Browsing by Author "Kircher, Moritz F."
Now showing items 1-5 of 5
-
Article
Acid specific dark quencher QC1 pHLIP for multi-spectral optoacoustic diagnoses of breast cancer
Roberts, Sheryl; Strome, Arianna; Choi, Crystal; Andreou, Chrysafis; Kossatz, Susanne; Brand, Christian; Williams, Travis; Bradbury, Michelle; Kircher, Moritz F.; Reshetnyak, Yana K.; Grimm, Jan; Lewis, Jason S.; Reiner, Thomas (2019)Breast cancer is the most common type of malignant growth in women. Early detection of breast cancer, as well as the identification of possible metastatic spread poses a significant challenge because of the structural and ...
-
Article
Distorted Phthalocyanines by Click Chemistry: Photoacoustic, Photothermal, and Surface-Enhanced Resonance Raman Studies
Rizvi, Waqar; Berisha, Naxhije; Farley, Christopher; Bhupathiraju, N. V. S. Dinesh K.; Andreou, Chrysafis; Khwaja, Emaad; Fuentes, German V.; Kircher, Moritz F.; Gao, Ruomei; Drain, Charles Michael (2019)Abstract Distortion of nominally planar phthalocyanine macrocycles affects the excited state dynamics in that most of the excited-state energy decays through internal conversion. A click-type annulation reaction on a ...
-
Article
DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy
Pal, Suchetan; Ray, Angana; Andreou, Chrysafis; Zhou, Yadong; Rakshit, Tatini; Wlodarczyk, Marek; Maeda, Masatomo; Toledo-Crow, Ricardo; Berisha, Naxhije; Yang, Jiang; Hsu, Hsiao-Ting; Oseledchyk, Anton; Mondal, Jagannath; Zou, Shengli; Kircher, Moritz F. (2019)Recently, surface-enhanced Raman scattering nanoprobes have shown tremendous potential in oncological imaging owing to the high sensitivity and specificity of their fingerprint-like spectra. As current Raman scanners rely ...
-
Article
Non-invasive In Vivo Imaging of Cancer Using Surface-Enhanced Spatially Offset Raman Spectroscopy (SESORS)
Nicolson, Fay; Andreiuk, Bohdan; Andreou, Chrysafis; Hsu, Hsiao-Ting; Rudder, Scott; Kircher, Moritz F. (2019)Rationale: The goal of imaging tumors at depth with high sensitivity and specificity represents a significant challenge in the field of biomedical optical imaging. 'Surface enhanced Raman scattering' (SERS) nanoparticles ...
-
Article
Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
Andreou, Chrysafis; Oseledchyk, Anton; Nicolson, Fay; Berisha, Naxhije; Pal, Suchetan; Kircher, Moritz F. (2019)Ovarian cancer represents the deadliest gynecologic malignancy. Most patients present at an advanced stage (FIGO stage III or IV), when local metastatic spread has already occurred. However, ovarian cancer has a unique ...