• Article  

      Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs 

      Bousquet, Jean; Schunemann, H. J.; Samolinski, B.; Demoly, Pascal; Baena-Cagnani, C. E.; Bachert, C.; Bonini, S.; Boulet, L. P.; Bousquet, Jean; Brozek, J. L.; Canonica, G. W.; Casale, T. B.; Cruz, A. A.; Fokkens, W. J.; Fonseca, J. A.; Wick, R. G. van; Grouse, L.; Haahtela, T.; Khaltaev, N.; Kuna, P.; Lockey, R. F.; Carlsen, K. C. Lodrup; Mullol, J.; Naclerio, R. N.; O'Hehir, R. E.; Ohta, K.; Palkonen, S.; Papadopoulos, N. G.; Passalacqua, G.; Pawankar, R.; Price, D.; Ryan, D.; Simons, F. E. R.; Togias, A.; Williams, D. M.; Yorgancioglu, A.; Yusuf, O. M.; Aberer, W.; Adachi, M.; Agache, I.; Aït-Khaled, N.; Akdis, C. A.; Andrianarisoa, A.; Annesi-Maesano, I.; Ansotegui, I. J.; Baiardini, I.; Bateman, E. D.; Bedbrook, Anna; Beghé, B.; Beji, M.; Bel, E. H.; Kheder, A. Ben; Bennoor, K. S.; Bergmann, K. C.; Berrissoul, F.; Bieber, T.; Bindslev-Jensen, C.; Blaiss, M. S.; Boner, A. L.; Bouchard, J.; Braido, F.; Brightling, C. E.; Bush, A.; Caballero-Fonseca, F.; Calderon, M. A.; Calvo, M. A.; Camargos, P. A. M.; Caraballo, L. R.; Carlsen, K. H.; Carr, W.; A.M, Cepeda Sarabia; Cesario, A.; Chavannes, Niels H.; Chen, Y. Z.; Chiriac, A. M.; Pérez, T. Chivato; Chkhartishvili, E.; Ciprandi, G.; Costa, David J.; Cox, L.; Custovic, Adnan; Dahl, R.; Darsow, U.; Blay, F. De; Deleanu, D.; Denburg, J. A.; Devillier, P.; Didi, T.; Dokic, D.; Dolen, W. K.; Douagui, H. B.; Dubakiene, R.; Durham, S. R.; Dykewicz, M. S.; El-Gamal, Y.; El-Meziane, A.; Emuzyte, R.; Fiocchi, A.; Fletcher, M.; Fukuda, T.; Gamkrelidze, A.; Gereda, J. E.; Diaz, S. González; Gotua, M.; Guzmán, M. A.; Hellings, P. W.; Hellquist-Dahl, B.; Horak, F.; Hourihane, J. O. B.; Howarth, P. H.; Humbert, M.; Ivancevich, J. C.; Jackson, Rod T.; Just, J.; Kalayci, O.; Kaliner, M. A.; Kalyoncu, A. F.; Keil, T.; Keith, P. K.; Khayat, G.; Kim, Y. Y.; N'Goran, B. Koffi; Koppelman, G. H.; Kowalski, M. L.; Kull, I.; Kvedariene, V.; Larenas-Linnemann, D.; Le, Tuyen D.; Lemière, C.; Li, J.; Lieberman, P.; Lipworth, B. J.; Mahboub, B.; Makela, M. J.; Martin, F.; Marshall, G. D.; Martinez, F. D.; Masjedi, M. R.; Maurer, M.; Mavale-Manuel, S.; Mazon, A.; Melén, E.; Meltzer, E. O.; Mendez, N. H.; Merk, H.; Mihaltan, F.; Mohammad, Y.; Almeida, M. Morais; Muraro, A.; Nafti, S.; Namazova-Baranova, L.; Nekam, K.; Neou, A.; Niggemann, B.; Nizankowska-Mogilnicka, E.; Nyembue, T. D.; Okamoto, Y.; Okubo, K.; Orru, M. P.; Ouedraogo, S.; Ozdemir, C.; Panzner, P.; Pali-Schöll, I.; Park, H. S.; Pigearias, B.; Pohl, W.; Popov, T. A.; Postma, D. S.; Potter, P.; Rabe, K. F.; Ratomaharo, J.; Reitamo, S.; Ring, J.; Roberts, R.; Rogala, B.; Romano, A.; Rodriguez, M. Roman; Rosado-Pinto, J.; Rosenwasser, L.; Rottem, M.; Sanchez-Borges, M.; Scadding, G. K.; Schmid-Grendelmeier, P.; Sheikh, A.; Sisul, J. C.; Sole, D.; Sooronbaev, T.; Spicak, V.; Spranger, O.; Stein, R. T.; Stoloff, S. W.; Sunyer, Jordi; Szczeklik, A.; Todo-Bom, A.; Toskala, E.; Tremblay, Y.; Valenta, R.; Valero, A. L.; Valeyre, D.; Valiulis, A.; Valovirta, E.; Cauwenberge, P. Van; Vandenplas, O.; Weel, C. Van; Vichyanond, P.; Viegi, Giovanni; Wang, D. Y.; Wickman, M.; Wöhrl, S.; Wright, J.; Yawn, B. P.; Yiallouros, Panayiotis K.; Zar, H. J.; Zernotti, M. E.; Zhong, N.; Zidarn, M.; Zuberbier, T.; Ang, C. S.; Baigenzhin, A. K.; Boakye, D. A.; Briggs, A. H.; Burney, P. G.; Busse, W. W.; Chuchalin, Alexander G.; Haddad, H.; Johnston, S. L.; Kogevinas, M.; Levy, L. M.; Mohammadi, A.; Oddie, S.; Rezagui, D.; Terreehorst, I.; Warner, J. O. (2012)
      Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a ...
    • Article  

