• Article  

      Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis 

      Kalli, Maria; Mpekris, Fotios; Wong, Chen K.; Panagi, Myrofora; Ozturk, Sait; Thiagalingam, Sam; Stylianopoulos, Triantafyllos; Papageorgis, Panagiotis (2019)
      Metastatic dissemination of cancer cells to distal organs is the major cause of death for patients suffering from the aggressive basal-like breast cancer (BLBC) subtype. Recently, we have shown that interleukin 13 receptor ...
    • Article  

      Constructing personalized longitudinal holo’omes of colon cancer-prone humans and their modeling in flies and mice 

      Panagi, Myrofora; Georgila, Konstantina; Eliopoulos, Aristides G.; Apidianakis, Yiorgos (2019)
      https://doi.org/10.18632/oncotarget.6463 Myrofora Panagi, Konstantina Georgila, Aristides G. Eliopoulos, Yiorgos Apidianakis
    • Article  

      Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment 

      Martin, John D.; Panagi, Myrofora; Wang, Chenyu; Khan, Thahomina T.; Martin, Margaret R.; Voutouri, Chrysovalantis; Toh, Kazuko; Papageorgis, Panagiotis; Mpekris, Fotios; Polydorou, Christiana; Ishii, Genichiro; Takahashi, Shinichiro; Gotohda, Naoto; Suzuki, Toshiyuki; Wilhelm, Matthew E.; Melo, Vinicio Alejandro; Quader, Sabina; Norimatsu, Jumpei; Lanning, Ryan M.; Kojima, Motohiro; Stuber, Matthew David; Stylianopoulos, Triantafyllos; Kataoka, Kazunori; Cabral, Horacio (2019)
      Dexamethasone is a glucocorticoid steroid with anti-inflammatory properties used to treat many diseases, including cancer, in which it helps manage various side effects of chemo-, radio-, and immunotherapies. Here, we ...
    • Article  

      Intertwined trade-offs coordinate Drosophila midgut mitosis vs. endoreplication and host defense vs. dysplasia 

      Tamamouna, Vasilia; Panagi, Myrofora; Theophanous, Andria; Demosthenous, Maria; Michail, Maria; Papadopoulou, Markella; Teloni, Savvas; Pitsouli, Chrysoula; Apidianakis, Yiorgos (2019)
      Inflammatory signaling supports host defense against infection, not only through immune cells, but also via regeneration of damaged tissue. Heightened regeneration, nevertheless, predisposes for all types of cancer and ...
    • Article  

      Unpredictable Effects of the Genetic Background of Transgenic Lines in Physiological Quantitative Traits 

      Evangelou, Amalia; Ignatiou, Anastasia; Antoniou, Chloi; Kalanidou, Sofia; Chatzimatthaiou, Sotiroula; Shianiou, Gavriella; Ellina, Soteroulla; Athanasiou, Rafaella; Panagi, Myrofora; Apidianakis, Yiorgos; Pitsouli, Chrysoula (2019)
      Physiology, fitness and disease phenotypes are complex traits exhibiting continuous variation in natural populations. To understand complex trait gene functions transgenic lines of undefined genetic background are often ...