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Browsing by Author "Kapsimali, Violetta"

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    • Article  

      Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism and circulating ACE levels are not associated with outcome in critically ill septic patients 

      Tsantes, Argirio E.; Tsangaris, I.; Kopterides, Petros; Nikolopoulos, Georgios K.; Kalamara, Eleni; Antonakos, Georgios; Kapsimali, Violetta; Gialeraki, Argiri; Dimopoulou, Ioanna; Orfanos, S.; Dima, Kleanthi; Travlou, Anthi S.; Armaganidis, Apostolos (2012)
      Background: In critically ill patients independent studies have shown contradictory findings regarding the prognostic significance of the D/D genotype of the I/D angiotensin converting enzyme (ACE) polymorphism. The study ...

    • Article  

      The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: A mendelian randomization meta-analysis 

      Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Tsangaris, I.; Tsiara, Chrissa G.; Kopterides, Petros; Vaiopoulos, A.; Kapsimali, Violetta; Bonovas, Stefanos; Tsantes, Argirio E. (2014)
      Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased in individuals carrying the 4G allele at position -675 of the PAI-1 gene. In turn, overexpression of PAI-1 has been found ...

    • Article  

      Association between the plasminogen activator inhibitor-1 4G/5G gene polymorphism and ischemic stroke; A meta-analysis. 

      Nikolopoulos, Georgios K.; Tsantes, Argirio E.; Bagos, Pantelis G.; Tsiara, Chrissa G.; Mantzios, Georgios P.; Kapsimali, Violetta; Pappa, Vassiliki; Travlou, Anthi S. (2006)

    • Article  

      Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Rapti, E.; Mantzios, Georgios P.; Kapsimali, Violetta; Travlou, Anthi S. (2007)
      The effect of the 675 insertion/deletion (4G/5G) polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene on the risk of venous thromboembolism (VTE) remains controversial. In this study, we performed a meta-analysis ...

    • Article  

      Comparison between Nageotte and flow cytometric counting of residual leucocytes in freshly prepared leucocyte-reduced red blood cell components 

      Nikolopoulos, Georgios K.; Kyriakou, Elias; Nearchakos, Nikolaos; Bonovas, Stefanos; Makri, Efstathia; Pantavou, Katerina; Kottaridi, Christine; Gialeraki, Argyri; Douramani, Panagiota; Taichert, Maria; Kapsimali, Violetta; Tsantes, Argirios E. (2018)
      Background Flow cytometry (FC) and Nageotte hemocytometry represent the most widely accepted methods for counting residual white blood cells (rWBCs) in leucocyte-reduced (LR) blood components. Our aim was to study the ...

    • Article  

      Direct evidence for normalization of platelet function resulting from platelet count reduction in essential thrombocythemia 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Tsirigotis, P.; Zoi, K.; Zomas, A.; Kapsimali, Violetta; Kopterides, Petros; Chondropoulos, Spyros; Dervenoulas, John; Mantzios, Georgios P. (2011)
      Essential thrombocythemia is characterized by persistent elevation and functional disturbances of platelets. Both the platelet function analyzer-100 (PFA-100) collagen-epinephrine (CEPI) cartridge and aggregometry with ...

    • Article  

      Effect of angiotensin converting enzyme gene I/D polymorphism and its expression on clinical outcome in acute respiratory distress syndrome 

      Tsantes, Argirio E.; Kopterides, Petros; Bonovas, Stefanos; Bagos, Pantelis G.; Antonakos, Georgios; Nikolopoulos, Georgios K.; Gialeraki, Argiri; Kapsimali, Violetta; Kyriakou, Elias; Kokoris, Styliani; Dima, Kleanthi; Armaganidis, Apostolos; Tsangaris, I. (2013)
      Background. The role of the D allele of the angiotensin-converting enzyme (ACE) gene I/D polymorphism in the clinical outcomes of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) remains ...

    • Article  

      The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis 

      Tsantes, Argirio E.; Tsangaris, I.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Kopterides, Petros; Antonakos, Georgios; Dimopoulou, Ioanna; Vrioni, G.; Kapsimali, Violetta; Dima, Kleanthi; Armaganidis, Apostolos; Travlou, Anthi S. (2010)
      Background. There is considerable evidence that elevated plasma homocysteine levels are associated with a prothrombotic milieu, whereas activation of the coagulation cascade is an important component of the pathogenesis ...

    • Article  

      Laboratory Assessment of the Anticoagulant Activity of Apixaban in Patients With Nonvalvular Atrial Fibrillation 

      Nikolopoulos, Georgios K.; Kyriakou, Elias; Katogiannis, Konstantinos; Ikonomidis, Ignatios; Giallouros, George; Rapti, Evdoxia; Taichert, Maria; Pantavou, Katerina; Gialeraki, Argiri; Kousathana, Foteini; Poulis, Aristarchos; Tsantes, Andreas G.; Bonovas, Stefanos; Kapsimali, Violetta; Tsivgoulis, Georgios; Tsantes, Argirios E. (2018)
      Our aim is to determine the most appropriate laboratory tests, besides anti-factor Xa (anti-FXa) chromogenic assays, to estimate the degree of anticoagulation with apixaban and compare it with that of rivaroxaban in ...

    • Article  

      Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of ischemic stroke: A meta-analysis 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Tsiara, Chrissa G.; Kapsimali, Violetta; Travlou, Anthi S.; Vaiopoulos, G. (2007)
      This study investigated the hypothesis that the insertion/deletion (4G/5G) polymorphism of the plasminogen activator inhibitor type-1 gene affects the risk for ischemic stroke, since results concerning this association ...

    • Article  

      Thromboelastometry for diagnosis of neonatal sepsis-associated coagulopathy: an observational study 

      Nikolopoulos, Georgios; Sokou, Rozeta; Giallouros, George; Konstantinidi, Aikaterini; Pantavou, Katerina; Bonovas, Stefanos; Lytras, Theodore; Kyriakou, Elias; Lambadaridis, Ioannis; Gounaris, Antonis; Douramani, Panagiota; Valsami, Serena; Kapsimali, Violetta; Iacovidou, Nicoletta; Tsantes, Argirios E. (2018)
      Our aim was to evaluate the potential role of standard extrinsically activated thromboelastometry (EXTEM) assay in the early detection of neonatal sepsis. We studied 91 hospitalized neonates categorized in two groups: group ...

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