      Association of serum vitamin D with asthma and atopy in childhood: Review of epidemiological observational studies 

      Kolokotroni, Ourania; Middleton, Nicos; Kouta, Christiana; Raftopoulos, V.; Yiallouros, Panayiotis K. (2015)
      During the last decades, vitamin D deficiency has re-emerged worldwide affecting not only population’s bone health, but also several other conditions including asthma and allergies. Increasing number of published epidemiological ...
    • Article  

      Association of vitamin D receptor gene polymorphisms and vitamin D levels with asthma and atopy in Cypriot adolescents: a case-control study 

      Papadopoulou, A.; Kouis, Panayiotis; Middleton, Nicos; Kolokotroni, Ourania; Karpathios, Themistocles; Nicolaidou, P.; Yiallouros, Panayiotis K. (2015)
      Background: Polymorphisms in the vitamin D receptor (VDR) gene have been studied in immune-related disorders either as independent contributors or in combination with vitamin D concentration. Vitamin D and VDR have been ...
    • Article  

      Asthma and atopy in children born by caesarean section: effect modification by family history of allergies - a population based cross-sectional study 

      Kolokotroni, Ourania; Middleton, Nicos; Gavatha, Marina; Lamnisos, Demetris; Priftis, K. N.; Yiallouros, Panayiotis K. (2012)
      Background: Studies on the association of birth by caesarean section (C/S) and allergies have produced conflicting findings. Furthermore, evidence on whether this association may differ in those at risk of atopy is limited. ...
    • Article  

      Asthma: The role of low high-density-lipoprotein cholesterol in childhood and adolescence 

      Yiallouros, Panayiotis K.; Savva, Savvas C.; Kolokotroni, Ourania; Dima, Kleanthi; Zerva, A.; Kouis, Panayiotis; Bousquet, Jean; Middleton, Nicos (2014)
      Background: Several studies have examined the relationship of asthma with serum dyslipidemia and reported positive, negative or no association. Most studies were limited by their cross-sectional design and the wide age ...
    • Article  

      The effect of inhaled budesonide on adrenal and growth suppression in asthmatic children 

      Priftis, K. N.; Papadimitriou, A.; Gatsopoulou, E.; Yiallouros, Panayiotis K.; Fretzayas, Andrew; Nicolaidou, P. (2006)
      The present authors evaluated adrenal reserve in asthmatic children on long-term inhaled corticosteroids and whether possible adrenal suppression could be predicted by growth retardation. Low-dose synacthen test (0.5 μg·1.73 ...
    • Article  

      Impact of early diagnosis and control of chronic respiratory diseases on active and healthy ageing: A debate at the European Union Parliament 

      Bousquet, Jean; Tanasescu, C. C.; Camuzat, Thierry; Anto, Josep M.; Blasi, F.; Neou, A.; Palkonen, S.; Papadopoulos, N. G.; Antunes, J. Pinto; Samolinski, B.; Yiallouros, Panayiotis K.; Zuberbier, T. (2013)
    • Article  

      Impact of psychiatric illness upon asthma patients’ health care utilization and illness control. Are all psychiatric comorbidities created equal? 

