Browsing by Author "Li, H."
Now showing items 1-5 of 5
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Benzene oligocarboxylic acids: Characterization by isocratic, linear gradient, and frontal anion-exchange chromatography
Li, H.; Lue, L.; Patrickios, Costas S. (1999)A series of nine benzene oligocarboxylic acids is characterized using anion-exchange chromalography to determine the steric mass-action affinity parameters: the characteristic charge, the equilibrium ion-exchange constant ...
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Article
The Ink4/Arf locus is a barrier for iPS cell reprogramming
Li, H.; Collado, M.; Villasante, A.; Strati, Katerina; Ortega, S.; Cãamero, M.; Blasco, M. A.; Serrano, M. (2009)The mechanisms involved in the reprogramming of differentiated cells into induced pluripotent stem (iPS) cells by the three transcription factors Oct4 (also known as Pou5f1), Klf4 and Sox2 remain poorly understood. The ...
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Article
Oligoacetic acid characterization by isocratic and linear salt gradient anion-exchange chromatography
Li, H.; Patrickios, Costas S. (2001)A homologous series of four oligomers of acetic acid (namely acetic acid, succinic acid, tricarballylic acid, and tetracarboxylic acid) is characterized using isocratic and linear salt gradient anion-exchange chromatography. ...
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Article
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
Marión, R. M.; Strati, Katerina; Li, H.; Murga, M.; Blanco, R.; Ortega, S.; Fernandez-Capetillo, O.; Serrano, M.; Blasco, M. A. (2009)The reprogramming of differentiated cells to pluripotent cells (induced pluripotent stem (iPS) cells) is known to be an inefficient process. We recently reported that cells with short telomeres cannot be reprogrammed to ...
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Article
Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells
Marion, R. M.; Strati, Katerina; Li, H.; Tejera, A.; Schoeftner, S.; Ortega, S.; Serrano, M.; Blasco, M. A. (2009)Telomere shortening is associated with organismal aging. iPS cells have been recently derived from old patients