Browsing by Author "Jokinen, Jussi"
Now showing items 1-4 of 4
-
Article
Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents
Jokinen, Jussi; Boström, Adrian E.; Dadfar, Ali; Ciuculete, Diana M.; Chatzittofis, Andreas; Åsberg, Marie; Schiöth, Helgi B. (2018)The aim of this study, comprising 88 suicide attempters, was to identify hypothalamic-pituitary-adrenal (HPA) -axis coupled CpG-sites showing methylation shifts linked to severity of the suicide attempt. Candidate methylation ...
-
Article
High Plasma Oxytocin Levels in Men With Hypersexual Disorder
Jokinen, Jussi; Flanagan, John; Chatzittofis, Andreas; Öberg, Katarina; Arver, Stefan (2019)Background: Hypersexual disorder (HD) integrating pathophysiological aspects such as sexual desire deregulation, sexual addiction, impulsivity and compulsivity was suggested as a diagnosis for the ...
-
Article
Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes
Chatzittofis, Andreas; Boström, Adrian E.; Ciuculete, Diana-Maria; Flanagan, John N.; Krattinger, Regina; Bandstein, Marcus; Mwinyi, Jessica; Kullak-Ublick, Gerd A.; Öberg, Katarina Görts; Arver, Stefan; Schiöth, Helgi B.; Jokinen, Jussi (2020)Hypersexual disorder (HD) was proposed as a diagnosis in the DSM-5 and the classification ‘Compulsive Sexual Behavior Disorder’ is now presented as an impulse-control disorder in ICD-11. HD incorporates several pathophysiological ...
-
Article
Testosterone, LH levels and methylation status in hypersexual men
Chatzittofis, Andreas; Boström, Adrian; Öberg, Katarina; Flanagan, John; Schiöth, Helgi; Arver, Stefan; Jokinen, Jussi (2017)Background: Hypersexual disorder integrates aspects of sexual addiction, impulsivity and compulsivity and is related to HPA axis dysregulation. Gonadal influence and the function of HPG axis in hypersexual disorder is ...