      Pilipenko, Nataliya; Karekla, Maria; Georgiou, A.; Feldman, Jonathan (2016)
      The impact of psychiatric illnesses upon asthma patients' functioning is not well understood. This study examined the impact of psychiatric comorbidity upon illness management in asthma patients using empirically-derived ...
    • Article  

      Leukotriene antagonists: As firstline asthmatic therapy: A review 

      Wozniak, Greta; Kotrotsiou, E.; Roupa, Z. (2005)
      Asthma is a chronic inflammatory disorder characterized by airflow obstruction. The development of leukotriene receptor antagonists and synthesis inhibitors in briefly described; and acute exercise, allergen, and aspirin ...
    • Article  

      Low serum high-density lipoprotein cholesterol in childhood is associated with adolescent asthma 

      Yiallouros, Panayiotis K.; Savva, Savvas C.; Kolokotroni, Ourania; Behbod, B.; Zenios, Michalis; Economou, Mary; Chadjigeorgiou, C.; Kourides, Y. A.; Tornaritis, M. J.; Lamnisos, Demetris; Middleton, Nicos; Milton, Donald K. (2012)
      Background: Whilst emerging evidence from animal and cell experiments has shown high-density lipoprotein cholesterol to have anti-inflammatory effects consistent with a protective role in asthma, human studies investigating ...
    • Article  

      MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): The new generation guideline implementation 

      Bousquet, Jean; Schunemann, H. J.; Fonseca, J. A.; Samolinski, B.; Bachert, C.; Canonica, G. W.; Casale, T. B.; Cruz, A. A.; Demoly, Pascal; Hellings, P. W.; Valiulis, A.; Wickman, M.; Zuberbier, T.; Bosnic-Anticevitch, S.; Bedbrook, Anna; Bergmann, K. C.; Caimmi, D. P.; Dahl, R.; Fokkens, W. J.; Grisle, I.; Carlsen, K. C. Lodrup; Mullol, J.; Muraro, A.; Palkonen, S.; Papadopoulos, N.; Passalacqua, G.; Ryan, D.; Valovirta, E.; Yorgancioglu, A.; Aberer, W.; Agache, I.; Adachi, M.; Akdis, C. A.; Akdis, M.; Annesi-Maesano, I.; Ansotegui, I. J.; Anto, Josep M.; Arnavielhe, S.; Arshad, S. H.; Baiardini, I.; Baigenzhin, A. K.; Barbara, Cristina; Bateman, E. D.; Beghé, B.; Bel, E. H.; Kheder, A. Ben; Bennoor, K. S.; Benson, M.; Bewick, M.; Bieber, T.; Bindslev-Jensen, C.; Bjermer, L.; Blain, Hubert; Boner, A. L.; Boulet, L. P.; Bonini, M.; Bonini, S.; Bosse, I.; Bourret, Rodolphe; Bousquet, Jean; Braido, F.; Briggs, A. H.; Brightling, C. E.; Brozek, J. L.; Buhl, R.; Burney, P. G.; Bush, A.; Caballero-Fonseca, F.; Calderon, M. A.; Camargos, P. A. M.; Camuzat, Thierry; Carlsen, K. H.; Carr, W.; A.M, Cepeda Sarabia; Chavannes, Niels H.; Chatzi, L.; Chen, Y. Z.; Chiron, R.; Chkhartishvili, E.; Chuchalin, Alexander G.; Ciprandi, G.; Cirule, I.; Correia-Da-Sousa, J.; Cox, L.; Crooks, George; Costa, David J.; Custovic, Adnan; Dahlen, S. E.; Darsow, U.; Carlo, G. De; Blay, F. De; Dedeu, Antoni; Deleanu, D.; Denburg, J. A.; Devillier, P.; Didier, A.; Dinh-Xuan, A. T.; Dokic, D.; Douagui, H. B.; Dray, G.; Dubakiene, R.; Durham, S. R.; Dykewicz, M. S.; El-Gamal, Y.; Emuzyte, R.; Fink-Wagner, A.; Fletcher, M.; Fiocchi, A.; Forastiere, F.; Gamkrelidze, A.; Gemicioǧlu, B.; Gereda, J. E.; Diaz, S. González; Gotua, M.; Grouse, L.; Guzmán, M. A.; Haahtela, T.; Hellquist-Dahl, B.; Heinrich, J.; Horak, F.; Hourihane, J. O. B.; Howarth, P. H.; Humbert, M.; Hyland, M. E.; Ivancevich, J. C.; Jares, E. J.; Johnston, S. L.; Joos, G.; Jonquet, Olivier; Jung, K. S.; Just, J.; Kaidashev, I. P.; Kalayci, O.; Kalyoncu, A. F.; Keil, T.; Keith, P. K.; Khaltaev, N.; Klimek, L.; N'Goran, B. Koffi; Kolek, V.; Koppelman, G. H.; Kowalski, M. L.; Kull, I.; Kuna, P.; Kvedariene, V.; Lambrecht, B.; Lau, S.; Larenas-Linnemann, D.; Laune, D.; Le, Tuyen D.; Lieberman, P.; Lipworth, B. J.; Li, J.; Louis, R.; Magard, Y.; Magnan, A.; Mahboub, B.; Majer, I.; Makela, M. J.; Manning, P. J.; Keenoy, E. De Manuel; Marshall, G. D.; Masjedi, M. R.; Maurer, M.; Mavale-Manuel, S.; Melén, E.; Gomes, Elisabete Melo; Meltzer, E. O.; Merk, H.; Miculinic, N.; Mihaltan, F.; Milenkovic, B.; Mohammad, Y.; Molimard, M.; Momas, I.; Montilla-Santana, A.; Almeida, M. Morais; Mosges, R.; Namazova-Baranova, L.; Naclerio, R. N.; Neou, A.; Neffen, H.; Nekam, K.; Niggemann, B.; Nyembue, T. D.; O'Hehir, R. E.; Ohta, K.; Okamoto, Y.; Okubo, K.; Ouedraogo, S.; Paggiaro, P. L.; Pali-Schöll, I.; Palmer, S.; Panzner, P.; Papi, A.; Park, H. S.; Pavord, I.; Pawankar, R.; Pfaar, O.; Picard, R.; Pigearias, B.; Pin, I.; Plavec, D.; Pohl, W.; Popov, T. A.; Portejoie, F.; Postma, D. S.; Potter, P.; Price, D.; Rabe, K. F.; Raciborski, F.; Radier-Pontal, F.; Repka-Ramirez, S.; Robalo-Cordeiro, C.; Rolland, C.; Rosado-Pinto, J.; Reitamo, S.; Rodenas, F.; Rodriguez, M. Roman; Romano, A.; Rosario, N. A.; Rosenwasser, L.; Rottem, M.; Sanchez-Borges, M.; Scadding, G. K.; Serrano, E.; Schmid-Grendelmeier, P.; Sheikh, A.; Simons, F. E. R.; Sisul, J. C.; Skrindo, I.; Smit, H. A.; Sole, D.; Sooronbaev, T.; Spranger, O.; Stelmach, R.; Strandberg, T.; Sunyer, Jordi; Thijs, C.; Todo-Bom, A.; Triggiani, M.; Valenta, R.; Valero, A. L.; Hage, M. van; Vandenplas, O.; Vezzani, G.; Vichyanond, P.; Viegi, Giovanni; Wagenmann, M.; Walker, S.; Wang, D. Y.; Wahn, U.; Williams, D. M.; Wright, J.; Yawn, B. P.; Yiallouros, Panayiotis K.; Yusuf, O. M.; Zar, H. J.; Zernotti, M. E.; Zhang, L.; Zhong, N.; Zidarn, M.; Mercier, Jacques (2015)
      Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for ...
    • Article  

