and subjective cognitive decline in cognitively healthy elderly: Results from two cohorts 

      Tsapanou, Angeliki; Vlachos, Georgios S.; Cosentino, Stephanie; Gu, Yian; Manly, Jennifer J.; Brickman, Adam M.; Schupf, Nicole; Zimmerman, Molly E.; Yannakoulia, Mary; Kosmidis, Mary H.; Dardiotis, Efthimios; Hadjigeorgiou, Georgios; Sakka, Paraskevi; Stern, Yaakov; Scarmeas, Nikolaos; Mayeux, Richard (2019)
      Subjective cognitive decline may reflect a dementia prodrome or modifiable risk factor such as sleep disturbance. What is the association between sleep and subjective cognitive decline? Cross-sectional design, from two ...
    • Article  

      SPECT and PET imaging in Alzheimer's disease 

      Valotassiou, Varvara; Malamitsi, Julia; Papatriantafyllou, John; Dardiotis, Efthimios; Tsougos, Ioannis; Psimadas, Dimitrios; Alexiou, Sotiria; Hadjigeorgiou, George; Georgoulias, Panagiotis (2018)
      Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Beta-amyloid (Aβ) deposition and neurofibrillary tangles (NFTs) of abnormal hyperphosphorylated tau protein are ...
    • Article  

      TNFRSF13C/BAFFR P21R and H159Y polymorphisms in multiple sclerosis 

      Ntellas, Panagiotis; Dardiotis, Efthimios; Sevdali, Eirini; Siokas, Vasileios; Aloizou, Athina-Maria; Tsinti, Gerasimina; Germenis, Anastasios E.; Hadjigeorgiou, Georgios M.; Eibel, Hermann; Speletas, Matthaios (2020)
      Recent studies implicate B cells in multiple sclerosis (MS) pathogenesis, and consequently, several molecules participating in B cell survival and proliferation, including B-cell activating factor (BAFF), have recently ...