• Article  

      Activity and toxicity of GI147211 in breast, colorectal and non-small-cell lung cancer patients: An EORTC-ECSG phase II clinical study 

      Gamucci, T.; Paridaens, R.; Heinrich, B.; Schellens, J. H. M.; Pavlidis, Nicholas; Verweij, J.; Sessa, Cristiana; Kaye, Stanley B.; Roelvink, M.; Wanders, J.; Hanauske, A. R. (2000)
      Background: GI147211 is a water-soluble synthetic analogue of camptothecin showing promising in vivo and in vitro antitumor activity and an acceptable toxicity profile. Patients and methods: Between April 1995 and November ...
    • Article  

      The current and future role of the medical oncologist in the professional care for cancer patients: A position paper by the European Society for Medical Oncology (ESMO) 

      Popescu, R. A.; Schäfer, R.; Califano, R.; Eckert, R.; Coleman, R.; Douillard, J.-Y.; Cervantes, A.; Casali, Paolo G.; Sessa, Cristiana; Cutsem, E. van; Vries, Elisabeth G. E. de; Pavlidis, Nicholas; Fumasoli, K.; Wörmann, B.; Samonigg, H.; Cascinu, S.; Hernández, J. J. C.; Howard, A. J.; Ciardiello, F.; Stahel, R. A.; Piccart, M. (2014)
      The number of cancer patients in Europe is rising and significant advances in basic and applied cancer research are making the provision of optimal care more challenging. The concept of cancer as a systemic, highly ...
    • Article  

      ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016 

      Dittrich, Christian; Kosty, Michael P.; Jezdic, Svetlana; Pyle, Doug; Berardi, Rossana; Bergh, Jonas; El-Saghir, Nagi; Lotz, Jean-Pierre; Österlund, Pia; Pavlidis, Nicholas; Purkalne, Gunta; Awada, Ahmad; Banerjee, Susana; Bhatia, Smita; Bogaerts, Jan; Buckner, Jan; Cardoso, Fatima; Casali, Paolo G.; Chu, Edward; Close, Julia Lee; Coiffier, Bertrand; Connolly, Roisin; Coupland, Sarah; Petris, Luigi De; Santis, Maria De; Vries, Elisabeth G. E. de; Dizon, Don S.; Duff, Jennifer; Duska, Linda R.; Eniu, Alexandru; Ernstoff, Marc; Felip, Enriqueta; Fey, Martin F.; Gilbert, Jill; Girard, Nicolas; Glaudemans, Andor W. J. M.; Gopalan, Priya K.; Grothey, Axel; Hahn, Stephen M.; Hanna, Diana; Herold, Christian; Herrstedt, Jørn; Homicsko, Krisztian; Jones, Dennie V.; Jost, Lorenz M.; Keilholz, Ulrich; Khan, Saad; Kiss, Alexander; Köhne, Claus-Henning; Kunstfeld, Rainer; Lenz, Heinz-Josef; Lichtman, Stuart; Licitra, Lisa; Lion, Thomas; Litière, Saskia; Liu, Lifang; Loehrer, Patrick J.; Markham, Merry Jennifer; Markman, Ben; Mayerhoefer, Marius; Meran, Johannes G.; Michielin, Olivier; Moser, Elizabeth Charlotte; Mountzios, Giannis; Moynihan, Timothy; Nielsen, Torsten; Ohe, Yuichiro; Öberg, Kjell; Palumbo, Antonio; Peccatori, Fedro A.; Pfeilstöcker, Michael; Raut, Chandrajit; Remick, Scot C.; Robson, Mark; Rutkowski, Piotr; Salgado, Roberto; Schapira, Lidia; Schernhammer, Eva; Schlumberger, Martin; Schmoll, Hans-Joachim; Schnipper, Lowell; Sessa, Cristiana; Shapiro, Charles L.; Steele, Julie; Sternberg, Cora N.; Stiefel, Friedrich; Strasser, Florian; Stupp, Roger; Sullivan, Richard; Tabernero, Josep; Travado, Luzia; Verheij, Marcel; Voest, Emile; Vokes, Everett; Roenn, Jamie Von; Weber, Jeffrey S.; Wildiers, Hans; Yarden, Yosef (2016)
      The European Society for Medical Oncology (ESMO) and the American Society of Clinical Oncology (ASCO) are publishing a new edition of the ESMO/ASCO Global Curriculum (GC) thanks to contribution of 64 ESMO-appointed and 32 ...
    • Article  

      The ESMO guideline strategy: An identity statement and reflections on improvement 

      Pentheroudakis, George; Cardoso, Fatima; Arnold, D.; Sessa, Cristiana; Peters, S.; Horwich, A.; Pavlidis, Nicholas; Stahel, R. A.; Cervantes, A. (2015)
      Guidelines should provide recommendations on the optimal management of a patient in specific clinical circumstances based on the scientific evidence. ESMO, as Europe's leading society in medical oncology produces a range ...
    • Article  

      Population pharmacokinetic and dynamic analysis of the topoisomerase I inhibitor lurtotecan in phase II studies 

      Schellens, J. H. M.; Heinrich, B.; Lehnert, M.; Gore, M. E.; Kaye, Stanley B.; Dombernowsky, P.; Paridaens, R.; Oosterom, A. T. Van; Verweij, J.; Loos, W. J.; Calvert, H.; Pavlidis, Nicholas; Cortes-Funes, H.; Wanders, J.; Roelvink, M.; Sessa, Cristiana; Selinger, K.; Wissel, P. S.; Gamucci, T.; Hanauske, A. R. (2002)
      Population pharmacokinetic-dynamic analysis was prospectively integrated in a broad phase II program of lurtotecan (GI147211), a novel camptothecin derived topoisomerase I inhibitor, to determine the population pharmacokinetic ...