Browsing by Author "Dubyak, G."
Now showing items 1-1 of 1
-
Article
Resistance to etoposide in human leukemia HL-60 cells: Reduction in drug-induced DNA cleavage associated with hypophosphorylation of topoisomerase II phosphopeptides
Ganapathi, R.; Constantinou, Andreas I.; Kamath, N.; Dubyak, G.; Grabowski, D.; Krivacic, K. (1996)Tumor cell resistance to anthracyclines and epipodophyllotoxins can be due to reduced drug accumulation and/or alterations in the activity of topoisomerase II (TOPO II). HL-60 cells selected in 0.05 μg/ml doxorubicin (DOX) ...