Browsing by Author "Johnston,Patrick"

Now showing items 1-10 of 10

    • Article  

      Brain surface anatomy in adults with autism: The relationship between surface area, cortical thickness, and autistic symptoms 

      Ecker,C.; Ginestet, Cedric E.; Feng, Yue; Johnston,Patrick; Lombardo,Michael V.; Lai,Meng-Chuan; Suckling,John; Palaniyappan, Lena; Daly,Eileen M.; Murphy,Clodagh M.; Williams,Steven C. R.; Bullmore,Edward T.; Baron-Cohen,Simon; Brammer, Michael; Murphy,Declan G. M. (2013)
      Context: Neuroimaging studies of brain anatomy in autism spectrum disorder (ASD) have mostly been based on measures of cortical volume (CV). However, CV is a product of 2 distinct parameters, cortical thickness (CT) and ...
    • Article  

      Cognition in Males and Females with Autism: Similarities and Differences 

      Lai,Meng-Chuan; Lombardo,Michael V.; Ruigrok,Amber N. V.; Chakrabarti,B.; Wheelwright,Sally J.; Auyeung, Bonnie; Allison, Carrie; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Catani, Marco; Craig, Michael C.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Stewart, R.; Suckling,John; Williams,Steven C. R.; Baron-Cohen,Simon (2012)
      The male bias in autism spectrum conditions (ASC) has led to females with ASC being under-researched. This lack of attention to females could hide variability due to sex that may explain some of the heterogeneity within ...
    • Article  

      Frontal networks in adults with autism spectrum disorder 

      Catani, Marco; Dell’Acqua, Flavio; Budisavljevic, Sanja; Howells, Henrietta; Schotten, Thiebaut De; Froudist-Walsh, Sean; D'Anna, Lucio; Thompson, A.; Sandrone, Stefano; Bullmore,Edward T.; Suckling,John; Baron-Cohen,Simon; Lombardo,Michael V.; Wheelwright,Sally J.; Chakrabarti,B.; Lai,Meng-Chuan; Ruigrok,Amber N. V.; Leemans, Alexander; Ecker,C.; Craig, Michael C.; Murphy,Declan G. M.; Bailey, Anthony J.; Bolton, P. F.; Carrington, S.; Daly,Eileen M.; Deoni,Sean C. L.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Ruigrok,Amber N. V.; Sadek,Susan A.; Spain,D.; Stewart, R.; Williams,Steven C. R. (2016)
      It has been postulated that autism spectrum disorder is underpinned by an 'atypical connectivity' involving higher-order association brain regions. To test this hypothesis in a large cohort of adults with autism spectrum ...
    • Article  

      Individual differences in brain structure underpin empathizing-systemizing cognitive styles in male adults 

      Lai,Meng-Chuan; Lombardo,Michael V.; Chakrabarti,B.; Ecker,C.; Sadek,Susan A.; Wheelwright,Sally J.; Murphy,Declan G. M.; Suckling,John; Bullmore,Edward T.; Baron-Cohen,Simon; Bailey, Anthony J.; Bolton, P. F.; Carrington, S.; Daly,Eileen M.; Deoni,Sean C. L.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Pasco, Greg; Ruigrok,Amber N. V.; Spain,D.; Stewart, R.; Williams,Steven C. R. (2012)
      Individual differences in cognitive style can be characterized along two dimensions: 'systemizing' (S, the drive to analyze or build 'rule-based' systems) and 'empathizing' (E, the drive to identify another's mental state ...
    • Article  

      The neuropsychology of male adults with high-functioning autism or asperger syndrome 

      Wilson, C. E.; Happé,Francesca; Wheelwright,Sally J.; Ecker,C.; Lombardo,Michael V.; Johnston,Patrick; Daly,Eileen M.; Murphy,Clodagh M.; Spain,D.; Lai,Meng-Chuan; Chakrabarti,B.; Sauter, Disa A.; Baron-Cohen,Simon; Murphy,Declan G. M. (2014)
      Autism Spectrum Disorder (ASD) is diagnosed on the basis of behavioral symptoms, but cognitive abilities may also be useful in characterizing individuals with ASD. One hundred seventy-eight high-functioning male adults, ...
    • Article  

      Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? 

