Browsing by Author "Grimm, Jan"

Now showing items 1-3 of 3

    • Article  

      Acid specific dark quencher QC1 pHLIP for multi-spectral optoacoustic diagnoses of breast cancer 

      Roberts, Sheryl; Strome, Arianna; Choi, Crystal; Andreou, Chrysafis; Kossatz, Susanne; Brand, Christian; Williams, Travis; Bradbury, Michelle; Kircher, Moritz F.; Reshetnyak, Yana K.; Grimm, Jan; Lewis, Jason S.; Reiner, Thomas (2019)
      Breast cancer is the most common type of malignant growth in women. Early detection of breast cancer, as well as the identification of possible metastatic spread poses a significant challenge because of the structural and ...
    • Article  

      Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors 

      Kaittanis, Charalambos; Andreou, Chrysafis; Hieronymus, Haley; Mao, Ninghui; Foss, Catherine A.; Eiber, Matthias; Weirich, Gregor; Panchal, Palak; Gopalan, Anuradha; Zurita, Juan; Achilefu, Samuel; Chiosis, Gabriela; Ponomarev, Vladimir; Schwaiger, Markus; Carver, Brett S.; Pomper, Martin G.; Grimm, Jan (2018)
      Prostate-specific membrane antigen (PSMA) or folate hydrolase 1 (FOLH1) is highly expressed on prostate cancer. Its expression correlates inversely with survival and increases with tumor grade. However, the biological role ...
    • Article  

      Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer 

      Roberts, Sheryl; Andreou, Chrysafis; Choi, Crystal; Donabedian, Patrick; Jayaraman, Madhumitha; Pratt, Edwin C.; Tang, Jun; Pérez-Medina, Carlos; Cruz, M. Jason de la; Mulder, Willem J. M.; Grimm, Jan; Kircher, Moritz; Reiner, Thomas (2018)
      Optoacoustic imaging offers the promise of high spatial resolution and, at the same time, penetration depths well beyond the conventional optical imaging technologies, advantages that would be favorable for a variety of ...