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Browsing by Subject "Biological markers"

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    • Article  

      The beginning of personalized medicine in sepsis: Small steps to a bright future 

      Christaki, Eirini; Giamarellos-Bourboulis, Evangelos J. (2014)
      There is a growing recognition that there is a need for a more personalized approach towards sepsis care. In most clinical trials investigating novel therapeutic interventions against sepsis, patients have been considered ...

    • Article  

      Impact of HIV type 1 DNA levels on spontaneous disease progression: A meta-analysis 

      Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Goujard, Cecile; Katzenstein, Terese L.; Minga, Albert K.; Rouzioux, C.; Hatzakis, A. (2012)
      Several studies have reported the prognostic strength of HIV-1 DNA with variable results however. The aims of the current study were to estimate more accurately the ability of HIV-1 DNA to predict progression of HIV-1 ...

    • Article  

      Low expression of p27 protein combined with altered p53 and Rb/p16 expression status is associated with increased expression of cyclin A and cyclin B1 in diffuse large B-cell lymphomas 

      Bai, M. C.; Vlachonikolis, J.; Agnantis, Niki J.; Tsanou, E.; Dimou, S.; Nikolaides, C.; Stefanaki, S. V.; Pavlidis, Nicholas; Kanavaros, P. (2001)
      The expression of the cyclin-dependent kinase inhibitor (CDKI) p27 protein was investigated in relation to (1) the expression of the cell cycle regulators p53, Rb and p16 and (2) the proliferation profile as determined by ...

    • Article  

      Molecular markers and biological targeted therapies in metastatic colorectal cancer: expert opinion and recommendations derived from the 11th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2009. 

      Cutsem, E. Van; Dicato, M.; Arber, N.; Berlin, J.; Cervantes, A.; Ciardiello, F.; Gramont, A. De; Diaz-Rubio, E.; Ducreux, M.; Geva, R.; Glimelius, B.; Glynne-Jones, R.; Grothey, Axel; Gruenberger, T.; Haller, D.; Haustermans, K.; Labianca, R.; Lenz, H. J.; Minsky, B.; Nordlinger, B.; Ohtsu, A.; Pavlidis, Nicholas; Rougier, P.; Schmiegel, W.; Velde, C. Van de; Schmoll, H. J.; Sobrero, A.; Tabernero, Josep (2010)
      The article summarizes the expert discussion and recommendations on the use of molecular markers and of biological targeted therapies in metastatic colorectal cancer (mCRC), as well as a proposed treatment decision strategy ...

    • Conference Object  

      Prenatal diagnosis of aneuploidy using artificial neural networks in relation to health economics 

      Neocleous, Andreas C.; Neocleous, Costas K.; Petkov, N.; Nicolaides, Kypros H.; Schizas, Christos N. (Springer Verlag, 2016)
      The early detection of fetal chromosomal abnormalities such as aneuploidies, has been an important subject in medicine over the last thirty years. A pregnant woman is advised by the doctor to perform an amniocentesis test, ...

    • Article  

      Trabectedin-related rhabdomyolysis: An uncommon but fatal toxicity 

      Stoyianni, A.; Kapodistrias, N.; Kampletsas, E. O.; Pentheroudakis, George; Pavlidis, Nicholas (2011)
      Rhabdomyolysis is defined as the dissolution of striped muscle characterized by the leakage of intracellular muscle components into the circulation, which can ultimately lead to renal failure with a possible fatal outcome. ...

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