Browsing by Author "Noel, J."

Now showing items 1-3 of 3

Article

A method for large-scale, high-yield isolation of canine pancreatic islets of Langerhans

Noel, J.; Rabinovitch, A.; Olson, L.; Kyriakides, George K.; Miller, Jody C.; Mintz, D. H. (1982)

A modified collagenase digestion method is described for the isolation of large numbers of islets from the canine pancreas ( 3500 islets/g). The islets isolated by this technique remained viable and released insulin in ...
Article

Responses of canine lymphocytes to allogeneic and autologous islets of Langerhans in mixed cell cultures

Miller, Jody C.; Rabinovitch, A.; Fuller, L.; Kyriakides, George K.; Severyn, W.; Noel, J.; Flaa, C.; Mintz, D. H. (1981)

Collagenase-isolated islets might possess specific antigens that might lead to unique alloimmune reactions following islet transplantation. In this report, we have examined lymphocyte immune recognition in vitro, i.e., the ...
Article

Responses of canine lymphocytes to allogeneic and autologous islets of Langerhans in mixed cell cultures

Rabinovitch, A.; Fuller, L.; Mintz, D. H.; Severyn, W.; Noel, J.; Flaa, C.; Kyriakides, George K.; Miller, Jody C. (1981)

Because successful allotransplantation of islets of Langerhans isolated by collagenase digestion has been difficult in many animal species, we asked whether isolated islet preparations might have tissue specific determinants ...