      Cadman, T.; Spain,D.; Johnston,Patrick; Russell, A.; Mataix-Cols, D.; Craig, Michael C.; Deeley, Q.; Robertson, D. M.; Murphy,Clodagh M.; Gillan, N.; Wilson, C. E.; Mendez, M.; Ecker,C.; Daly,Eileen M.; Findon, J.; Glaser, K.; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Chakrabarti,B.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Steward, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R.; Happé,Francesca; Murphy,Clodagh M. (2015)
      Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD ...
    • Article  

      On the brain structure heterogeneity of autism: Parsing out acquisition site effects with significance-weighted principal component analysis 

      Martinez-Murcia, Francisco; Lai,Meng-Chuan; Górriz, Juan Manuel; Ramirez, Javier; Young, Adam M. H.; Deoni,Sean C. L.; Ecker,C.; Lombardo,Michael V.; MRC AIMS Consortium; Baron-Cohen,Simon; Murphy,Declan G. M.; Bullmore,Edward T.; Suckling,John; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Catani, Marco; Chakrabarti,B.; Craig, Michael C.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lai,Meng-Chuan; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Ruigrok,Amber N. V.; Sadek,Susan A.; Spain,D.; Stewart, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R. (2017)
      Neuroimaging studies have reported structural and physiological differences that could help understand the causes and development of Autism Spectrum Disorder (ASD). Many of them rely on multisite designs, with the recruitment ...
    • Article  

      Relationship between surface-based brain morphometric measures and intelligence in autism spectrum disorders: Influence of history of language delay 

      Balardin, J. B.; Sato, J. R.; Vieira, G.; Feng, Yue; Daly,Eileen M.; Murphy,Clodagh M.; Bailey, Anthony J.; Carrington, S.; Jezzard, Peter; Stewart, R.; Baron-Cohen,Simon; Bullmore,Edward T.; Chakrabarti,B.; Henty, Julian; Lai,Meng-Chuan; Lombardo,Michael V.; Pasco, Greg; Ruigrok,Amber N. V.; Sadek,Susan A.; Suckling,John; Wheelwright,Sally J.; Bolton, P. F.; Catani, Marco; Craig, Michael C.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Spain,D.; Williams,Steven C. R.; Wilson, C. E.; Murphy,Clodagh M. (2015)
      Autism spectrum disorders (ASD) are a group of conditions that show abnormalities in the neuroanatomy of multiple brain regions. The variability in the development of intelligence and language among individuals on the ...
    • Article  

      White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder 

      Sundram, F.; Deeley, Q.; Sarkar, S.; Daly,Eileen M.; Latham, R.; Craig, Michael C.; Raczek, M.; Fahy, T.; Picchioni, M.; Barker, G. J.; Murphy,Declan G. M.; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Chakrabarti,B.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lai,Meng-Chuan; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Steward, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R. (2012)
      Antisocial personality disorder (ASPD) and psychopathy involve significant interpersonal and behavioural impairments. However, little is known about their underlying neurobiology and in particular, abnormalities in white ...
    • Article  

      White-matter relaxation time and myelin water fraction differences in young adults with autism 

      Deoni,Sean C. L.; Zinkstok, J. R.; Daly,Eileen M.; Ecker,C.; Williams,Steven C. R.; Murphy,Declan G. M.; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Chakrabarti,B.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Steward, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R. (2015)
      Background. Increasing evidence suggests that autism is associated with abnormal white-matter (WM) anatomy and impaired brain 'connectivity'. While myelin plays a critical role in synchronized brain communication, its ...