Browsing by Author "Stavrou, Emmanouil"
Now showing items 1-3 of 3
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Article
Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae
Kyriakou, DImitris; Stavrou, Emmanouil; Demosthenous, Panayiota; Angelidou, Georgia; San Luis, B. -J; Boone, Charles M.; Promponas, Vasilis J.; Kirmizis, Antonis (2016)Background: Transcriptome studies have revealed that many eukaryotic genomes are pervasively transcribed producing numerous long non-coding RNAs (lncRNAs). However, only a few lncRNAs have been ascribed a cellular role ...
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Article
Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity
Molina-Serrano, D.; Schiza, V.; Demosthenous, Christis; Stavrou, Emmanouil; Oppelt, J.; Kyriakou, DImitris; Liu, W.; Zisser, G.; Bergler, H.; Dang, W.; Kirmizis, Antonis (2016)Changes in histone modifications are an attractive model through which environmental signals, such as diet, could be integrated in the cell for regulating its lifespan. However, evidence linking dietary interventions with ...
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Article
Single-Cell Tracing Dissects Regulation of Maintenance and Inheritance of Transcriptional Reinduction Memory
Bheda, Poonam; Aguilar-Gómez, Diana; Becker, Nils B.; Becker, Johannes; Stavrou, Emmanouil; Kukhtevich, Igor; Höfer, Thomas; Maerkl, Sebastian; Charvin, Gilles; Marr, Carsten; Kirmizis, Antonis; Schneider, Robert (2020)Transcriptional memory of gene expression enables adaptation to repeated stimuli across many organisms. However, the regulation and heritability of transcriptional memory in single cells and through divisions remains poorly ...