• Article  

      Dynamics of respiratory symptoms during infancy and associations with wheezing at school age 

      Usemann, Jakob; Xu, Binbin; Delgado-Eckert, Edgar; Korten, Insa; Anagnostopoulou, Pinelopi; Gorlanova, Olga; Kuehni, Claudia; Röösli, Martin; Latzin, Philipp; Frey, Urs (2018)
      Children with frequent respiratory symptoms in infancy have an increased risk for later wheezing, but the association with symptom dynamics is unknown. We developed an observer-independent method to characterise symptom ...
    • Article  

      Infant multiple breath washout using a new commercially available device: Ready to replace the previous setup? 

      Kentgens, Anne-Christianne; Guidi, Marisa; Korten, Insa; Kohler, Lena; Binggeli, Severin; Singer, Florian; Latzin, Philipp; Anagnostopoulou, Pinelopi (2018)
      INTRODUCTION: Multiple breath washout (MBW) is a sensitive test to measure lung volumes and ventilation inhomogeneity from infancy on. The commonly used setup for infant MBW, based on ultrasonic flowmeter, requires extensive ...
    • Article  

      Lower exhaled nitric oxide in infants with Cystic Fibrosis compared to healthy controls 

      Korten, Insa; Liechti, Margot; Singer, Florian; Hafen, Gaudenz; Rochat, Isabelle; Anagnostopoulou, Pinelopi; Müller-Suter, Dominik; Usemann, Jakob; Moeller, Alexander; Frey, Urs; Latzin, Philipp; Casaulta, Carmen; SCILD and BILD study group (2018)
      Exhaled nitric oxide (FENO) is a well-known, non-invasive airway biomarker. In patients with Cystic Fibrosis (CF) FENO is decreased. To understand if reduced FENO is primary related to Cystic Fibrosis Transmembrane Conductance ...
    • Article  

      Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth 

      Korten, Insa; Kieninger, Elisabeth; Yammine, Sophie; Cangiano, Giulia; Nyilas, Sylvia; Anagnostopoulou, Pinelopi; Singer, Florian; Kuehni, Claudia E.; Regamey, Nicolas; Frey, Urs; Casaulta, Carmen; Spycher, Ben D.; Latzin, Philipp; SCILD; BILD study group (2018)
      BACKGROUND: Lung impairment in cystic fibrosis (CF) starts in infancy. However, tools to monitor early lung disease are limited. Respiratory rate (RR) as a key vital sign is easy to assess during sleep and is elevated ...