Browsing by Subject "Autism"
Now showing items 1-20 of 20
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Alexithymia in children with and without autism spectrum disorders
(2016)Alexithymia refers to pronounced difficulty in identifying and describing one's own emotions and is associated with an externally oriented focus of thinking. Alexithymia is known to be much more common in adults with autism ...
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Atypical neural self-representation in autism
(2010)The 'self' is a complex multidimensional construct deeply embedded and in many ways defined by our relations with the social world. Individuals with autism are impaired in both self-referential and other-referential social ...
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Biological sex affects the neurobiology of autism
(2013)In autism, heterogeneity is the rule rather than the exception. One obvious source of heterogeneity is biological sex. Since autism was first recognized, males with autism have disproportionately skewed research. Females ...
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Brain and behavioral correlates of action semantic deficits in autism
(2013)Action-perception circuits containing neurons in the motor system have been proposed as the building blocks of higher cognition; accordingly, motor dysfunction should entail cognitive deficits. Autism spectrum conditions ...
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Decreased centrality of cortical volume covariance networks in autism spectrum disorders
(2015)Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by atypical structural and functional brain connectivity. Complex network analysis has been mainly used to describe altered ...
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The EU-AIMS Longitudinal European Autism Project (LEAP): Clinical characterisation
(2017)Background: The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). The current paper describes ...
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Hierarchical cortical transcriptome disorganization in autism
(2017)Background: Autism spectrum disorders (ASD) are etiologically heterogeneous and complex. Functional genomics work has begun to identify a diverse array of dysregulated transcriptomic programs (e.g., synaptic, immune, cell ...
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Imaging sex/gender and autism in the brain: Etiological implications
(2017)The male preponderance in autism prevalence has brought together the disparate topics of sex/gender and autism research. Two directions of neuroimaging studies on the relationships between sex/gender and autism may inform ...
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Impaired Communication Between the Motor and Somatosensory Homunculus Is Associated With Poor Manual Dexterity in Autism Spectrum Disorder
(2017)Background Fine motor skill impairments are common in autism spectrum disorder (ASD), significantly affecting quality of life. Sensory inputs reaching the primary motor cortex (M1) from the somatosensory cortex (S1) are ...
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Lost for emotion words: What motor and limbic brain activity reveals about autism and semantic theory
(2015)Autism spectrum conditions (ASC) are characterised by deficits in understanding and expressing emotions and are frequently accompanied by alexithymia, a difficulty in understanding and expressing emotion words. Words are ...
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Moral dilemmas film task: A study of spontaneous narratives by individuals with autism spectrum conditions
(2009)People with autism spectrum conditions (ASC) have difficulties with mentalizing, empathy, and narrative comprehension. A new test of social and narrative cognition, the Moral Dilemmas Film Task, was developed to probe ...
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Neuroanatomy of individual differences in language in adult males with autism
(2015)One potential source of heterogeneity within autism spectrum conditions (ASC) is language development and ability. In 80 high-functioning male adults with ASC, we tested if variations in developmental and current structural ...
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Relationship between surface-based brain morphometric measures and intelligence in autism spectrum disorders: Influence of history of language delay
(2015)Autism spectrum disorders (ASD) are a group of conditions that show abnormalities in the neuroanatomy of multiple brain regions. The variability in the development of intelligence and language among individuals on the ...
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The role of the self in mindblindness in autism
(2011)Since its inception the 'mindblindness' theory of autism has greatly furthered our understanding of the core social-communication impairments in autism spectrum conditions (ASC). However, one of the more subtle issues ...
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Self-referential and social cognition in a case of autism and agenesis of the corpus callosum
(2012)Background: While models of autism spectrum conditions (ASC) are emerging at the genetic level of analysis, clear models at higher levels of analysis, such as neuroanatomy, are lacking. Here we examine agenesis of the ...
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Sex/Gender Differences and Autism: Setting the Scene for Future Research
(2015)Objective The relationship between sex/gender differences and autism has attracted a variety of research ranging from clinical and neurobiological to etiological, stimulated by the male bias in autism prevalence. Findings ...
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A shift to randomness of brain oscillations in people with autism
(2010)Background Resting-state functional magnetic resonance imaging (fMRI) enables investigation of the intrinsic functional organization of the brain. Fractal parameters such as the Hurst exponent, H, describe the complexity ...
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Specialization of right temporo-parietal junction for mentalizing and its relation to social impairments in autism
(2011)Over the last 25 years, "mindblindness" (deficits in representing mental states) has been one of the primary explanations behind the hallmark social-communication difficulties in autism spectrum conditions (ASC). However, ...
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A typically rightward cerebral asymmetry in male adults with autism stratifies individuals with and without language delay
(2016)In humans, both language and fine motor skills are associated with left-hemisphere specialization, whereas visuospatial skills are associated with right-hemisphere specialization. Individuals with autism spectrum conditions ...
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White-matter relaxation time and myelin water fraction differences in young adults with autism
(2015)Background. Increasing evidence suggests that autism is associated with abnormal white-matter (WM) anatomy and impaired brain 'connectivity'. While myelin plays a critical role in synchronized brain communication, its ...