Browsing by Author "Vraka, Panayiota S."
Now showing items 1-3 of 3
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Article
Induction of caspase-independent programmed cell death by vitamin E natural homologs and synthetic derivatives.
Constantinou, Constantina; Hyatt, John Anthony; Vraka, Panayiota S.; Papas, Andreas M.; Papas, Konstantinos A.; Neophytou, Christiana M.; Hadjivassiliou, V.; Constantinou, Andreas I. (2009)Current observations in the literature suggest that vitamin E may be a suitable candidate for cancer chemotherapy. To investigate this further, we examined the ability of the vitamin E natural homologs [alpha-, beta-, ...
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Article
Induction of DNA damage and caspase-independent programmed cell death by vitamin e
Constantinou, Constantina; Neophytou, Christiana M.; Vraka, Panayiota S.; Hyatt, John Anthony; Papas, Konstantinos A.; Constantinou, Andreas I. (2012)Vitamin E comprises 8 functionally unique isoforms and may be a suitable candidate for the adjuvant treatment of prostate cancer. In this study, we examined the ability of 2 vitamin E isoforms [α-tocotrienol (γ-TT) and ...
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Article
Synthesis and study of the cancer cell growth inhibitory properties of α-, γ-tocopheryl and γ-tocotrienyl 2-phenylselenyl succinates
Vraka, Panayiota S.; Drouza, Chryssoula; Rikkou, Maria P.; Odysseos, Andreani D.; Keramidas, Anastasios D. (2006)Vitamin E succinate selenium-conjugated molecules were synthesized and their apoptogenic properties were evaluated. 4-Methyl-2-phenylselenyl succinate (4) was prepared by the reaction of sodium benzeneselenolate with ...