Browsing by Author "Singer, Florian"

Now showing items 1-6 of 6

    • Article  

      Comparison of different analysis algorithms to calculate multiple-breath washout outcomes 

      Anagnostopoulou, Pinelopi; Kranz, Nadja; Wolfensberger, Jeremias; Guidi, Marisa; Nyilas, Sylvia; Koerner-Rettberg, Cordula; Yammine, Sophie; Singer, Florian; Latzin, Philipp (2018)
      Lung clearance index (LCI) is the main outcome of the multiple-breath washout (MBW) test. Current recommendations for LCI acquisition are based on low-grade evidence. The aim of this study was to challenge those recommendations ...
    • Article  

      Infant multiple breath washout using a new commercially available device: Ready to replace the previous setup? 

      Kentgens, Anne-Christianne; Guidi, Marisa; Korten, Insa; Kohler, Lena; Binggeli, Severin; Singer, Florian; Latzin, Philipp; Anagnostopoulou, Pinelopi (2018)
      INTRODUCTION: Multiple breath washout (MBW) is a sensitive test to measure lung volumes and ventilation inhomogeneity from infancy on. The commonly used setup for infant MBW, based on ultrasonic flowmeter, requires extensive ...
    • Article  

      An innovative lung model for multiple breath washout testing in health and disease 

      Anagnostopoulou, Pinelopi; Vomsattel, Sarah; Kentgens, Anne-Christiane; Guidi, Marisa; Binggeli, Severin; Kohler, Lena; Singer, Florian; Latzin, Philipp; Obrist, Dominik (2019)
      Background Multiple breath washout (MBW) is a lung function test that identifies the degree of ventilation inhomogeneity (VI) in the lungs. In vitro validation of MBW devices is recommended. So far, plastic lung models for ...
    • Article  

      Lower exhaled nitric oxide in infants with Cystic Fibrosis compared to healthy controls 

      Korten, Insa; Liechti, Margot; Singer, Florian; Hafen, Gaudenz; Rochat, Isabelle; Anagnostopoulou, Pinelopi; Müller-Suter, Dominik; Usemann, Jakob; Moeller, Alexander; Frey, Urs; Latzin, Philipp; Casaulta, Carmen; SCILD and BILD study group (2018)
      Exhaled nitric oxide (FENO) is a well-known, non-invasive airway biomarker. In patients with Cystic Fibrosis (CF) FENO is decreased. To understand if reduced FENO is primary related to Cystic Fibrosis Transmembrane Conductance ...
    • Article  

      Normative data for multiple breath washout outcomes in school-aged Caucasian children 

      Anagnostopoulou, Pinelopi; Latzin, Philipp; Jensen, Renee; Stahl, Mirjam; Harper, Alana; Yammine, Sophie; Usemann, Jakob; Foong, Rachel E.; Spycher, Ben; Hall, Graham L.; Singer, Florian; Stanojevic, Sanja; Mall, Marcus; Ratjen, Felix; Ramsey, Kathryn A. (2019)
      Background The nitrogen multiple breath washout (N2MBW) technique is increasingly used to assess the degree of ventilation inhomogeneity in school-aged children with lung disease. However, reference values for healthy ...
    • Article  

      Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth 

      Korten, Insa; Kieninger, Elisabeth; Yammine, Sophie; Cangiano, Giulia; Nyilas, Sylvia; Anagnostopoulou, Pinelopi; Singer, Florian; Kuehni, Claudia E.; Regamey, Nicolas; Frey, Urs; Casaulta, Carmen; Spycher, Ben D.; Latzin, Philipp; SCILD; BILD study group (2018)
      BACKGROUND: Lung impairment in cystic fibrosis (CF) starts in infancy. However, tools to monitor early lung disease are limited. Respiratory rate (RR) as a key vital sign is easy to assess during sleep and is elevated ...