      Prevalence of asthma and allergies in children from the Greek-Cypriot and Turkish-Cypriot communities in Cyprus: A bi-communal cross-sectional study 

      Lamnisos, Demetris; Moustaki, Maria; Kolokotroni, Ourania; Koksoy, H.; Faiz, Muharrem; Arifoglu, Kenan; Milton, Donald K.; Middleton, Nicos; Yiallouros, Panayiotis K. (2013)
      Background: The Greek-Cypriot (G/C) and Turkish-Cypriot (T/C) communities have lived apart since 1974, with the former presumably adopting a more westernized way of life. We estimated the prevalence of asthma and allergies ...
    • Article  

      Prevalence of asthma and respiratory symptoms in 15-17 year-old Greek-Cypriots by proximity of their community of residence to power plants: Cyprus 2006-07 

      Middleton, Nicos; Kolokotroni, Ourania; Lamnisos, Demetris; Koutrakis, Petros; Yiallouros, Panayiotis K. (2014)
      Objectives: Numerous studies have reported adverse effects of traffic pollution on respiratory health. Exposure to power plants emissions has not been as comprehensively studied. The prevalence of asthma and respiratory ...
    • Article  

      Shared genetic variants between serum levels of high-density lipoprotein cholesterol and wheezing in a cohort of children from Cyprus 

      Yiallouros, Panayiotis K.; Kouis, Panayiotis; Kolokotroni, Ourania; Youhanna, S.; Savva, Savvas C.; Dima, Kleanthi; Zerva, A.; Platt, D.; Middleton, Nicos; Zalloua, P. (2016)
      Background: In a cohort of children in Cyprus, we recently reported low levels of high density lipoprotein cholesterol (HDL-C) to be associated with asthma. We examined whether genetic polymorphisms that were previously ...
    • Article  

      Vitamin D levels and status amongst asthmatic and non-asthmatic adolescents in Cyprus: A comparative cross-sectional study 

      Kolokotroni, Ourania; Papadopoulou, A.; Middleton, Nicos; Kouta, Christiana; Raftopoulos, V.; Nicolaidou, P.; Yiallouros, Panayiotis K. (2015)
      Background: Emerging evidence suggests that vitamin D might be implicated in asthma pathophysiology. This study aims to compare Vitamin D mean serum levels and status between asthmatic and non-asthmatic adolescents and ...